Dalton (Analyze & Optimize) Profile picture
Sep 13, 2025 9 tweets 5 min read Read on X
HIGH CORTISOL: Here are 5 ways to lower it (backed by research):

#1 GABA

GABA completely stops cortisol.

25-50 mg orally halts it in response to physiological stress, improving:

⊙ Fatigue
⊙ Concentration
⊙ Physical discomfort

(🧵1/9) Image
GABA can suppress cortisol by its action in the brain.

The hypothalamus produces CRH ➞ pituitary to produce ACTH ➞ adrenals to produce cortisol.

GABA input to the hypothalamus calms these neurons, preventing CRH release and cortisol production.

(2/9) Image
Image
#2 Grounding

6 weeks of grounding completely normalized the cortisol pattern throughout the day.

& improved sleep.

The difference is dramatic in my experience (+ with clients).

(3/9) Image
With contact to the earth, the brain puts out less CRF,

a protein that starts the cascade that produces cortisol - making us stressed, jittery, restless and anxious.

Probably a big reason why we see grounding be so beneficial.

(4/9) Image
#3 Sugar

Experiments show that animals without adrenal glands produce less CRH (or CRF, same thing) when they consume sugar.

The more sugar they consume, the less CRF they produce.

Eating sugar can acutely lower cortisol (vs aspartame).

(5/9) Image
Image
Several neurons in the hypothalamus are considered to be glucose sensitive.

When blood sugar drops, they produce CRH to raise blood sugar.

But just eating sugar can quickly satisfy these neurons and stop the CRH production.

(6/9) Image
#4 DHEA

DHEA nearly cuts cortisol in half.

DHEA directly inhibits the production of cortisol in the adrenals and opposes all of the functions of cortisol:

☆ Relaxes mood
☆ Reduces belly fat
☆ Preserves brain function
☆ Puts on muscle
☆ Improves skin quality
☆ Improves immunity
☆ Reduces disease risk
☆ Improves mitochondrial function

25 mg per day here - we prefer to start at much lower amounts (<5 mg).

(7/9)Image
DHEA in a few ways to lower cortisol.

1. Suppresses cortisol-mediated gene expression
2. Inhibits 11βHSD1
3. Lowers the ratio of cortisol receptors (GRα to GRβ) - which suppresses cortisol receptor activation.

(8/9) Image
#5 Vitamin D

Vitamin D lowers cortisol by 40%.

Just 2,000 IU / day here, a few minutes outside during peak sun hours.

It also lowered blood pressure substantially (by 9/7 mmHg).

Likely by:

◈ Inhibiting 11BHSD1
◈ Lowering inflammation
◈ Controlling calcium balance in the brain
(9/9)Image

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dalton (Analyze & Optimize)

Dalton (Analyze & Optimize) Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @Outdoctrination

Feb 5
Vinegar drastically reduces blood sugar and insulin levels, according to multiple clinical trials.

(🧵1/7)Image
This first paper is a review article from 2017.

They looked at studies giving people vinegar alongside meals and monitored their blood sugar and insulin responses.

Having high levels of these post meal is highly indicative of insulin resistance and is a risk for heart disease.

Apologies, I do not have the official PDF so I'm working with the raw file here.Image
Here were the included studies.

Most are looking at roughly one tablespoon of vinegar alongside a meal with carbs. Image
Image
Image
Read 10 tweets
Feb 5
Why you SHOULDN'T be hysterical about vitamin C causing kidney stones, and what to do to prevent them (🧵1/10):Image
The idea that vitamin C supplementation can cause kidney stones is not completely baseless, but it does lack context.

Ascorbic acid, or vitamin C, can get metabolized in our cells to create oxalate.

Oxalate is what binds to calcium to form kidney stones in most people.

Seems pretty straightforward, BUT...Image
Ascorbic acid mainly gets converted to oxalate under conditions of high oxidative stress.

That is when ascorbic acid (AA) turns into dehydroascorbate (DHA).

But we have glutathione to help regenerate ascorbic acid from dehydroascorbate.

This depends on your entire antioxidant network.Image
Read 12 tweets
Feb 4
FLUORIDE: The toxin in your water that destroys thyroid function.

Here's how, and what to do about it.

(🧵1/14)Image
Image
In 2024 a massive review of studies was done on the effects of fluoride exposure and markers of thyroid health.

The higher the fluoride concentration in:

◈ Drinking water
◈ Urine
◈ Serum

the higher the TSH level was - a marker of primary hypothyroidism.

TSH rises when the thyroid gland does not respond to stimulation.Image
More importantly, this study showed a marked decrease in thyroid hormones from higher water fluoride concentrations.

The active T3 thyroid hormone and the precursor thyroid hormone T4 both drop off with higher water fluoride concentrations. Image
Read 16 tweets
Feb 3
A recent study showed that vitamin K2 was protective against every single metric of dental health measured.

(🧵1/8)Image
This paper came out in 2023 in Healthcare.

They aim was simple - look at vitamin K2 levels in relation to dental health.

They did this by looking at carboxylated osteocalcin levels - which reflects whole body K2 status. Image
Specifically they were looking at a condition called periodontitis.

This is essentially dental inflammation, especially in the gums but also impacting the teeth themselves.

These are the stages, with gingivitis being early and stage 5 being very severe. Image
Read 11 tweets
Feb 1
An astounding study shows that 1/2 a teaspoon of baking soda lowered inflammation within hours.

(🧵1/9)Image
Study was published in 2018 in The Journal of Immunology.

Some experiment were done in rodents including baking soda in the water.

Some groups had their vagus nerves cut.

Other animals had a surgery to disturb the spleen.

Both surgeries were done to see if these tissues mediated the effect of baking soda.

Then, the human studies were done comparing drinking 2g of baking soda dissolved in water vs 2g of salt.

(2/9)Image
Animals consuming baking soda in the water showed decreased inflammation in several areas.

In both the kidneys and in the spleen, they had decreased inflammatory M1 macrophages, one of the primary immune cells.

Baking soda increased M2 macrophages, signifying that the macrophages turned into a more anti-inflammatory phenotype.

They also had:

↑IL-10 in the kidney (anti-inflammatory cytokine)
↑FOXP3 cells in blood + kidney (Treg cells, anti-inflammatory immune cells)
↓CD4 T Cells (inflammatory)
↓CD44 T cells (inflammatory)
↓TNFα macrophages (primary inflammatory mediator)

(3/9)Image
Read 10 tweets
Jan 31
MOLD: A silent cause behind your health issues.

Fortunately, there are several tools we can use to directly bind and eliminate their toxins.

Here's 5 of the most useful (🧵1/7):

(IMPORTANT: READ UNTIL END)Image
#1 Humic acids

These are materials formed from organic matter decomposition, and it's found in shilajit.

This study showed that including them in the diet could both bind and prevent the liver cancer from a common food mycotoxin, aflotoxin B1.

Typically dosing starts at 100 mg.Image
#2 Bentonite

This is a clay substance that is highly efficient at binding to mycotoxins.

This paper showed ~50% reductions in key mycotoxins along with reduced organ damage.

Doses are higher, 500+ mg. Image
Image
Read 9 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(