🧵 Key Terms in Rheumatology — Simplified & Explained ⬇️
Rheumatology is full of terms like synovitis, enthesitis, tenosynovitis, dactylitis.
Let’s break them down in a clear way
1️⃣ Synovitis
= Inflammation of the synovial lining of a joint.
Signs: swelling, warmth, tenderness, ↓ ROM.
Seen in: RA, lupus arthritis, JIA.
Think: “the joint lining is angry.”
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2️⃣ Enthesitis
= Inflammation at the enthesis (where tendons/ligaments insert into bone).
Common in: Spondyloarthritis (PsA, AS, IBD-arthritis).
Typical sites: Achilles tendon, plantar fascia, costochondral junctions.
Pain is deep, localized, worse with stress.
3️⃣ Tenosynovitis
= Inflammation of the tendon sheath.
Classic example: de Quervain’s at wrist.
Also in RA, lupus, spondyloarthritis, infections (TB).
Feels like “painful sausage around the tendon.”
4️⃣ Dactylitis
= “Sausage digit” → uniform swelling of entire finger/toe.
Due to synovitis + tenosynovitis + enthesitis together.
Seen in: Psoriatic arthritis, reactive arthritis, sarcoidosis, sickle cell disease.
5️⃣ Bursitis
= Inflammation of a bursa (fluid-filled sac cushioning bone/tendon/joint).
Examples:
•Olecranon bursitis (“student’s elbow”)
•Prepatellar bursitis (“housemaid’s knee”)
Can be inflammatory (RA, gout) or infectious.
9️⃣ Raynaud’s Phenomenon
= Reversible color changes of fingers/toes on cold exposure or stress:
White → Blue → Red
Primary (benign) or Secondary (SSc, MCTD, lupus).
🔟 Takeaway
These terms aren’t just jargon.
They describe specific clinical patterns that point directly to diagnosis.
Mastering them = thinking like a rheumatologist 🔎
Share to spread knowledge.
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🧵 Thread: Approach to Low Back Ache: 1/ Low back ache (LBA) is one of the most common reasons patients visit a doctor.
But not every back pain is the same.
A structured approach helps us identify who needs urgent care, who needs simple reassurance, and who needs long-term management.
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2/ 🔑 First step: Duration
•Acute: <6 weeks
•Subacute: 6–12 weeks
•Chronic: >12 weeks
This simple classification guides the urgency and depth of evaluation.
3/ ⚠️ Red flags — NEVER miss these in back pain!
•Age <20 or >50 with new-onset pain
•Trauma
•History of cancer
•Unexplained weight loss
•Fever or immunosuppression
•Night pain / pain at rest
•Neurologic deficits (weakness, bladder/bowel involvement)
•Saddle anesthesia
Looking at a peripheral smear is like reading the story of a patient’s blood.
Here’s how to approach it 👇
@IhabFathiSulima @DrAkhilX #MedTwitter #Hematology
1. Normal Smear
•Central pallor ~1/3 of RBC diameter
•Round, biconcave cells
👉 Baseline before spotting abnormalities
2. Microcytosis
•Small RBCs with ↑ central pallor
Causes:
•Iron deficiency anemia
•Thalassemia
•Anemia of chronic disease (common in RA, SLE, SpA)
🧵 Hypercalcemia – A Clinical Approach plus Rheumatological causes:
1/ Hypercalcemia isn’t just “high calcium.”
It can cause kidney stones, bone pain, abdominal symptoms, psychiatric changes – and even cardiac arrest.
Here’s a structured approach 👇
@IhabFathiSulima @DrAkhilX #MedTwitter
2/ 🔎 Step 1 – Confirm
•Correct serum Ca for albumin OR check ionized Ca.
•Rule out lab error.
•Always assess severity & symptoms.
Mild: 10.5–12
Moderate: 12–14
Severe: >14 or symptomatic
🧵 Hypokalemia – A Clinical Thread plus Rheumatological causes: 1/ Hypokalemia = serum K+ < 3.5 mmol/L.
It may look “just a number” on labs, but in reality → can cause paralysis, arrhythmias, and death if missed.
Here’s the clinical approach 👇
@IhabFathiSulima @DrAkhilX #MedTwitter #RheumTwitter #Nephrology
Tweet 1:
Lupus Nephritis (LN) is one of the most serious complications of SLE—responsible for major morbidity & mortality.
Here’s an updated 2025 thread on LN 🧵
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Tweet 2:
⚠️ Clinical clues
•Proteinuria (often nephrotic range)
•Hematuria (microscopic or gross)
•Hypertension
•Reduced renal function
•Sometimes asymptomatic → only labs reveal disease