The Overlooked Causes of Parkinson’s Disease—and Prevention Strategies That Work
Avoiding pesticides and staying active can go a long way toward protecting your brain.
But one study found that a simple daily habit could reduce your risk by up to 80%.
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Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s disease.
In the United States alone, about 1.1 million people are currently living with this condition—a number expected to keep rising.
This progressive neurological disorder occurs when dopamine-producing neurons in the brain begin to degenerate, leading to movement- and emotion-related symptoms. It affects each person differently.
Though there isn’t a cure, certain lifestyle changes and natural approaches can help relieve symptoms effectively.
What Are the Symptoms and Early Signs of Parkinson’s Disease?
Parkinson’s disease symptoms usually begin gradually and may be subtle at first. Symptoms often start on one side of the body and typically remain more severe on that side, even as they progress.
Common symptoms may include:
• Tremor: The most common movement-related symptom is tremor—particularly the classic “pill-rolling” motion between thumb and forefinger—that usually starts in one hand during rest.
• Slowed movement: Moving more slowly and with greater difficulty. People may shuffle with shorter steps or have trouble rising from a chair.
• Rigid muscles: Experiencing muscle stiffness anywhere in the body, which can limit motion and often cause pain.
• Impaired posture and balance: Developing a stooped posture and experiencing balance problems or frequent falls.
• Loss of automatic movements: Showing fewer involuntary actions, such as blinking, smiling, or swinging the arms while walking.
Beyond movement changes, other early signs emerge gradually:
• Speech and swallowing changes: Speaking in a softer, more rapid, slurred, or monotone voice. Swallowing may become difficult, often starting with coughing during meals.
• Writing changes: Writing in smaller, more cramped handwriting that becomes increasingly difficult to produce.
• Reduced sense of smell: Losing or diminishing the ability to smell—an often-overlooked symptom may appear long before diagnosis and affect quality of life.
• Cognitive impairment: Having trouble focusing, carrying on conversations, or processing information quickly.
• Sleep problems: Experiencing insomnia or rapid eye movement sleep behavior disorder, which causes people to act out their dreams due to the absence of normal muscle paralysis during dreaming.
Parkinson’s disease has five stages:
• Stage 1: Mild Symptoms
Experiencing subtle symptoms that typically affect only one side of the body. Daily activities remain unaffected, though slight changes in posture, facial expression, or walking may be noticeable.
• Stage 2: Moderate Symptoms
Noticing symptoms appear on both sides of the body. Daily activities remain manageable but take more time due to increased muscle stiffness and slowed movement. Postural changes continue, but balance is not yet affected.
• Stage 3: Middle Stage
Developing balance impairments that increase the risk of falls. Movements slow down further, and basic tasks like dressing or eating become more challenging but are still possible without full assistance.
• Stage 4: Severe Symptoms
Losing the ability to live independently. People may be able to stand without help but typically require a walker or other assistance to walk. Daily tasks require significant help.
• Stage 5: Most Advanced Stage
Reaching the most debilitating stage. People are often bedridden or require a wheelchair. Severe stiffness, frequent falls, and cognitive decline—such as dementia and hallucinations—are common. Full-time care is necessary.
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What Causes Parkinson’s Disease?
Parkinson’s disease is a brain disorder that gradually worsens over time.
It occurs when brain cells—especially those that produce dopamine, a chemical that helps regulate movement—are lost or damaged.
When more than half of these dopamine-producing cells are gone, movement problems such as tremors, stiffness, slowness, and issues with balance and coordination begin to appear.
In Parkinson’s disease, the brain undergoes many changes.
The changes involves the presence of abnormal protein clumps called Lewy bodies. These clumps consist largely of alpha-synuclein, a protein that, in Parkinson’s, builds up in a way the brain cannot clear.
This buildup is a key focus of ongoing research, as it appears to drive disease progression. Some patients also have altered mitochondria, leading to brain cell damage.
For the vast majority of cases, the exact cause of Parkinson’s remains unknown. However, research points to a multifaceted interplay between genetic and environmental factors.
Chemical exposures represent a major environmental risk factor.
Long-term exposure to pesticides and herbicides significantly increases the risk—particularly for people working in agriculture or living in farming communities.
Veterans exposed to Agent Orange during the Vietnam War show notably higher rates of Parkinson’s disease. Industrial toxins, including certain workplace chemicals and heavy metals, may also contribute.
Some studies even suggest that contaminated well water in specific regions could raise the risk.
Risk factors for Parkinson’s disease:
• Age: The strongest known risk factor. Parkinson’s disease becomes more common with age, typically appearing in people in their 60s. However, about 5 percent to 10 percent of cases are diagnosed before age 50.
• Sex: Being male increases the risk. Parkinson’s disease is about 50 percent more common in men.
• Family history: Having a parent or sibling with Parkinson’s roughly doubles a person’s risk of developing the disease.
• Head injuries: A history of traumatic brain injury or repeated head trauma may increase the risk of Parkinson’s.
How Is Parkinson’s Disease Diagnosed?
Parkinson’s disease cannot be diagnosed with a single specific test. Instead, a neurologist evaluates the person’s medical history and symptoms and performs a neurological and physical examination to make a clinical diagnosis.
Diagnostic criteria, according to most clinical guidelines, include slowness of movement (bradykinesia) along with a resting tremor and/or rigidity.
Tests Commonly Used in Diagnosis
Diagnostic imaging tools can support—but not confirm—a Parkinson’s diagnosis. These may include:
• Single-photon emission computed tomography scan (SPECT): A nuclear imaging test that creates 3D images of organs and tissues using a radioactive tracer. Used to assess internal brain structures but is not specific to Parkinson’s.
• Dopamine transporter scan: A specialized type of SPECT imaging that visualizes the brain’s dopamine system.
• Magnetic resonance imaging scan (MRI): Produces detailed images of brain structure. Typically used to rule out other conditions rather than diagnose Parkinson’s directly.
• Transcranial sonography scan: An ultrasound technique used to help distinguish idiopathic Parkinson’s–the most common form, with no known cause—from other movement disorders.
• Positron emission tomography scan: Assesses brain function and activity, especially in areas related to movement.
Emerging Diagnostic Tools
New approaches are being developed to improve early and accurate diagnosis of Parkinson’s disease:
• Earwax analysis: An artificial intelligence-powered method that examines scent compounds in earwax and has demonstrated up to 94 percent accuracy in detecting the condition.
• Polymerase chain reaction-based blood test: A test that analyzes genetic material to identify early signs of Parkinson’s more quickly and noninvasively.
• Artificial-intelligence enhanced “magnetic pen”: A machine learning-driven device that detects subtle writing-related motor deficits, offering another noninvasive diagnostic option.
What Are the Treatments for Parkinson’s Disease?
While there’s no cure for Parkinson’s, a comprehensive treatment approach can significantly improve quality of life and slow the progression of symptoms.
1. Medication
Many medications for Parkinson’s disease either increase dopamine levels in the brain or mimic its effects.
• Carbidopa-levodopa: The most effective treatment for Parkinson’s symptoms. Levodopa is converted into dopamine in the brain, while carbidopa prevents levodopa from being converted too early outside the brain—ensuring more dopamine reaches its target. An inhaled version provides quick relief for managing intermittent “off” periods.
• Carbidopa-levodopa infusion: A gel form of the medication delivered directly to the small intestine through a feeding tube. This continuous delivery offers steady symptom control throughout the day and is used in advanced Parkinson’s disease.
• Vyalev (foscarbidopa and foslevodopa): Approved by the U.S. Food and Drug Administration in October 2024, Vyalev is the first 24-hour continuous subcutaneous levodopa infusion. It delivers steady dopamine levels to help reduce motor fluctuations.
• Dopamine agonists: These drugs act like dopamine in the brain and help improve movement symptoms. Other medications in this category include MAO-B inhibitors, COMT inhibitors, and A2A antagonists, which either keep dopamine from breaking down too quickly or help it work more effectively.
• Pimavanserin: A medication used specifically to treat hallucinations and delusions associated with Parkinson’s disease. It works on serotonin receptors and does not interfere with dopamine levels.
2. Deep Brain Stimulation (DBS)
DBS is typically recommended for people with advanced Parkinson’s disease who experience unpredictable responses to levodopa. The procedure involves implanting electrodes in the brain to help reduce tremors, stabilize medication effects, decrease involuntary movements, relieve muscle rigidity, and improve overall motor function.
3. MRI-Guided Focused Ultrasound (MRgFUS)
MRgFUS is a minimally invasive procedure used to manage tremors in some people with Parkinson’s disease.
4. Physical Therapy
Physical therapy plays a crucial role in managing motor and functional challenges associated with Parkinson’s disease. Physical therapists use targeted strategies to help reduce stiffness, tremors, balance issues, and walking difficulties.
5. Supplements
Some research suggests that adding specific supplements may help ease symptoms when added to a balanced diet:
• Coenzyme Q10: Supports cellular energy production and may slow early disease progression.
• Vitamins C and E: Known for antioxidant properties; high doses may reduce Parkinson’s risk.
• Cytidinediphosphocholine: A naturally occurring compound that may help increase dopamine levels and reduce reliance on levodopa.
• Nicotinamide adenine dinucleotide: A compound that serves as an active form of vitamin B3. It may help boost dopamine production, though study results have been mixed.
6. Traditional Chinese Medicine (TCM)
TCM views illness as the result of internal imbalances. Parkinson’s disease has historically been treated within this framework using therapies such as acupuncture.
Some people with Parkinson’s symptoms may find acupuncture helpful, especially as a complement to conventional treatment.
What Are the Lifestyle Approaches for Parkinson’s Disease?
Lifestyle changes are often recommended to help manage symptoms related to movement and communication—and may even enhance the effectiveness of treatment.
1. Mediterranean and Antioxidant-Rich Diet
Research consistently shows that the Mediterranean diet may delay Parkinson’s onset and slow disease progression. This eating pattern emphasizes olive oil as the primary fat source and includes fatty fish, fruits, vegetables, and whole grains. Regularly eating fatty fish rich in omega-3s provides brain-protective nutrients.
A meta-analysis published in February found that the Mediterranean diet may also reduce the risk of Parkinson’s disease by lowering inflammation, supporting healthy gut bacteria, and improving mitochondrial function.
Eating antioxidant-rich foods—such as berries, leafy greens, and colorful vegetables—may help combat oxidative stress, which contributes to the breakdown of dopamine-producing brain cells. Getting enough fiber can help manage constipation, a common issue in Parkinson’s.
Timing protein intake away from levodopa doses may improve medication absorption, while staying hydrated supports overall health and enhances the effectiveness of treatment.
2. Dopamine-Driven Exercise
Exercise plays a vital role in managing symptoms. It enhances mobility, balance, flexibility, and strength.
Physical activity increases dopamine levels in the brain. It is also believed to lower oxidative stress, inflammation, and the buildup of toxic alpha-synuclein clumps in the brain—which contribute to nerve cell death in Parkinson’s disease.
A 2024 study found that six months of intense exercise boosted dopamine in people with early Parkinson’s.
A 2021 meta-analysis found that bicycling significantly improved motor function—especially gait—as well as balance, walking speed, and overall quality of life. While cognitive benefits were less pronounced, cycling programs consistently produced positive physical outcomes.
Overall, bicycling appears to be a safe and effective intervention for improving movement and well-being in people with Parkinson’s disease.
Daily exercise—including activities like swimming and brisk walking—helps maintain muscle strength, flexibility, and mental well-being. Both moderate activities such as water aerobics and vigorous ones like jogging or hiking are beneficial.
3. Dance and Music
Dance classes designed for people with Parkinson’s help improve motor control and boost mood through music and social interaction.
A 2022 study found that while music initially improved participants’ gait, their walking improved even without music after class—suggesting they may have internalized the rhythm through dance.
Synchronized drumming activates the caudate nucleus—a brain region affected in Parkinson’s disease—and has been shown to improve mood, attention, and social connection.
In one study, people with Parkinson’s who participated in twice-weekly West African drum circle sessions for six weeks reported a significant improvement in quality of life.
The findings suggest that drumming may be a valuable complement to traditional therapies like physical therapy.
4. Massage
Massage therapy may improve circulation and reduce muscle spasms. Craniosacral therapy—a specialized massage technique that targets the brain and spinal column—may help lessen tremors and improve overall function.
5. Mind-Body Practices
Practices such as tai chi, yoga, and qigong can enhance balance, flexibility, and range of motion for people with Parkinson’s disease, while promoting better mood and sleep.
How Does Mindset Affect Parkinson’s Disease?
People living with Parkinson’s disease often face physical, emotional, and mental challenges that affect daily life.
A 2022 survey of more than 1,400 people with Parkinson’s found that 75 percent said maintaining a positive attitude significantly improved their quality of life. In addition, 70 percent reported needing some form of support, with emotional support identified as the most important.
Many respondents noted that humor and laughter were helpful—51 percent used them as coping tools, while nearly half drew strength from faith or spirituality.
Staying engaged in meaningful activities—such as volunteering, crafting, reading, journaling, meditating, shopping, painting, and spending time with loved ones—also played a key role in helping them stay positive and emotionally resilient.
How Can I Prevent Parkinson’s Disease?
There is no known way to prevent Parkinson’s disease, but certain lifestyle choices may help lower your risk.
• Diet: Eating enough protein can help prevent weight loss and muscle wasting while supporting healing and disease resistance. Maintaining a balanced diet is also important.
• Caffeine: Caffeine has neuroprotective effects and may reduce brain inflammation and oxidative stress—both linked to dopamine nerve loss. Multiple studies have associated caffeine consumption with a reduced risk of Parkinson’s. One study found that drinking at least 28 ounces of coffee daily in midlife lowered the risk of developing Parkinson’s disease by five times at age 65 compared to those who did not drink coffee.
• Gait training: Practicing gait exercises can improve balance, reduce the risk of falls, and correct abnormal walking patterns associated with Parkinson’s.
• Avoiding harmful chemicals: Reducing exposure to pesticides, herbicides, and industrial toxins may help lower the risk of Parkinson’s disease.
What Are the Complications of Parkinson’s Disease?
Parkinson’s disease can lead to various complications, many of which worsen as the condition progresses.
• Difficulty thinking: Many people with Parkinson’s develop impairment, dementia, or other thinking challenges, typically in the later stages. These complications may be managed with medications and behavioral interventions.
• Sleep problems: Difficulty falling asleep, frequent night awakenings, early waking, daytime sleepiness, and sleep apnea are common. Sleep apnea affects about 40 percent of people with Parkinson’s.
• Eating problems: Late-stage Parkinson’s can impair the muscles used for chewing, increasing the risk of choking. As the disease progresses, swallowing difficulties may lead to poor nutrition and saliva buildup, which can cause drooling.
• Bladder issues: About 30 percent to 60 percent of people with Parkinson’s experience urinary problems, such as difficulty urinating or loss of bladder control.
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Turns out, doctors knew something they weren’t supposed to say out loud.
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Ivermectin and hydroxychloroquine prescriptions “soared far above” levels before the COVID-19 pandemic, according to a new study.
Researchers from the University of California - Los Angeles (UCLA) and other institutions said that nearly 3 million ivermectin and hydroxychloroquine prescriptions were issued during the pandemic, totaling some $272 million, according to a news release issued on Feb. 20.
The dispensing of ivermectin “from US pharmacies was nearly 1,000 percent higher than prepandemic rates,” the study said.
Usage of the two drugs was three times higher in people aged 65 and older, compared with people aged 18 to 64, according to the study published in the Health Affairs journal.
Patients aged 65 and older represented 25 percent of adults in the study but constituted more than 59 percent of COVID-19-linked ivermectin usage and 68 percent of COVID-19-related hydroxychloroquine use, it found.
Hydroxychloroquine prescriptions and usage peaked in March 2020, when the pandemic started in the United States, to 133 percent of pre-pandemic rates, the UCLA news release said.
Meanwhile, ivermectin use increased dramatically throughout 2020 and 2021, the researchers noted. By August 2021, prescriptions for the drug had shot to more than 10 times higher than before the pandemic.
The clash no one saw coming: two blockbuster drugs working against each other.
Statins lower cholesterol—but new research shows they also slash GLP-1, the same hormone Ozempic is designed to restore.
It’s a metabolic paradox with life-changing consequences for millions.
And here’s the kicker: the damage might be reversible with a dirt-cheap supplement… yet no one is talking about it.
Why? The answer may have little to do with science—and everything to do with money.
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For decades, statins have been prescribed to tens of millions of Americans to lower cholesterol and ward off heart disease. Today, about one in three adults takes them.
However, a 2024 study published in Cell Metabolism suggests these drugs may quietly disrupt another part of the body’s metabolism. Patients on atorvastatin, one of the most common statins, saw their levels of GLP-1—the hormone mimicked by Ozempic and other weight-loss drugs—drop by nearly half.
The finding suggests that while statins lower cholesterol, they may also nudge metabolism in the opposite direction, raising blood sugar and weight, both key drivers of heart disease. Early evidence hints the effect might be reversible with a simple supplement, yet the discovery has barely touched medical training or patient care.
The Study
In the randomized controlled trial, 30 people starting atorvastatin were tracked for four months alongside 10 controls. Cholesterol fell as expected, but blood sugar edged up, insulin resistance worsened, and GLP-1 levels plunged by nearly half.
Researchers traced the mechanism to the gut. Statins reduced Clostridium bacteria, which make a bile acid called UDCA. That bile acid normally helps the body produce GLP-1. With fewer microbes, UDCA fell—and so did GLP-1. In other words, statins disrupted a microbial pathway that helps the body regulate blood sugar.
“With sets of experiments the researchers used, they make a very convincing case for that connection,” Dr. Adrian Soto-Mota, a physician-scientist who studies metabolic disease, told The Epoch Times in an email.
Your calves are your “second heart”—neglect them, and the result can be deadly.
Doctors warn that weak calf muscles cause stagnant blood flow, fueling clots, deep vein thrombosis, and even fatal pulmonary embolisms.
Every step you don’t take forces your veins to fight gravity alone, raising the silent danger inside your body.
And the one-minute fix that protects this hidden heart? Almost no one is doing it.
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When we think of the cardiovascular system, the heart usually gets the credit for keeping the blood running through the 60,000 miles of vessels in the body.
However, behind the scenes, our calf muscles are also constantly contracting to return our blood flow upward, working against gravity, leading some experts to label the calf pump our “second heart.”
If you are not using your calf muscles, your heart and vascular system may suffer.
Reduced calf muscle pump function is a risk factor for blood clotting in the veins, which can lead to serious complications, including deep vein thrombosis and pulmonary embolism, according to a 2021 study published in the American Society of Hematology.
Dr. Sonja Stiller, a double board-certified physician and founder of the Center for Advanced Vein Care in Mentor, Ohio, described using the “second heart” metaphor for the calf muscles as a light-bulb moment for many of her patients in her quest to get them to “just move.”
Millions Taking Ibuprofen May Be at Serious Risk, Studies Show
Before you take your next dose, make sure you’re not in the danger zone.
For these five groups of people, ibuprofen poses serious health risks that outweigh potential benefits.
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Popping an ibuprofen for that pounding headache or twisted ankle can provide quick relief from pain.
But although this easily accessible over-the-counter drug could temporarily mask discomfort and sometimes eliminate pain, experts say it does little to spur true healing.
Furthermore, for these five groups of people, ibuprofen poses serious health risks that outweigh potential benefits.
The 3,000-Year-Old Secret Weapon for Anxiety, Inflammation, and Modern Mayhem
You’ve smelled it at church. Maybe even at yoga.
Now scientists are studying it for cancer, anxiety, arthritis, asthma, and irritable bowel—which, let’s be honest, covers most of the Western world over 35.
Turns out, frankincense isn’t just incense. It’s medicine.
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If you’ve never heard of Boswellia, don’t worry, you’ve definitely sniffed it. Or wafted it. Or had a minor spiritual epiphany while someone burned it at a yoga class that you regretted taking halfway through.
Boswellia is the tree behind frankincense, which is surprisingly relevant to your inflamed joints, anxious brain, or slightly dodgy bowel.
This squat little tree is found in dry, dramatic places like Oman, Ethiopia, and Somalia. The tree oozes a resin when cut, like sap.
People have been scraping, sniffing, and slathering this stuff on everything from bruises to bad moods for thousands of years. And I do mean everything.
The ancient Egyptians called it the “tears of Horus” (emotional much?) and used it in embalming and in incense burned during religious rituals. The Greeks burned it in temples. The Romans traded it like it was sandalwood-scented Bitcoin.
By the time the Wise Men were loading it onto a camel for a celestial baby shower, Boswellia resin was worth more than gold.
But here’s where it gets juicy.
It wasn’t just for incense and embalming and vaguely spiritual vibes. Boswellia was medicine.
Chagas disease is the silent killer no one is talking about.
UCLA doctors warn the parasite spread by “kissing bugs” can cause sudden death—or slowly destroy the heart over a lifetime.
The CDC reports that even common symptoms like fever or fatigue may hide a fatal infection.
With 45,000 cases in Los Angeles alone, why isn’t this national health crisis on every front page?
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Chagas disease, an illness transmitted by “kissing bugs,” is now considered endemic in the United States, the University of California–Los Angeles (UCLA) said in a Sept. 2 post, citing a recent report from the Centers for Disease Control and Prevention.
Kissing bugs—also known as conenose or barber bugs—transmit the parasite Trypanosoma cruzi to humans, which causes Chagas disease.