Aravind Palraj Profile picture
Oct 23 12 tweets 4 min read Read on X
🧵The best clinicians diagnose before the investigations arrive.

Here are 100 timeless history-taking gems from Hutchison’s Clinical Methods (25th Edition) — distilled into pure bedside wisdom.

🩺 This thread reminds us why the story still matters more than the scan 👇

(Bookmark this — it’ll shape your next patient encounter.)
@DrAkhilX @IhabFathiSulima @drkeithsiau @RheumNow @Janetbirdope #MedTwitter #MedEd #FOAMed #Medicine #internalmedicineImage
The Art of Beginning

1️⃣ The history starts before you speak.

Observe posture, mood, breathing, gait — the body always speaks first.

Then say softly:
“Tell me about your problem.”

Silence in the first 30 seconds is golden. Image
Chief Complaint

2️⃣ Always in the patient’s own words.

“I feel tired for 2 weeks” > “Fatigue × 2 weeks.”

Ask: “What troubles you most?”
The answer guides the whole consultation. Image
Pain

3️⃣ Pain has a story — location, radiation, character, severity, timing.

“Point with one finger.”

Sharp = somatic.
Dull = visceral.
Burning = neuropathic.

The pattern defines the pathology. Image
Fever, Fatigue, Weight Loss

4️⃣ Never skip constitutional symptoms.

Fever patterns whisper the diagnosis.

🔹 Evening fever → TB
🔹 Intermittent rigors → malaria
🔹 Night sweats → lymphoma

Weight loss? Always quantify it. Image
Cardiovascular

5️⃣ Chest pain, dyspnoea, palpitation, syncope, oedema.

The “Big Five” cardiac questions.

Ask:
“How far can you walk before breathlessness?”
That’s better than any NYHA class. Image
Respiratory

6️⃣ Cough and sputum are storytellers.

Color, quantity, timing.
Morning = bronchitis, nocturnal = asthma.

Haemoptysis?
“How much? Fresh or streaked?”
The words decide urgency. Image
Gastrointestinal

7️⃣ Appetite, nausea, vomiting, bowel, bleed.

Ask: “Any change in food taste or smell?”
(An early hepatic or uremic clue.)

Blood in stool → ask color first.
Black ≠ red ≠ same disease. Image
Genitourinary

8️⃣ Frequency, urgency, dysuria, hematuria.

“When in the stream do you see blood?”

▪️ Beginning → urethra
▪️ End → bladder neck
▪️ Throughout → renal

These 10 seconds save 3 tests. Image
Neurological

9️⃣ The nervous system whispers.

Ask for headache, vision, speech, weakness, sensation, balance.

“Any double vision?” → localizes before you touch a reflex hammer. Image
Musculoskeletal

🔟 Joint pain — site, symmetry, swelling, stiffness.

Morning stiffness > 30 mins → inflammatory.
Evening pain → mechanical.

Ask what the patient can’t do anymore.
That’s functional disability — Hutchison’s gold standard. Image
Integration & Insight

💯 Every symptom has a context.

Sequence. Duration. Progression. Impact.

“When did you last feel completely well?” — the most diagnostic question of all.

#MedTwitter #Hutchison #ClinicalMethods #BedsideMedicine #RheumRounds

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More from @Rheumat_Aravind

Oct 21
🧵100 timeless bedside gems every doctor should know.
Straight from Hutchison’s Clinical Methods — distilled into 10 clean infographics.

If you love real clinical medicine, this thread will remind you why you chose it.

🩺 Let’s bring back the art of examination 👇

(Save this thread — it’ll outlive most AI tools.) #MedTwitter #MedEd #FOAMed @DrAkhilX @IhabFathiSulima @drkeithsiau @DurgaPrasannaM1 @JasmineNephroImage
General Principles

1️⃣ The patient will tell you the diagnosis — if you learn to listen.

History first. Examination next. Investigations last.

🩺 The foundation Hutchison built 125 years ago still holds true. Image
General Inspection

2️⃣ The first 10 seconds matter.

How they walk, talk, sit, breathe — that’s your first set of vitals.

The best clinicians diagnose before touching the patient. Image
Read 12 tweets
Sep 28
🧵 DADA2 & Vasculitis — The Hidden Culprit

1/
What if one mutation causes vasculitis, strokes, immune deficiency & cytopenias — all in one patient?
That’s DADA2 (Deficiency of Adenosine Deaminase 2).
@DrAkhilX @IhabFathiSulima #MedTwitter #RheumTwitter Image
2/
🔍 What is DADA2?
•Rare, autosomal recessive disease
•Mutations in ADA2 gene → enzyme deficiency
•Impacts vessels, immune system, bone marrow Image
3/
⚡ Vasculitis hallmark
•Inflammation, stenosis, occlusion of small/medium vessels
•Often mimics Polyarteritis Nodosa (PAN) Image
Read 10 tweets
Sep 24
🧵 Management of Scleroderma (Systemic Sclerosis) – 2025 Update

1/
Scleroderma (Systemic Sclerosis, SSc) is a chronic autoimmune connective tissue disease with fibrosis, vasculopathy, and autoimmunity at its core.
Management is organ-specific and evolving with new evidence. Let’s break it down. 👇
@DrAkhilX @IhabFathiSulima #MedTwitterImage
2/
🔹 General Principles
•No single “cure” exists.
•Approach is multidisciplinary: rheumatology, pulmonology, cardiology, nephrology, dermatology.
•Early recognition of organ involvement = better outcomes. Image
3/
🌿 Lifestyle & Supportive Care
•Smoking cessation
•Physical therapy & hand exercises
•Skin care (moisturizers, avoid cold exposure)
•Vaccinations (flu, pneumococcal, COVID)
•Patient education + psychosocial support
Read 12 tweets
Sep 24
🧵: Proteinuria – When to Think Beyond the Kidneys

Tweet 1:
Proteinuria isn’t always just nephrology.
Sometimes, it’s the first clue to systemic disease.
Here’s how to approach proteinuria with an internal medicine + rheumatology lens 👇 @DrAkhilX @IhabFathiSulima #MedTwitter #RheumTwitter #NephroTwitterImage
Tweet 2:
🔍 Step 1: Confirm proteinuria
•Dipstick vs. spot UPr/Cr ratio vs. 24h collection
•Rule out false positives (alkaline urine, hematuria, concentrated sample) Image
Tweet 3:
📊 Step 2: Quantify
•<500 mg/day → often tubular or overflow causes
•0.5–3.5 g/day → non-nephrotic, think secondary causes
•3.5 g/day → nephrotic, raises red flags for glomerular pathology Image
Read 7 tweets
Sep 24
🧵 : Shortness of Breath – When is it Rheumatology?

Tweet 1:
Shortness of breath (SOB) isn’t always cardiac or pulmonary.
Sometimes, the cause is hidden in the immune system.
Here’s how to separate Medicine vs Rheumatology causes 👇
@DrAkhilX @IhabFathiSulima @CelestinoGutirr #MedTwitter #RheumTwitter #PulmoTwitterImage
Tweet 2:
📌 Internal Medicine causes (common):
•Heart failure
•COPD/asthma
•Pneumonia
•Pulmonary embolism
•Anemia

(Always rule these first.) Image
Tweet 3:
📌 Rheumatology causes (often missed):
•Interstitial lung disease (RA, SSc, MCTD, myositis)
•Pulmonary hypertension (SSc, SLE, MCTD)
•Pleuritis / pericarditis (SLE)
•Diffuse alveolar hemorrhage (ANCA vasculitis, SLE)
•Shrinking lung syndrome (rare SLE) Image
Read 6 tweets
Sep 23
🧵 Approach to Recurrent Fever – Don’t Miss These Clues

Tweet 1:
Recurrent fever is a diagnostic puzzle.
Is it infection, malignancy, or autoimmunity?
Here’s a structured approach every clinician should know 👇
@DrAkhilX @IhabFathiSulima #MedTwitter #RheumTwitter Image
Tweet 2:
📌 Step 1: Define it
•Recurrent fever = fever episodes with return to baseline in between.
•Different from persistent FUO.
•History of pattern (daily, cyclical, periodic) is vital. Image
Tweet 3:
📌 Step 2: Broad buckets
1.Infections (TB, occult abscess, endocarditis).
2.Malignancy (lymphoma, leukemia).
3.Autoimmune/Autoinflammatory (SLE, Still’s disease, vasculitis, FMF, TRAPS).
4.Miscellaneous (drug fever, factitious). Image
Read 7 tweets

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