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tern Profile picture
@1goodtern
Oct 25, 2025 • 46 tweets • 9 min read • Read on X
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How's that lymph system doing.
Blastic NK-cell lymphoma, England. Image
Blastic NK-cell lymphoma means something has gone *really wrong* in immune regulation.
It’s a malignancy of the cells that are *supposed to destroy infected cells*.
NK cells - "natural killer” cells - are the immune system's first-strike unit.
They're the ones that find and kill virus-infected cells before antibodies even show up.
If you start seeing more NK-cell cancers, something’s driving chronic activation and mutation inside that system.

Something up here. Image
Now, think about Covid infection:
Every infection triggers a massive NK-cell surge.
Those cells get overstimulated, exhausted, and sometimes permanently altered.
Post-COVID studies show lingering activation markers, basically, NK cells stuck in attack mode for months.
That means they keep dividing...
Keep generating oxidative stress...
Keep collecting DNA damage in a high-inflammation environment...
And all that while the repair pathways (like p53) are being suppressed (by cytokines like IL-6 and TNF-alpha).
At the same time, the immune brakes are off.
T cells are depleted and exhausted.
Interferon signalling is blunted.
So when an abnormal clone of NK cells appears, the immune system doesn't clear it. *It lets it grow*.
Add to that the reactivation of latent viruses (EBV, CMV, HHV-6) all known to cause NK/T-cell malignancies...
COVID reawakens them, repeatedly.
Each reactivation wave means another round of inflammation and oxidative stress and immune dysregulation.
The problems aren't just in adults... there's stuff going on in kids too. Image
So you end up with this:
A system of immune cells pushed to divide too often,
mutating in an inflamed environment,
with the tumour-suppressor side of immunity switched off.
And from that, you get what we’re seeing here. A surge in blastic NK-cell lymphoma.
I wonder what else is going on in that lymph system...

Oh boy.
😮 Image
Oh boy. Image
Oh boy oh boy Image
Erm.
👀 Image
👀 Image
👀 Image
👀 Image
And then strange things going on with other aspects of the immune system... Image
And this running away... Image
And then damage to all that lets this kind of damage loose... Image
And that this... Image
Hmm.
Those gut infections are really exploiting something these last four years, aren't they... Image
Oh my word. Image
👀 Image
This is all just nuts. Image
This damage is in adults, kids, infants, everywhere. Image
It's in these kind of diseases where the end result is scarring of internal organs after immune hyperactivation:

This is in KIDS AGED 0 to 9. Image
You might expect this to pop up as a result of immune dysregulation in the gut... Image
Oh boy. Image
What the what. Image
What does inflammation in the brain cause... Image
More tomorrow... this list is long.
Maybe a few more... Image
👀 Image
👀 Image
This is in *kids*
👀 Image
This is in *young adults* 👀 Image
flip. Image
Nothing to see here, just a doubling of TUBERCULOSIS OF BONE. Image
Oh dear. Image
Hmm.
I didn't expect so many people to read this thread, or I would have included a bit like this, explaining that not every condition is rising like that...
@PetersCynthia There's 9,000 charts in the database, it's hard to even view them all, let alone post them!

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More from @1goodtern

tern Profile picture
Apr 15
Look:
There is no such thing as overdiagnosis.

There is just diagnosis (correct) or misdiagnosis (wrong).

If a diagnosis is correct, then you can't have too much of it.
If there's any incorrect diagnosis, then it's a misdiagnosis.
So you can't have 'too much diagnosis'.

It's like saying something is too appropriate.
Read 50 tweets
tern Profile picture
Apr 15
Trigger warning.
It takes a while for this disgusting article to reach its point, but when it does, it does it with so much callousness and wanton cruelty.

"Long Covid – the disease that started as a hashtag"

No, you hideous ghouls, it starts as covid infection. Image
On 2020:
"it’s inescapable that the period was a melting pot for psychosomatic conditions."

Yes, that would be what killed that quarter of a million people, and hospitalised one and a half million people. Psychosomatic conditions.
Ffs. This doctor that "stresses she isn’t dismissing suffering" literally dismisses the suffering caused by covid infections.
Read 21 tweets
tern Profile picture
Apr 8
So it's now recognised that Long Covid is probably costing the world economy about a trillion a year in lost productivity.

You're reading that right.

So what should we do about it.
1) Reduce new infections by reducing transmission.

A) Clean the air in every public space now.

This is far easier than it sounds:
CHUMV (you can say it Chumvee):
CO₂ monitoring
HEPA
UV
MERV
VENTILATE
Read 21 tweets
tern Profile picture
Apr 8
Here's a quick personal story.

Twenty something years ago, I picked up a mystery infection that hammered my system and left me with all sorts of health problems.
I'll come back to some of those bits in a mo, but here's the point of the story:

After a while, I discovered that I'm ok with exercise as long as it's a very small increase of something that I'm used to.
(this is not an 'all you need to do to get better is exercise' thread, and it's not a prescription of exercise to people with any chronic illness, I'll explain that more later too)
Read 38 tweets
tern Profile picture
Apr 6
I did an experiment two weeks ago.
I posted a request in two very similar fb groups, asking for advice in one on how to support 'someone with Long Covid', and in the other 'someone with a complicated post-viral condition'.

Four observations about the replies:
Fewer people engaged with the long covid one.
The replies that were made to the long covid post were less sympathetic, even though the description of the symptoms was word for word the same.
Read 11 tweets
tern Profile picture
Apr 2
When you have a chronic health condition, it can be hard to explain to people without a chronic health condition what it means.
You say, "I have muscle pain", and they say, "oh yes, I did the London marathon and all my muscles hurt for two days".
You say, "I can't sleep", and they say, "oh yes, I was out at a concert last night and didn't get home until two. I only had five hours".
Read 17 tweets

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