Them: But if Covid infections lower your lymphocytes wouldn't more people be dying from infections??

Me: Yes, that's right, that's exactly what's happening. 👇 Also them: But those people are probably just weak and old. Surely we'd also see some kind of increase in sickness among healthy young people, specifically from infections?

Me: Yes, that too 👇

Why don't people grasp how serious this is?

Across an entire population, losing more than three years of your healthy life expectancy...

That is just staggering.

Especially because of this: The big problem is that it *isn't even distributed evenly*.

This one should be labelled 'Public Health Failure'.

https://twitter.com/1goodtern/status/2028839410674938048

Yep, I've taken funerals for two of these.

What are people dying from?
How do those causes of death change from year to year? We have a big database here in England that helps catalogue causes of death. The most recent version is for the year 2024.

People don't understand that there are several real models of cumulative harm that apply to covid infections.

People don't like complex ideas, so they avoid them.

This is going to be a long thread, with several simple ideas that combine to make a big complex one. First off, we *know* beyond all doubt that covid infections cause short term harm.

Do midwives know that they're now twice as likely to be off sick with a pregnancy related disorder than before the Covid pandemic started? Do nurses?
And health visitors?

I think one of the most important conclusions people are missing from the data in the recent big studies is that covid infections cause radically diverse long term effects in different age groups. So much so that it could appear as if they've been infected with different viruses.

Okay folks, I'm calling it, and it's bad news:

The word mucinous is going to become much more common.

Yes, bookmark this tweet, it looks bland, but it's important. oh, okay. I won't leave you hanging.

I've written a lot recently about how we're missing the big picture of how covid infection is doing cumulative damage to interfaces in the body - linings, membranes, barriers, walls, filters.

I know, I know, you're going to laugh at me for saying that you're more likely to have problems with cramp after you've had a covid infection, but it's all very simple science. Loads of people have been mentioning cramp recently, and like so many other conditions, yes, covid infection makes it more likely, and makes it worse.
It's just an extra factor on top of all the normal factors for cramp.

Do you know which whacky loons say that covid infections increase the risk of heart disease?
The British Heart Foundation. Do you know which antivaxers say that covid vaccines do not fully protect against infection, illness, or long term effects?
Pfizer.

⚠️
The three subtle warning signs that everyone's missing: 1
All of the people asking "why is everyone sick all the time now?"

A couple of very important studies out just in the last 24 hours confirming what we've been saying for years and years now: Covid infections affect your immune system *badly*.
Here's a few things you may have missed in them. This is almost entirely post vaccination data
This is not an unprotected population.
Baseline immune measurements come from a period when vaccination coverage was already high, and the immune damage appears *after mass infection*.

You're not going to like the next tweet in this thread, so don't read it. I don't think there's a difference between the set 'people who have had a covid infection' and 'people who have long term effects from a covid infection'.

This may be obvious to everyone else already, but it occurred to me today that ICE just does not have the manpower to do everywhere what it's doing in Minnesota.

The surge there is not sustainable nationwide. But the appearance of ICE being everywhere right now is heavily shaped by the unusually large and concentrated deployment in Minnesota, which is drawing outsized attention and resources.

One of my dissertations was on the causes of the second world war.

I wrote it late, in a hurry, when I was young, naive, sleep deprived, and thought that it was ancient history.

But one aspect of what I wrote was what Germany looked like *from the outside*.
🧵 Here are six key views of Germany from other countries at the time that totally misread the situation.

Some of them might be relevant today.

Just imagine for a moment that you are infected with a virus that harms the lining of your arteries. The virus doesn't damage the artery walls in every part of your body to exactly the same degree. Some parts will be more damaged, some less.

At your next infection, will the parts of your artery wall that were more damaged first time round be more or less vulnerable to the virus? It's an interesting question, isn't it.

Will those damaged parts be better equipped the next time round?

I just want to do a very quick run through the latest up to date charts of rates of sickness absence in *young* doctors here.

Yeah. This is still *really* important, and I'll explain why in a moment. There are some really really important points before I get on to the graphs.

Let's play "Guess Where The Line Goes"

This one is "Retirement Due To Ill Health, NHS England".

It's a horrible thing to be playing games with, but I think it's less horrible to play 'Guess Where The Line Goes' than to ignore it altogether. A, B, C, or D?

The minimisers would have you believe that every bad health condition develops immediately, symptoms of it appear immediately, medical attention is found immediately, and the condition is diagnosed immediately.

The truth is very different. It can take years for conditions to develop after they have been triggered.

I've been kicking around the acronym cii.

Covid Infection Induced.

For example: cii cognitive dysfunction
cii memory impairment
cii executive dysfunction
cii brain fog
cii attention deficit
cii encephalopathy
cii encephalitis
cii seizures
cii new onset epilepsy
cii migraine
cii chronic daily headache
cii anosmia
cii hyposmia
cii ageusia
cii dysgeusia
cii tinnitus
cii hearing loss
cii vestibular dysfunction
cii dizziness
cii vertigo
cii sleep disturbance
cii insomnia
cii hypersomnia
cii circadian rhythm disruption
cii dysautonomia
cii postural orthostatic tachycardia syndrome
cii inappropriate sinus tachycardia
cii orthostatic hypotension
cii blood pressure instability
cii temperature dysregulation
cii sweating disorders
cii heat intolerance
cii exercise intolerance
cii post exertional symptom exacerbation
cii chronic fatigue
cii myalgic encephalomyelitis
cii post viral fatigue syndrome
cii severe deconditioning
cii sarcopenia
cii anxiety disorder
cii depressive disorder
cii mood instability
cii panic disorder
cii post traumatic stress disorder
cii myocarditis
cii pericarditis
cii myopericarditis
cii arrhythmia
cii atrial fibrillation
cii ventricular ectopy
cii heart failure
cii reduced ejection fraction
cii microvascular angina
cii endothelial dysfunction
cii vascular inflammation
cii arterial stiffness
cii thrombosis
cii pulmonary embolism
cii deep vein thrombosis
cii microclot disease
cii hypercoagulability
cii reduced lung capacity
cii restrictive lung disease
cii obstructive lung disease
cii pulmonary fibrosis
cii chronic cough
cii dyspnoea
cii hypoxia
cii impaired gas exchange
cii immune dysregulation
cii immune exhaustion
cii lymphopenia
cii neutrophil dysfunction
cii impaired interferon response
cii impaired opsonisation
cii reactivation of latent viruses
cii frequent infections
cii vaccine hyporesponsiveness
cii autoantibody production
cii autoimmune disease onset
cii autoimmune disease flare
cii sjogren’s syndrome
cii rheumatoid arthritis
cii systemic lupus erythematosus
cii vasculitis
cii antiphospholipid syndrome
cii autoimmune thyroid disease
cii type 1 diabetes
cii mast cell activation
cii histamine intolerance
cii anaphylactoid reactions
cii new food sensitivities
cii drug hypersensitivity
cii gastrointestinal dysmotility
cii gastroparesis
cii chronic nausea
cii chronic diarrhoea
cii constipation
cii abdominal pain
cii irritable bowel syndrome
cii inflammatory bowel disease flare
cii malabsorption
cii altered gut microbiome
cii liver injury
cii elevated transaminases
cii fatty liver disease progression
cii cholestasis
cii pancreatic dysfunction
cii pancreatitis
cii impaired insulin secretion
cii insulin resistance
cii new onset diabetes
cii kidney injury
cii chronic kidney disease progression
cii proteinuria
cii haematuria
cii bladder dysfunction
cii urinary frequency
cii urinary urgency
cii incontinence
cii sexual dysfunction
cii erectile dysfunction
cii menstrual irregularity
cii amenorrhoea
cii ovarian dysfunction
cii reduced fertility
cii endothelial barrier damage
cii blood brain barrier disruption
cii gut barrier permeability
cii vascular leak
cii musculoskeletal pain
cii myalgia
cii arthralgia
cii inflammatory arthritis
cii connective tissue fragility
cii skin disease
cii chilblain like lesions
cii vasculitic rash
cii urticaria
cii hair loss
cii eye disease
cii dry eye
cii uveitis
cii retinal vascular injury
cii visual disturbance
cii accelerated ageing
cii frailty
cii reduced physiological reserve
cii increased all cause mortality

I think we've let the damage that covid infections do to *linings* slip into the background of all the other problems that covid infections cause.

I think this may be a *big* problem. Across all of these, the pattern is the same: structural cell loss is followed by repair that restores structural continuity but not precision of purpose.