1/9: Did you know your body has a built-in defense system against blocked arteries? It's true! High-Intensity Interval Training (HIIT) is scientifically proven to enhance your heart's "backup highways," known as coronary collaterals, offering significant protection against heart damage.
2/9: What are Coronary Collaterals? They are alternative circulatory pathways that provide crucial backup blood flow when main coronary arteries become narrowed or blocked. They don't appear suddenly; they are small, pre-existing vessels (30-50 µm) that remodel and enlarge through a process called arteriogenesis.
3/9: How does HIIT build these "backup vessels"? The primary trigger is increased fluid shear stress. When you perform intense exercise, your heart rate and cardiac output surge, forcing blood through these tiny collateral vessels. This pressure signals the vessel walls to remodel, grow, and become larger bypass routes.
4/9: Collateral development isn't instant. While some changes occur early after an acute event, exercise-induced growth requires sustained training over weeks to months for optimal adaptation. Training also helps maintain a delicate "redox window", the perfect level of oxygen stress needed for vessel growth and remodeling.
5/9: Why choose HIIT over standard moderate exercise (MICT)? HIIT is significantly superior at boosting your peak oxygen consumption (VO₂peak)—the most important measure of cardiorespiratory fitness. HIIT increases VO₂peak by about 2.11 mL/kg/min more than MICT in heart disease patients. The biggest advantage: time efficiency. You can achieve superior results in less time.
6/9: The Protocol: The most studied and heart-safe regimen is the "4x4 Method" (or The Norwegian Protocol).
It looks like this: 1. 4 minutes at high intensity (85-95% of max heart rate) 2. 3 minutes active recovery (about 70% HRmax) 3. Repeat the cycle 4 times.
7/9: Is High-Intensity training safe for heart patients? YES, when supervised. Systematic reviews show HIIT has a very low rate of adverse events. One analysis found only 1 major cardiovascular event per 17,083 training sessions. HIIT is well-tolerated and comparable in safety to moderate exercise, especially in stable patients.
8/9: The clinical impact of HIIT is huge: Beyond building collaterals, HIIT acts like "ischemic preconditioning," making the heart muscle more resistant to damage if a blockage occurs.
This is a vital strategy, particularly for the 25–30% of patients who cannot undergo complete surgical revascularization.
9/9: Summary & Takeaway: HIIT is a powerful, science-backed therapy that rebuilds your cardiovascular resilience through multiple pathways (collateral growth, reduced inflammation, improved vessel function).
To maximize collateral benefits, aim for training at least 3 times per week for a minimum of 4–8 weeks.
Always seek medical clearance and professional supervision before starting an intense exercise program.
Thanks for reading.
#HIITforHeartHealth
#NaturalBypass
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Ever wondered why does it take so long for a vaginal delivery to occur?
If nature wanted it could have delivered babies instantly, without the morbidity and mortality of both babies and mothers.
But there are issues which needed to be fixed by the evolution...
Why Human Labour Takes So Long? A Full Scientific Yet Simple Explanation:
Basic evolutionary changes : 1) The price of walking on two legs instead of 4 was smaller pelvis aka bony birth canal in human female. 2) Humans evolved large brains, which means babies have big heads, among the largest (relative to body size) in the animal kingdom.
3) Twisted Birth Route:
Unlike most mammals, human babies must rotate their heads inside the birth canal. It’s a complex corkscrew motion, not a straight path. 4) Hormones Prepare Gradually:
Labour is not just mechanical. It is a beautiful and wellcoordinated symphony of chemicals and physical forces, well mostly. Hormones like oxytocin, prostaglandins, and relaxin work together to soften the cervix aka the opening to the uterus, coordinate contractions, and relax pelvic ligaments. This biochemical and physical orchestra takes time to warm up.
The house always wins. But people still gamble. Here’s why logic doesn’t stand a chance against hope, dopamine, and illusion 👇
Gambling is not about maths.
It’s about emotion.
Even with a fixed 2–5% house edge, people still bet.
Why? Because somewhere deep down, we believe:
“Someone has to win. Why not me?”
The illusion of control
Gamblers think they can beat the system.
Spot patterns. Time the wheel. Use “strategies.”
In truth, they’re just dancing with randomness which presents as hope.
1/n Cancer is basically when normal body cells go rogue—dividing endlessly instead of following the body’s disciplined checks and balances.
So, the more cells an animal has, and the longer it lives, the more chances for things to go wrong.
2/n This is why taller humans and larger dogs are known to have higher cancer risks.
More body = more cell divisions = more chances for mutations.
So big animals like whales or elephants should have a lot more cancer.
But they don’t.
3/n This contradiction is known as Peto’s Paradox, named after epidemiologist Richard Peto, who noted that cancer rates don’t increase with body size across species.
Despite being enormous and long-lived, elephants and whales have surprisingly low cancer rates.
🧵 THREAD: Sovereign Gold Bonds - From Brilliant Innovation to Fiscal Disaster 1/ Sovereign Gold Bonds (SGBs) were launched in 2015 as a genius alternative to physical gold ownership in India. Today, they’re considered one of the costliest policy mistakes in recent financial history. Here’s the fascinating story…
2/ SGBs 101: Government securities denominated in grams of gold, paying 2.5% annual interest PLUS the appreciation in gold value, with tax-free capital gains at redemption. Sounds too good to be true? Well, for investors it wasn’t - for the government, it was a disaster.
3/ The fatal flaw? The government essentially took a massive SHORT position on gold without hedging. They bet gold prices wouldn’t rise significantly over 8 years.
Spoiler alert: gold prices SURGED.
Thread: Investment returns aren’t lies — but they often wear makeup.
CAGR, XIRR, IRR, TWRR… it’s easy to get confused and impressed by numbers.
A simple guide to understand returns — and how different assets cherry-pick the one that flatters them most….
1. Simple Return (a.k.a. Absolute Return)
It’s just the total % increase.
You buy at ₹10L, sell at ₹30L — return is 200%.
Simple. But it says nothing about time.
200% over 2 years? Great.
Over 20 years? Meh.
Used by: Real estate, gold…..
2. CAGR (Compounded Annual Growth Rate)
This shows how much you made per year, assuming steady growth.
Buy at ₹10L, sell at ₹30L in 10 years → CAGR ≈ 11.6%
Now you can compare it to FDs, mutual funds, etc.
Used by: Mutual funds, equity fans, long-term investors…
1/ I’ve noticed a dramatic shift. Modi’s supporters are no longer singing praises of him or his policies. Here’s why: stagnant salaries, rising unemployment, inflation, and a shrinking middle class. 🧵
2/ Leading FMCG companies admit discretionary spending is down. Corruption is rampant. We’re left with polluted air, water, and food. Housing is unaffordable. And there’s zero focus on improving our greatest asset: human capital by focusing onhealthcare & education.
3/ Instead, the focus is on religion, hyper-nationalism, and claiming India is a vishwa guru. Meanwhile, we rely on China for raw materials critical to MSMEs—the backbone of our economy.