tern Profile picture
Nov 13 22 tweets 5 min read Read on X
Three quick things about this year's flu wave. Image
Has it actually 'kicked off' yet?

Look at 2019 and 2024.
They have one kicking off point.

Interestingly it was the same week in both years - the week kids go back to school after half term break.

From there it skyrockets. Image
2022 in Orange kind of has two gears.
It starts off at a steady pace in August, then goes into afterburners in mid-November.

(2023 starts later in the year, but still changes gear in November) Image
2025 kinda follows 2022's pattern a little to start - with the early growth ahead of 2019 or 2014, but a bit more aggressively than 2022.

The question is... is it about to change up into another gear? Image
Because if it *does change up*, that's an even higher base to be starting from.
And as I've said elsewhere, don't be fooled by the slight apparent slowing in the last week.
Other years do the same thing before going into orbit during this second half of term.
But meanwhile, in the background, RSV is also doing *the same thing* that it did in 2022.
Leaping from nothing to lots in just a week.
It's already at 40% of the flu healthcare attendances in *just one week of growth*. Image
So... the ukhsa are talking about 'RSV at baseline levels', but they're doing that while looking at goofy charts like this one. Image
I don't think they're going to get a sense of urgency until it's too late.
RSV slammed in alongside flu in 2022 on the back of a summer of Covid.

I expect it to do exactly the same thing this year.
But going back to this one... there's an advantage and a danger to this graph that compares the different years.

By putting them all on one graph, your brain kind of looks at the outer edge of the whole block. Image
Image
So unless you're deliberately directly focussing on the individual years, you just kind of see a mass of years together - in that sense it's good to be able to see the outer edge of the shape.
But it's not very good for comparing it to the shape of *individual* years.
So here it is compared with the big 2022 flu wave.

Let's hope that this one doesn't accelerate the same way. Image
Compared with 2019, pre-pandemic.

Do you see that this wave has two gears too?
One slight growth through the first half of term, then the acceleration after? Image
2023 hit much later.

Honestly, I hope that this one follows the same pattern and doesn't leap from this point. Image
And here's last year.

It was at this point, the first week of November, when things took off last year. Image
The next two weeks will provide a massive clue as to what will happen over the next two months.
But it's not just about the height of the peak.

Which of these two has more area 'under the line'?

Yeah. It's a little bit hard to tell.

But actually it's 2024.

Last year was a *worse* flu year than 2022. Image
So 2022 put healthcare under more pressure over a short period, but 2024 made more people ill overall.
And that's the big concern about the wave going early.

Is it going to stay high for a longer period?

Once Flu A has had its wave, are we going to get a Flu B tail like last year?
Yep.
We'll find out the hard way.

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More from @1goodtern

Nov 12
I've been sent the text below, which is an extract from a proposed article that didn't make it to publication.
The writer asked me to share it.

For American readers: categories like Motor Neuron Disease include things like Amyotrophic Lateral Sclerosis/ALS/Lou Gehrig's disease. Image
"There is growing concern among clinicians and researchers that COVID-19 infection may be contributing to a striking rise in rare but serious neuromuscular conditions such as motor neuron disease (MND) and spinal muscular atrophy (SMA) among younger adults.
While these disorders are typically regarded as genetic or idiopathic, mounting evidence suggests that viral infections...
Read 12 tweets
Nov 11
I've been watching soccer players here get ACL injuries with painful regularity over the last five years.

I've had two ACL injuries myself, and some times of year I develop a painful ache just below and to the side of my knee that feels like a small ball of pure pain.
🧵
So whenever I hear about someone going through this, I feel a strong personal empathy.
I know what it's going to be like for them to try to sleep tonight, and how they'll feel when they try to roll over.
Read 35 tweets
Nov 11
You might think that public health bodies and institutions and their leaders know what they're talking about, but, sadly, they often just regurgitate garbage fake science that has no actual basis in fact, but sometimes it's more sinister than that.
Here's an example, shared a couple of weeks ago by the American Society of Microbiology.

It includes a claim (a lie, actually, but we'll come to that) that you might have seen repeated a lot during the last few years. Image
The *lie* that "80% of all infectious diseases are passed by human contact, direct or indirect".
Read 53 tweets
Nov 10
I'm slowly working my way through the thousands of conditions covered by the uk hospital episodes data.

Quite a few people have been asking me about POTS and Dysautonomia.

Well...
Where shall we start.

Autonomic nervous systems in teenagers? Image
👆That one was a catch all code covering disorders with overlapping sympathetic and parasympathetic dysfunction, post-viral or inflammatory dysautonomia, autonomic failure associated with another systemic disease, mixed or multi-system dysautonomia.
Read 17 tweets
Nov 10
I think it's worth taking a look at the trends in hospital episodes for breast cancer.
🧵
A few graphs to follow.
They show the number of 'hospital episodes' for different aspects of breast cancer.

Hospital episodes are *not the same* as case numbers, or people suffering from breast cancer.
But 'hospital episodes' are a very important tool to monitor changes in prevalence of conditions.
Read 45 tweets
Nov 10
If Covid infections caused harm to the immune system like weakening immune surveillance and dysregulation of T cell balance, making it harder to keep old viruses in check, then you'd expect to see some things.

Things.
🧵
You'd expect dormant infections to flare up again.
You'd expect more shingles, more EBV activity, maybe even more HPV-related disease...
Read 22 tweets

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