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Emmanuel Profile picture
@ejustin46
Nov 15 • 5 tweets • 2 min read • Read on X
A DANGEROUS H3N2 AND SARS-COV-2 COCKTAIL?

There's a French saying, "It’s no use being right if you’re the only one who believes it." Regarding H3N2, which is spreading rapidly, we've sounded the alarm multiple times. However, perhaps discussing it too early is of little value 😏 Image
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5) Thanks for reading 🙏

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More from @ejustin46

Emmanuel Profile picture
Nov 15
**MERS: The Forgotten Virus**

I have always been wary of this virus, perhaps because it belongs to the coronavirus family. Despite its significance, it rarely makes headlines. Over the past three years, there have been 2,658 reported cases, resulting in 958 deaths ... Image
2) ...figures that only reflect confirmed cases.

So why should we remain cautious about MERS? This megathread aims to provide some answers. ecdc.europa.eu/en/publication…Image
3)
Read 7 tweets
Emmanuel Profile picture
Nov 12
"Understanding Viral Evolution: The Shift and Drift Dynamics of Influenza and SARS-CoV-2"
(2nd part)

Antigenic drift and shift are key concepts in virology, particularly for influenza and SARS-CoV-2. Image
2) Drift refers to small genetic mutations over time, while shift involves major changes, often through reassortment.
For instance, seasonal flu viruses undergo drift, leading to new strains each year. In contrast, SARS-CoV-2 exhibits drift but ... Image
3) ...infrequently undergoes shift, making it relatively stable compared to influenza.
Recent research highlights that shift for coronaviruses, like SARS-CoV-2, can occur through recombination with other coronaviruses, such as MERS-CoV. Image
Read 5 tweets
Emmanuel Profile picture
Nov 12
"NEW FLU VIRUS MUTATION could see WORST SEASON in a DECADE"

Insights for understanding SARS-COV-2 (1st part) 🤔
Thanks to @mryoung151
for the article bbc.com/news/articles/…
2) Let's start with an overview of this article.
A newly mutated H3N2 influenza virus strain has emerged unexpectedly during summer, raising concerns about a potentially severe flu season, possibly the worst in a decade. Image
3) This strain's mutations, linked to an antigenic shift, enable it to evade existing immunity and increase its spread, with an estimated R of 1.4. Though the current flu vaccine may offer limited protection, health officials emphasize the importance of antiviral treatments and.. Image
Read 5 tweets
Emmanuel Profile picture
Nov 11
But WHO ARE ALL THESE DEAD PEOPLE that NO ONE is TALK ABOUT?

Imagine if every day in Europe, three or four planes carrying 180 passengers each were to crash, leaving no survivors, and yet no one talked about it. This troubling silence isn't just a European phenomenon; Image
2) it extends to many countries around the globe.

Looking back at the period from 2015 to 2019, the European community recorded about 5 million deaths each year—a figure that, while varying slightly depending on the sources, remained relatively stable. Image
3) However, during the three major pandemic waves from 2020 to 2023, the death toll surged, indicating a significant excess mortality (the difference between reported deaths and expected deaths). Image
Read 8 tweets
Emmanuel Profile picture
Nov 9
The FUNNEL of ESCAPE : Unlocking the Secrets of SARS-CoV-2 Survival !

An explanation for Kids 👩‍❤️‍👨based on this recent study :
"Constrained Evolutionary Funnels Shape Viral Immune Escape"
biorxiv.org/content/10.110…Image
2) In this study, scientists are trying to understand how tricky viruses, like the one that causes COVID-19, try to escape from our body's defenses.

**The Virus and Our Immune System:**
- Viruses are sneaky and always want to find new ways to avoid being caught ... Image
3) ... by our immune system (the body's defense system). Think of it like a character in a game that needs to avoid traps and heroes trying to catch them. Image
Read 10 tweets
Emmanuel Profile picture
Nov 6
**THE AGE OF PANZOONOTICS**

In the world of infectious diseases, panzoonotic diseases stand out for their ability to spread between multiple animal species and from animals to humans, revealing our interconnectedness.

What MAKES COVID-19 a UNIQUE PANZOONOTIC? Image
2)To grasp this, we must acknowledge the major panzoonotics that have influenced public health: Rabies (spanning 190 species) , COVID-19 (58 species), and avian influenza (48 species).
While COVID-19 is prominent, other diseases ...
3)... like Ebola or Zika illustrate this complex transmission. Bacterial panzoonotics, such as brucellosis or leptospirosis further emphasize the diverse threats we face. Image
Read 17 tweets

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