CardiovascularCorner Profile picture
Mar 11 11 tweets 4 min read Read on X
1/
Most people think you need an angiogram to detect coronary artery disease.

But sometimes, the first clue appears on a simple echocardiogram.

Here are echo findings that quietly reveal coronary artery disease (CAD), even before other tests. 🧵 Image
2/
In CAD, the first thing echo helps us look for is regional wall motion abnormalities.
When a coronary artery can't deliver enough blood, the affected myocardial segment stops contracting normally.
This is often the earliest visible sign of ischemia. Image
3/
Cardiologists classify wall motion using a simple scoring system:
◼️Normal / hyperkinetic
◼️ Hypokinetic (reduced contraction)
◼️ Akinetic (no contraction)
◼️ Dyskinetic (paradoxical motion)
This forms the basis of the Wall Motion Score Index (WMSI) used in ischemia assessment Image
Image
4/
Modern echocardiography goes beyond just "looking."
With speckle-tracking strain imaging, we can measure myocardial deformation and detect subtle dysfunction, even when the wall motion still appears normal.
Sometimes strain detects ischemia earlier than the eye can. 2D speckle tracking on the apical two-chamber view showing a significant decrease of longitudinal strain within the basal inferior wall (yellow segment, arrow) with a clear post-systolic deformation (arrow) on the yellow curve from the same segment.
5/
One interesting marker is post-systolic shortening (PSS).
Normally, the myocardium finishes contracting before the aortic valve closes.
But ischemic segments may contract late, after systole.
That delayed contraction can be a clue to ischemia. Characteristic longitudinal strain patterns of a normal myocardial segment (dashed line) (A), a segment with decreased peak systolic strain and evidence of postsystolic shortening, most likely due to active contraction (B), and a segment with systolic lengthening and postsystolic shortening (C) most likely caused by passive recoil in a segment that is potentially scarred. AVC, aortic valve closure; ECG, electrocardiogram
6/
Another powerful parameter is Global Longitudinal Strain (GLS).
Normal GLS is around −20%.
Less negative values often indicate impaired myocardial function and may hint at underlying coronary disease, even when ejection fraction looks normal. Image
7/
Echo also evaluates overall heart pumping ability.
Using the Simpson biplane method, we calculate left ventricular ejection fraction (LVEF).
Reduced EF in CAD patients often reflects myocardial damage from ischemia or infarction. Image
8/
But CAD doesn't only affect the left ventricle.
Right ventricular infarction can occur, especially with right coronary artery occlusion.
Echo findings may include:
🔵 RV wall motion abnormalities
🔵 Reduced TAPSE
🔵 RV dilation Calculation of fractional area change (FAC) from tracings of end-diastolic area (EDA) and end-systolic area (ESA) of the right ventricle.
Image
Dilatation and loss of respiratory diameter changes of vena cava inferior visualized by using the M-mode method from subcostal view.
9/
Another complication cardiologists watch closely is ischemic mitral regurgitation.
After MI, the ventricle remodels → papillary muscles shift → mitral leaflets fail to coapt.
The result: MR that worsens HF and prognosis.
Echo is essential to diagnose and quantify it Image
10/
Despite newer imaging technologies, echo remains indispensable in CAD.
It helps us evaluate:
- myocardial fx
- ischemia
- ventricular remodeling
- valve complications
- hemodynamics
All in real time, at the bedside.
Sometimes the most powerful tools are still the simplest.
References:


@TrackYourHeartsciencedirect.com/science/articl…

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More from @TrackYourHeart

Mar 9
Why ST Elevation Isn’t Always a STEMI.

Every clinician has felt that moment…

You see an ST elevation on #ECG and your heart rate goes up before the patient’s does. STEMI? Cath lab activation? Thrombolysis?

But here’s the reality:
Not every ST elevation means ACS
A 🧵 Image
1️⃣ Acute Coronary Occlusion (STEMI)

The classic cause. When a coronary artery is blocked, transmural myocardial ischemia develops and the ST segment elevates.

Time = muscle.
Reperfusion therapy (PCI or thrombolysis) has the greatest benefit when done early. Image
2️⃣ Transient Ischemia Without Infarction
Seen in Prinzmetal’s angina or milder forms of Takotsubo cardiomyopathy.

The key feature here?
✅ ST elevation is temporary, reversible, and not associated with necrosis if treated promptly.

After the spasm resolves, the ECG normalizes. Image
Read 14 tweets
Mar 8
Palpitations, syncope, unexplained arrhythmias: which cardiac monitor should you choose?
A short guide to the most commonly used ambulatory ECG monitoring devices and when to use them. 🧵 Image
1/ Holter Monitor
A portable ECG device that records continuously for 24–72 hours (up to ~2 weeks in newer models).
Patients can mark symptoms using an event button or diary to correlate symptoms with rhythm.
Best for frequent symptoms expected to occur within a few days. Image
2/ Event Monitor
Records ECG only when the pt activates it during Sx and sends the recording to a monitoring center via telephone.
Useful when Sx occur intermittently within 2–6 weeks.
Limitation: not ideal for sudden syncope, since the pts may not be able to activate the device. Image
Read 8 tweets
Mar 7
🧵 Why can oxygen worsen respiratory failure in COPD?
Many clinicians still fear giving oxygen to COPD patients.
The reason they’re taught?
"Loss of hypoxic drive"
But this is mostly a myth.
Here’s what really causes oxygen-induced hypercapnia 👇 Image
Oxygen does NOT usually cause dangerous hypercapnia by stopping breathing.
Studies show:
- Ventilatory drive remains high
- Minute ventilation recovers quickly
- CO₂ continues to rise anyway
So what’s the real mechanism? Effect of minute ventilation during oxygen-induced hypercapnia. During 15 minutes of high oxygen administration, an initial decrease in minute ventilation, which recovers substantially, is seen in patients with acute exacerbation of chronic obstructive pulmonary disease. However, the oxygen-induced hypercapnia does not recover. CO2, carbon dioxide; VE, minute ventilation. Based on data of Aubier and colleagues .
1️⃣ Worsened ventilation–perfusion (V/Q) mismatch, the BIGGEST factor
High FiO₂ reverses hypoxic pulmonary vasoconstriction, sending blood to poorly ventilated alveoli → ↑ dead space → ↑ PaCO₂
This explains most of the CO₂ rise Image
Read 9 tweets
Mar 6
High blood pressure is often called the "silent killer."
Yet it remains the most common modifiable risk factor for heart disease and stroke worldwide.
Here are the key takeaways from the 2025 ACC/AHA Hypertension Guideline every clinician should know. 🧵 Image
1/
High blood pressure remains the most common modifiable risk factor for cardiovascular disease.
It contributes to coronary artery disease, HF, stroke, atrial fibrillation, dementia, CKD and premature death.

The general treatment goal for adults: <130/80 mm Hg.
2/
Early detection matters.
Clinicians, health systems, and community leaders should work together to screen all adults regularly and implement guideline-based prevention and treatment strategies to improve blood pressure control.
Read 12 tweets
Mar 5
Interpreting an #ECG can seem overwhelming at first, but with a structured approach, it becomes far more manageable.

In this thread, I’ll walk you through how to analyze an ECG like a professional, step by step.

Let’s begin.🧵 Image
Step 0: Initial Checks
1. Paper Speed
The standard ECG paper speed is 25 mm/s, meaning:
◾1 small square = 0.04 s
◾1 large square = 0.20 s (5 small squares)
2. Calibration
This determines the amplitude of the waves:
⏺️ 1 mV = 10 mm (i.e., 2 large squares vertically Image
Step 1: Heart Rate (HR)

If rhythm is regular:
Use the formula
Heart Rate = 300 / number of large squares between R waves

Alternatively, memorize the sequence:
300 → 150 → 100 → 75 → 60 → 50
Estimate HR by seeing where the next R wave falls in this pattern. Image
Read 15 tweets
Feb 5
🧵 Thread: Brugada-type ECG, beyond the classic Type 1 pattern
1/
Brugada syndrome is defined by dynamic ECG changes in the right precordial leads (V1–V3), not a single static pattern.
Understanding when and why these patterns appear is as important as recognizing them. Image
2/
Consensus classification describes three Brugada-type ECG patterns based on ST-segment morphology and J-point amplitude:
🟢 Type 1 (coved)
🟢 Type 2/3 (saddleback spectrum)
🟢Type S (mild coved, “suggestive”)
📌 Only Type 1 is diagnostic. Image
3/
Type 1 pattern
- Coved ST elevation ≥2 mm
- Gradual downsloping ST
- Negative or isoelectric T wave
This pattern may be spontaneous or unmasked under specific conditions Image
Read 12 tweets

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