tern Profile picture
Mar 20 24 tweets 3 min read Read on X
Don't you get it?

If lots of people in your population have lower ability to fight infection, it doesn't just mean those people are more likely to *catch* infections.

It means they are more likely to *spread* them too.

Let me explain.
This is important.
Jack has a metal lunchbox.
No ants can get into his lunchbox, so when he leaves the park, no ants fall out of his lunchbox.

Annie has a lunch bag made of wool.
Ants can climb into it, and they can also fall out easily too.
And that's what they do.
Obviously it's more complex than that. But if you don't catch something in the first place then you don't spread it.

But there's much more to it than that.
You can only spread it if you catch it.

And if there's a problem with your body's defences (and the science is now endless that explains how Covid infections damage your body's defences) then you're more likely to catch something.
If you're less able to fight the infection, then you carry the infection for longer, so you may be infectious for longer.

And covid infections make you less able to fight other infections.
And if your body is less able to keep the infection under control, it may be that the infection reproduces in greater quantities, so there's more to infect other people.

And covid infections make your body less able to keep other infections under control.
Now, we know very well now, from repeated studies, that most people are left with a *slight* reduction in ability to fight other infections after they've caught Covid.
So in that circumstance most people are *slightly more likely* to both catch and spread other infections.
But we also know that some people have a significant loss of ability to fight infection after they've caught Covid.
So among the population who are *slightly more likely* to catch and spread something, you also have people who are *much more likely* to catch and spread something, and *much more likely to be seriously ill*.
Or die.
So you get a two layered effect:
Most people being slightly more likely.
Some people being much more likely.
And the cumulative effect of those two layers is *outbreaks*.
And what have we had these last six years?

<Big Outbreaks>
It's like wildfire season:

The trees are more likely to catch.

And then when they do, they burn hotter and are more likely to spread the fire.

And they are more likely to be completely destroyed.
Fortunately people's bodies still retain a strong ability to build at least short lasting immunity to those infections that have flown round.

So in the last five years we have had massive serious outbreaks of
Strep A
Whooping Cough
Mycoplasma pneumoniae
But we've also had a load of serious smaller outbreaks on local levels.

Think of the cryptosporidia, clostridium, shigella, lambia, salmonella, E Coli, klebsiella, campylobacter, legionella, pseudomonas, and others increases.
Because everyone only needs to be slightly more likely to catch and spread stuff for a lot more people to catch and spread stuff.
And so you get the BBC trying to wrap their heads around situations like this: Image
The meningitis outbreak only defies explanation if you refuse to accept that covid infections make you more vulnerable to other infections.
And there's an extra bonus too.

People often carry meningitis bacteria around harmlessly in their nose and throat without developing the full blown illness that happens when it gets into your blood or brain.
But Covid infections can both damage the tissue of your nose and throat to allow access... but also make you more prone to *other infections that damage your nose and throat* to amplify the chance of bacteria being able to get through.
And covid infections also damage the blood brain barrier too, so there's that.
And every covid infection *adds* to the risk.

So the more covid infections people have, the more vulnerable our population will be to these outbreaks.

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More from @1goodtern

Mar 22
Five things about this study.

First, even mild Covid infection screws your immune system so you're 60% more likely to be hospitalised by EBV/mono/glandular fever for and the effect lasts ages.

Covid infection can screw up your immune system.
Second, we're talking about *hospitalisation* by EBV after the covid infection, so it's not just getting extra 'mild' bugs afterwards.
Third, the hospital data doesn't say whether the hospitalisations were *reactivations* or *new infections* of EBV.

But it's probably a bit of both.

I've been hospitalised by reactivated EBV. It was unpleasant.
Read 16 tweets
Mar 21
I've seen this gotcha quite a few times now:
"If the Kent meningitis outbreak was caused by Covid, why is it just in Kent?"
Which completely misses the point of what people mean when they say that outbreaks like this are made more likely by the damage caused by covid infections.
Wildfires aren't a perfect analogy for infection outbreaks - but they can help us understand certain aspects.

Think of a whole country made more prone to wildfires by a drought.
The whole country doesn't suddenly burst into flames.

In a drought ridden country, what happens it that you get wildfires happening locally sporadically.
Read 59 tweets
Mar 20
Enormously massively huge studies have shown that each wave of Covid infections causes damage to people's immune systems. The science is incontrovertible.

And yet you will not find a single media article about the current meningitis outbreak that mentions that.
It's really simple.
It's been established science for decades that "a low CD4 count... has been shown to be associated with an increased risk of Invasive Meningococcal Disease"
Governments base policies on this established science.
pmc.ncbi.nlm.nih.gov/articles/PMC10…Image
And Covid infection... Covid infection hammers your lymphocytes including CD4 T cells... and the rest. Image
Read 11 tweets
Mar 19
Ten things they'll be telling us about meningitis before the end of the week:
1
It's mild
2
Kids can't get it.
Read 56 tweets
Mar 19
I'm sitting at my computer with 46 tabs open with media stories about the meningitis outbreak from the last 3 days.

Following mainstream coverage, govt statements and UKHSA briefings on the meningitis outbreak has been surprisingly tiring.

Here are a few of the inconsistencies:
"Outbreak has been contained." Then within 16 hours: "It is too soon to say the outbreak is contained."
UKHSA said this looked like a "single event cluster" linked to a nightclub. Then they started saying there was likely "ongoing spread" in university halls. A contained exposure event and active transmission through accommodation networks are not the same thing, Susan.
Read 21 tweets
Mar 13
All day I've been whacking my head against this vital tweet and the press release attached to it.

It's probably one of the most important things I've read about the early progression of the pandemic, but it's very hard to express concisely the huge scandal they've exposed here.
The central difficulty with getting your head round it is that there are *two* scandals detailed here:

👉The first is that key advice by experts was ignored in 2020.

👉The second is that a huge amount of money seems to have been spent covering that up.
So you need to think about the first scandal first, before being able to fully appreciate the second one.
Read 22 tweets

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