Thread by @aestheticprimal

Shilajit is NOT a Testosterone booster, it is a mitochondrial enhancer, which is where it truly shines.

1g in morning = amazing workout + brain energy

but why?

THREAD🧵

DBPs in Shilajit (and why they're so interesting)

Most people talk about how Shilajit contains a lot of trace minerals and Fulvic acid.

But the most interesting compounds that can be found in Shilajit are the DBPs, which are also known as:
Dibenzo-alpha-pyrones

let me explain👇

Why are these DBPs so beneficial?

there are 3 big reasons

(boring science warning)

NUMBER ONE:
they're 'Quinone-like' compounds

DBPs are technically not Quinones, because they do not have the structure of a Quinone (their core structure is a fused tricyclic lactone and not a cyclic dione)

But they act like quinones in redox reactions, electron transport, and mitochondrial function due to how they cycle between three redox states (reduced, semiquinone radical, and oxidized/quinone-like forms).

Accepting electrons from Complex I and II →  then carrying those electrons to Complex III → in Complex III the electrons are donated and carried to Complex IV where the electrons are handed off to Oxygen preventing electrons to accumulate at Complex III and excess ROS to be produced

NUMBER TWO:
They work in tandem with CoQ10

CoQ10 shuttles electrons between Complex I/II & III but can be easily oxidized back from Ubiquinol (active CoQ10) back into Ubiquinon (oxidized form) under stress.

DBPs prevent the oxidation of Ubiquinol into Ubiquinon, and keep CoQ10 in its reduced form, protecting it from oxidative stress.

What does this mean?
Ubiquinol stays active for a longer time duration in the ETC (electron transport chain) causing less electron leakage and increased ATP production
↓
Ubiquinol is kept in the reduced form and its ability to neutralize free radicals is extended because of how Ubiquinol acts as antioxidant
↓
Mitochondrial membrane potential is now better preserved
↓
Energy production stays stable and efficient under stress, heavy exercise or even prolonged period of focus and attention
↓
Can handle more exercise, more work and even more emotional stress

(more on how Shilajit/DBPs enhance brain energy through improved mitochondrial function of the PFC later in this thread)

NUMBER THREE:
Mitophagy benefits of DBPs

Mitophagy is the process where your cells detect/recycle damaged/dysfunctional mitochondria through autophagy which prevents excessive ROS/oxidative stress and ensures that inefficient mitochondria are cleared away, keeping energy production efficient.

This helps to prevent fast aging, low energy and diseases.

So how does Shialjit enhance mitophagy through DBPs?

One of the primary DBPs in Shilajit is:
‘3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one’

this DBP is chemically similar to Urolithin A

It stabilizes PINK1 on damaged mitochondria, which then helps to recruit ‘Parkin” which then makes the mitochondria a visible target for mitophagy by attaching ubiquitin chains to the many proteins that sit on the outer membrane of the mitochondria.

Another great benefit of Shilajit are the cognitive benefits.

It keeps your Prefrontal Cortex running after prolonged exertion and even stress, preventing your brain from 'fatiguing essentially'

This makes it a great tool to LOCK IN for longer time durations.

The reason?

DBPs in Shilajit enhance mitochondrial function in the brain, and the Fulvic acid helps the DBPs to actually penetrate into the cell as well as improving its intestinal absorption

Shilajit then helps to keep the mitochondrial membrane potential up when energy demands rise under stress.

The brain will basically not suffer from lower energy.

This then also modulates the HPA axis, preventing the release of glucocorticoids like Cortisol

Cortisol basically is a catabolic hormone that signals to the body to break down fat, muscle and other tissues to mobilize more energy.

Stable mitochondrial function prevents the body from having to mobilize energy through Cortisol

since energy production is still running stable.

The real problems with Shilajit are the following:

→ people expect Testosterone as the main benefit and not improved mitochondrial function, where it ACTUALLY shines

→ They don't use purified Shilajit in resinous form that has been PURIFIED, which leads to mycotoxins being present

→ Low-quality Shilajit is used that has high levels of heavy metals

These things are important, and I have tried my best to offer source good quality 'Jit from Kazakhstan, with test results attached down below.

If you want to give it a try

Obtain some here and use code 'SUMMERSALE15' which will give you 15% off (code expires Tuesday 16:00 CEST)

Shilajit: aesthetic-alimentum.com/products/naaml…

thanks for reading!