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Agustin Ibañez Profile picture
Agustin Ibañez
@AgustinMIbanez
Scientific Director, Latin American Brain Health Institute @BrainlatUAI-@UAI_CL; Prof. at @GBHI_Fellows-@tcddublin, Researcher @CNCUdeSA; Atlantic Fellow UCSF
Jul 14 • 6 tweets • 3 min read
From political unrest to toxic air and social stress, the world around us can accelerate the aging process. Out today in @NatureMedicine: our work on how the environment seeps into health and makes us older
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@EricTopol @jayvanbavel @GBHI_Fellows @BrainlatUAI @Nature @NaturePortfolio @NTFabianodoi.org/10.1038/s41591…Image The Biobehavioral Age Gap (BBAG) in 160,000+ people (40 countries) compares the real age to an estimated age from protective (education, functionality, cognition, wellbeing, physical activity), & risk factors (heart disease, diabetes, hearing/visual deficits, weight)
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Nov 14, 2022 • 5 tweets • 5 min read
High-order dynamics in brain networks & dementia are not well-captured by connectivity. We developed a new framework of high-order interactions (3-to-N plets) with information theory + greedy algorithm in #fMRI - #EEG across #AD & #FTD Paper doi.org/10.1016/j.nbd.… & 🧵👇1/5 Image High-order functional connectivity (HOFC) at 3-15 plets yielded networks with large effect sizes for both modalities (fMRI and filtered EEG) and comparison (CN vs. AD, CN vs. FTD). Results included decorrelated networks for fMRI and EEG but also hyperconnectivity. 2/5 Image