Director, Latin American Brain Health Institute @BrainlatUAI at @UAI; Ass. Res. Prof. at @tcddublin, Researcher @CNCUdeSA; Senior Atlantic Fellow @GBHI_Fellows
Nov 14, 2022 • 5 tweets • 5 min read
High-order dynamics in brain networks & dementia are not well-captured by connectivity. We developed a new framework of high-order interactions (3-to-N plets) with information theory + greedy algorithm in #fMRI - #EEG across #AD & #FTD Paper doi.org/10.1016/j.nbd.… & 🧵👇1/5
High-order functional connectivity (HOFC) at 3-15 plets yielded networks with large effect sizes for both modalities (fMRI and filtered EEG) and comparison (CN vs. AD, CN vs. FTD). Results included decorrelated networks for fMRI and EEG but also hyperconnectivity. 2/5