AlexanderSHatoum Profile picture
Psychiatric, statistical, and imaging geneticist. Interested in translational methods and modeling addiction comorbidity. WUSM Psych. Tweets are my own. He/His
Jan 28, 2021 9 tweets 5 min read
Preprint alert! TL;DR We find that a common genetic mechanism underlies Substance Use Disorder behaviors, and remains when controlling for genetics of substance use. Suggesting an #addictions genetic mechanism, what we call the a(g)-Factor, a thread! 1/8 medrxiv.org/content/10.110… Polysubstance use or substitution behaviors are the norm among cases. With more lifetime SUDs comorbidity we often see more severe presentations of Substance Use Disorders (SUDs). Our current nosologies are defined by the drug, but there are efforts to find deeper mechanisms. 2/8