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GI fellow @GMC Hyderabad. MD internal medicine @SPMC Bikaner.MBBS @SDUMC Kolar .โฌ†๏ธ https://t.co/OOCPCtUhwi Farming . TTplayer. Travel ๐Ÿงญ,Explore ๐Ÿ‡ฎ๐Ÿ‡ณ.
Sep 17 โ€ข 11 tweets โ€ข 4 min read
โœจ APASL 2025 AVB Guidelines vs 2011 โœจ

1๏ธโƒฃ Refined definitions & risk stratification โ†’ โ€œHome-to-doorโ€ ๐Ÿ โžก๏ธ๐Ÿฅ, APASL Bleed Severity Score, HVPG, AI ๐Ÿง 
2๏ธโƒฃ Expanded rescue therapies โ†’ SEMS, early-TIPS, EUS-guided glue/thrombin, BRTO/CARTO/PARTO ๐Ÿ’‰
3๏ธโƒฃ Personalized pharmacology โ†’ region-specific antibiotics ๐Ÿ’Š, tailored vasoactives
4๏ธโƒฃ Standardized endoscopy โ†’ EVL = gold standard ๐Ÿ‘‘ + anesthesia/risk guidance
5๏ธโƒฃ Greater clinical focus โ†’ practical, Asia-Pacific-specific ๐ŸŒ

๐Ÿ‘‰ More precise, dynamic & practice-ready for better #AVB outcomes โœ…

#Hepatology #GI #Liver #Cirrhosis #VaricealBleed #APASL2025 #Guidelines

link.springer.com/article/10.100โ€ฆImage ๐Ÿ“˜ New APASL Definitions (2025)

๐Ÿ”ด Acute Variceal Bleeding (AVB):
โžก๏ธ Hematemesis within last 48h ๐Ÿฉธ
โžก๏ธ Ongoing melena (last stool โ‰ค24h) in suspected/known PHT

๐Ÿ”„ Re-bleeding (post AVB control):
โฐ Very early: 48โ€“120h
๐Ÿ—“ Early: 120h โ€“ 42 days
๐Ÿ“… Late: >42 days Image