1- Dysautonomia Trifecta

Dysautonomia Trifecta— an informal, colloquial term sometimes used in patient communities and among certain clinicians to describe the cluster of overlapping dysautonomic syndromes that tend to co-occur in certain individuals. 2- What “Dysautonomia” Means

Dysautonomia refers to dysfunction of the autonomic nervous system (ANS) — the system controlling involuntary body functions like heart rate, blood pressure, digestion, temperature regulation, and pupil

1- OSPA?

Let's go deep into how OspA (Outer Surface Protein A) potentially induces autoimmunity through molecular mimicry and immune system dysregulation.

This is a case study in how a superficially clever v@ccine design collided with the real complexity of the immune system. 2- 1. The Nature of OspA

OspA is a lipoprotein anchored in Borrelia burgdorferi’s outer membrane.
Unlike most bacterial proteins, it’s highly immunogenic — meaning it’s efficient at provoking a strong immune response — but unfortunately, it resembles certain human cell-surface proteins too closely.

The basic aim of the Lyme vaccine was to make the body produce anti-OspA antibodies that would circulate in the blood and, when a tick fed, kill Borrelia in the tick’s midgut.

The flaw: those anti-OspA antibodies do not stop at the tick — they can also bind to self-tissues with homologous peptide sequences.

The National CFIDS Foundation's radiation model

The National CFIDS Foundation proposed a model suggesting a link between low-dose radiation exposure and Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME/CFS).

This model hypothesizes that chronic exposure to low-level radiation, such as from internal radionuclides, can cause gradual cellular damage, leading to symptoms by disrupting cell function. Key findings from their research include identifying hydroperoxides (cardiolipin and phosphatidylserine) resulting from this cellular injury, which damage mitochondria and red blood cells. 

The National CFIDS Foundation's radiation model

Mechanism: The foundation's model proposes that constant, low-level radiation exposure from sources like ingested or inhaled radionuclides leads to accumulated cellular injury over time.

Cellular Damage: This process creates specific hydroperoxides, such as cardiolipin hydroperoxides and phosphatidylserine hydroperoxides.

Functional Impairment: These hydroperoxides are thought to act as cellular toxicants that impair normal cell function.

Specific Impact:

Mitochondrial Dysfunction: Cardiolipin hydroperoxides disrupt the proper function of mitochondria, the energy-producing centers in cells, leading to energy deficits.

Red Blood Cell Impairment: Phosphatidylserine hydroperoxides alter red blood cell function and affect oxygenation of tissues.

Combined Effect: The combination of these two effects is believed to create a "perfect storm" of cellular dysfunction that contributes to the symptoms of CFS.

Evidence and Support:

Reports from Chernobyl and other sources have previously associated radiation exposure with CFIDS.

The foundation also identified chromosomal damage in a patient cohort that had been screened for urinary radionuclides. 

ncf-net.org/latest-news/na… 2-National CFIDS Foundation Creates New Disease Model for its Radiation-Exposed Patient Cohort

January 30th, 2024

by National CFIDS Foundation © 2024

The National CFIDS Foundation (NCF) identified radiation exposure and subsequent chromosome damage in its own patient cohort a decade ago. In more recent years, scientists, working with the NCF, have made noteworthy discoveries that have assisted in the generation of this model, the first of its kind to be applied to Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS) also known as Chronic Fatigue Syndrome (CFS) as well as Myalgic Encephalomyelitis (ME).

According to Gail Kansky, NCF President, "This is the beginning of a roadmap thatconnects radiation exposure to clinical disease markers that are present in patients."

Though we have our own work cut out for us, we are excited to be formally published. Without such a roadmap, meaningful treatments may just be a shot-in-the-dark and we would very much like to avoid that due to the complexity of the disease," stated Alan Cocchetto, NCF Medical Director.

This brings the NCF and its patient cohort one step closer to appropriate testing and ultimately towards greater understanding of the disease process that we hope will yield much needed targeted therapies.

To read the paper in the International Journal of Molecular Sciences, titled "A Proposed New Model to Explain the Role of Low Dose Non-DNA Targeted Radiation Exposure in Chronic Fatigue and Immune Dysfunction Syndrome"

ncf-net.org/latest-news/na…

1- Myalgic Encephalomyelitis

Emotional control (or rather, loss of emotional control) in Myalgic Encephalomyelitis (ME) is a recognized and distressing symptom — but it’s not a sign of a psychological disorder. It reflects neurological injury and Dysregulation caused by the disease.
#NightingaleContinuum
pubmed.ncbi.nlm.nih.gov/21777306/ 2-Myalgic Encephalomyelitis

Neurological basis
ME affects the central nervous system (CNS), including areas involved in emotion regulation — such as the limbic system, brainstem, and prefrontal cortex. SPECT and PET scans in ME often show hypoperfusion (reduced blood flow) and inflammation in these same regions.

This means the brain has less capacity to filter, modulate, or dampen emotional signals, so:

* Reactions can be intense and sudden (e.g., tears, irritability, frustration).
* It’s not mood instability in a psychiatric sense; it’s neurological exhaustion.

1- 1993: Living Hell
Crime of Deception: HGRV Epidemic the CDC calls CFS (Part 1 of 6)
2- 1993: Living Hell
Crime of Deception: HGRV Epidemic the CDC calls CFS
(part 2 of 6)

1-Akkermansia Muciniphila 101: Everything You Need to Know About This Important Gut Bacteria

"Akkermansia muciniphila is a novel probiotic strain discovered in 2004 when scientists at Wageningen University of the Netherlands were searching for a new mucin‐degrading microbe. Research has rapidly expanded in the last several years, leading to the identification of how this keystone bacterial strain functions in the gut to impact health throughout the body."

rupahealth.com/post/akkermans… 2-Here's How Akkermansia Works 

The lining of the intestines is made up of epithelial cells, i.e., the cells that cover the surfaces of bodily organs. These epithelial cells are covered in a slimy mucus layer rich in protein called mucin. Akkermansia muciniphila was actually named after the microbial ecologist Antoon DL Akkermans, and muciniphila translates to "preferring mucin." This is because the Akkermansia strain uses mucin for energy. The more mucin Akkermansia uses, the more it encourages the epithelial cells to make additional mucin. This additional "mucin making" may help support the intestinal wall, which is important for gut health and overall well-being.

1-Nexavir (Formerly known as Kutapressin)
Uses:
EBV
ME and CFS
HHV6
Shingles
Rosacea
HIV/AIDS
Chemo Brain
Hepatitis C

nexco-pharma.com/research-and-u… 2- Nexavir (Formerly known as Kutapressin
COVID Long Haulers:
nexco-pharma.com/covid-longhaul…

1-Myalgic Encephalomyelitis

Body weakness in Myalgic Encephalomyelitis (ME) is one of the core and most disabling symptoms. It’s not ordinary fatigue or deconditioning—it’s a neuromuscular weakness that reflects dysfunction in the central nervous system (CNS), autonomic nervous system, and cellular energy metabolism

Nature of Weakness

* Neuromuscular, not psychological: The weakness in ME is caused by impaired nerve and muscle signaling, not by lack of effort or mood.

* Fluctuating: It can worsen after minimal exertion (mental, emotional, or physical).

* Post-exertional: Even mild activity (talking, standing, or showering) can lead to profound muscle weakness hours or days later (Post-Exertional Neuroimmune Exhaustion, PENE).

* Disproportionate to effort: Patients often describe feeling as though their limbs are made of “lead” or “cement.”

Physiological Findings
*Reduced muscle oxygenation: Studies using near-infrared spectroscopy and exercise testing show that muscles in ME patients extract and utilize oxygen poorly.

*Mitochondrial dysfunction: Muscle biopsies and metabolic studies reveal impaired ATP (energy) production and abnormal lactate accumulation after exertion.

*Autonomic nervous system dysfunction: Orthostatic intolerance and poor blood flow regulation can cause inadequate delivery of blood and oxygen to muscles, worsening weakness when standing.

*Abnormal muscle excitability: Electromyography (EMG) and single-fiber studies show delayed muscle recovery and impaired nerve signal transmission.

*Immune activation: Cytokines such as IL-6 and TNF-α, found elevated in some studies, can contribute to muscle fatigue and pain. 2- Clinical Presentation

* Weakness that increases with activity rather than improves with exercise.

* Delayed recovery — days or even weeks after overexertion.

* Fine motor weakness — difficulty gripping objects, writing, or typing.

* Proximal muscle weakness — especially in thighs, shoulders, and neck.

* Speech and swallowing difficulties in severe cases due to cranial nerve or muscle involvement.

* In bedbound patients: even lifting a limb or turning in bed can be impossible.

@SabinehazanMD @missyTHX1138 @DrAngela4Health @EMUSBACKAGAIN @Jikkyleaks @Fynnderella1 @KevinMcCairnPhD @53v3n0fn1n3 @HouseLyndseyRN @28103Annie @Nuni_Sas_Yu @DrNoMask @drcraigwax @BrocaSpeaks @karrichapus @canceledmouse @DrTessaT @DrWoofAus @CharlesRixey @docbiss I pay cash for the doctor who treats the Dysautonomia - OH and POTS for. I get good service!
POTS was recognized in 1943- docs still have no clue!
I have shown a number of COVID jab injured people how to show their doctor that they have POTS-their docs should pay me a %! @SabinehazanMD @missyTHX1138 @DrAngela4Health @EMUSBACKAGAIN @Jikkyleaks @Fynnderella1 @KevinMcCairnPhD @53v3n0fn1n3 @HouseLyndseyRN @28103Annie @Nuni_Sas_Yu @DrNoMask @drcraigwax @BrocaSpeaks @karrichapus @canceledmouse @DrTessaT @DrWoofAus @CharlesRixey @docbiss If you can't pay the cash, stay away from the docs in groups, you want the single practice docs, they are still out there.
I have always kept 2 GP's on the table like that for years- You need to "work the system" like that with these chronic issues.

1-Astroturf and Manipulation of Media Messages | Sharyl Attkinson

2- Consider this fictitious example that’s inspired by real life: say you’re watching the news, and you see a story about a new study on the cholesterol-lowering drug called cholextra. The study says cholextra is so effective that doctors should consider prescribing it to adults and even children who don’t yet have high cholesterol.

Is it too good to be true? You’re smart, you decide to do some of your own research. You do a Google search, you consult social media, Facebook, and Twitter. You look at Wikipedia, WebMD, a non-profit website, and you read the original study in a peer-reviewed published medical journal. It all confirms how effective cholextra is. You do run across a few negative comments and a potential link to cancer, but you dismiss that, because medical experts call the cancer link a myth and say that those who think there is a link, they are quacks, cranks, and nuts.

A Tragic Case of Vaccine Induced Neuroimmune Disease 1/3

"The Blood Letters" by Joan Luther Irvine
#ACTUP4ME
#pwme
#MEcfs
#MyalgicE

https://x.com/AnneSpaceCoast/status/705182869912555520

web.archive.org/web/2009110800…