These are astonishing results in weight loss. 24.% weight loss at 48 weeks. Average loss of 58 pounds. Blows out of the water everything else we've seen so far.

endpts.com/lillys-retatru… For context: Every other weight loss drug we've seen is around 15%. Which was already awesome. This is 10pp higher than that.

The debate has been around "will the new pill versions wipe out the injections" and this just reset the conversation.

Holy smokes.
bloomberg.com/news/articles/… Co press release here (fuller data in Nov.)

investors.biogen.com/news-releases/…

ICMYI: Pandemic Prevention Institute CEO @RickABright will leave the institute he helped get off the ground after leaving the US gov. (@PPI_Insights)

https://twitter.com/ArmstrongDrew/status/1574579016182292480

Bright joined the institute to lead as CEO in March 2021 -- still hot in the middle of the pandemic, meaning his tenure spanned about 18mos.

The @RockefellerFdn funded it w/ $150M, per Oct. 2021 release:
rockefellerfoundation.org/news/the-rocke…

More than two years into the pandemic, how we measure Covid, how we think about risk + consequence, and how we react to the virus has changed.

The way we measure Covid-19 needs to change too.

bloomberg.com/news/articles/… Over the last several months, I spoke to dozens of disease modelers, epidemiologists and public health officials about what's changed, what they don't know, what they wish they knew, and how they think about what we've been through.
bloomberg.com/news/articles/…

Time to finally implement the "It costs $1 to send 1 tweet" business plan. Reading tweets can be free.

Reporting in Kentucky hospitals, I saw a lot of covid patients. What are they like?

One man was in a high-flow oxygen mask. He was lying in bed, making tiny, fast bites at the air, gasping.

He looked like he was suffocating, like a dying fish washed up on the beach. I saw other patients on ventilators. They're pale and sedated.

They look dead, until the ventilator pushes air into their lungs and their chest heaves upward. None of the looks natural, and it's very, very upsetting to watch.

“The next person who shows up, we’re just going to have to let them pass away. We have nothing left.”

“Five people died that day and that’s what saved us."

This is what it looks like when a state's hospital network gets overwhelmed with Covid patients.

bloomberg.com/graphics/2021-… 🏥A few months ago, I started a project with @DavidIngold. I wanted to think about how Covid affects health-care SYSTEMS, not just individual hospitals.

What happens to a network of hospitals across a state or region, in places (like a lot of the U.S.) with varying vax rates?

Pfizer going with the very dignified chamber orchestra winds/strings hold music as we get started here. I might have gone a little more Wagnerian given the absolutely massive revenue number, but nobody asked me. I mean, at 130% revenue growth, you can add a percussion section in there.

💉VACCINE TREND UPDATE 📈
In some of the places hit hardest by the new Covid wave (including many vaccine-lagging places), the surge in cases has been followed up a surge in vaccinations.

Check these maps. Blue is where vaccinations are highest. Yellow is where cases are. In Louisiana, Missouri and Arkansas in particular, there's been a rebound in vaccinations to levels not seen since the spring.

They're reporting the highest rate of new vaccinations since mid-April in Arkansas + Louisiana, and since late May in Missouri
bloomberg.com/news/articles/…

CDC presser on masking: CDC saying delta behaves differently than prior strains of the virus, and that some people who get infected post-vacc can be spreaders. Mask guidance update here: bloomberg.com/news/articles/…

What's causing the blood clots? FDA's Peter Marks says this is just a theory, but that it could be an immune response that occurs very rarely after vaccination, causing activation of blood platelets. Presser available live here:

👀The FDA and CDC are calling for a pause in the use of J&J’s vaccine after a series of blood clots in six women.

Statement: So far, about 6.86 million doses of J&J’s vaccine have been used in the U.S., so that’s a known rate of less than 1 in 1,000,000.

We are now tracking U.S. vaccine availability by week, and comparing it with manufacturer projections:

Full graphic here: bloomberg.com/graphics/covid… We know there's been a lot of interest -- especially recently! -- in "how many shots are out there." Now you can see that, and see what's coming:

💉VACCINE DATA UPDATE (March 27)💉

📊3.5M doses today; 7-day avg=2.68M/day
🇺🇸US: 140M doses total

☝️Looking like another U.S. inflection point may be brewing, with the 7-day tilting up two tenths after being stuck at 2.5M

Full data/graphic: bloomberg.com/graphics/covid… This is a one-day record -- the second in a row. (The 4.5M day a big ago is an artifact of CDC's data reporting, which we'll correct if we can but.... it's a bit complicated.)

💉VACCINE DATA UPDATE (March 26)💉

⭐️A record day of vaccinations reported in the U.S., which pushes up our U.S. 7-day average to 2.62M/day.

📊3.4M doses today; 7-day avg=2.62M/day
🇺🇸US: 137M doses total

Full graphic/data: bloomberg.com/graphics/covid… 🧵2/ If past trends hold, we could be in for some very big numbers this weekend. (Saturdays and Sundays have been among our biggest days, typically.)

Here's why the U.S. reported an absolutely massive 4.6M doses on Saturday (more than 50% higher than any prior report).

The boring answer: It's a one-time methodological bump from a later-than-usual CDC data pull that sucked in more data than usual.

bloomberg.com/news/live-blog… This means (assuming CDC reverts back to it's normal data pull time) that Sunday's number will probably be smaller than it would be otherwise.

Here's my earlier thread taking some guesses at what's going on.

https://twitter.com/ArmstrongDrew/status/1370879433746305025

💉VACCINE DATA UPDATE (March 13)💉

🚨Record day of reported vaccinations, with 4.6M. 50% higher than past 2.9M record. Looking into why (data dump/lag, +capacity, etc.)

📊4.6M doses today; 7-day avg=2.54M/day
🇺🇸US: 106M doses total

Full graphic/data: bloomberg.com/graphics/covid… ⚠️This is a huge number that's 50% bigger than we've ever seen. it's possible there's some sort of data/methodological reason for this. We are investigating and will post a blog/more tweets if we find out something more.

In the meantime, <sportscenter voice> THAT'S A BIG ONE

💉VACCINE DATA UPDATE (March 12)💉

⭐️The U.S. has crossed the 100M-dose mark, less than 3 months into the vaccination campaign

📊2.9M doses today; 7-day avg=2.3M/day
🇺🇸US: 101M doses total
👨‍👩‍👧‍👦66M people w/ at least 1 dose

Full data: bloomberg.com/graphics/covid… (Deleted prior tweet w/ the XXXX templated material)

💉VACCINE DATA UPDATE (March 11)💉

📊2.5M doses today; 7-day avg=2.23M/day
🇺🇸US: 98.2M doses total

⚠️Notes and news in the🧵below!

Full data + all the tables: bloomberg.com/graphics/covid… ⚠️Data note: We made a chance to our NYC methodology that brings it in line with the rest of the U.S. The % of people vaccinated now reflects residents, not place of vaccination. The resulted in a change to our NYC %s.

💉VACCINE DATA UPDATE (March 6)💉

⭐️One-day record, almost 3M doses reported in the U.S. Mass vaccination sites like FEMA-run centers + stadiums may be boosting numbers.

📊2.9M doses today; 7-day avg=2.16M/day
🇺🇸US: 87.9M doses total

bloomberg.com/graphics/covid… We'll be adding more granular data on J&J doses as we get it. We are hoping that will be on Monday.

💉VACCINE DATA UPDATE (March 3)💉

⭐️Our U.S. 7-day average is now 2.01M doses/day, the first time above 2M. This appears to be driven by a combo of winter-storm make-up doses + increasing supply.

📊1.91M doses today; 7-day 2.01M
🇺🇸US: 80.5M doses total

bloomberg.com/graphics/covid… If there's a significant pull-back after the storm make-up bump, this could slip back down. But between J&J doses going into arms this week + rising shipments of about 15M doses/week, that seems unlikely/short-lived.

2M+ averages may be the new normal.

bloomberg.com/graphics/covid…