Brady Holmer Profile picture
Endurance athlete. Science writer: https://t.co/kCQ0pN3X3k
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Jan 6 12 tweets 4 min read
High-intensity interval training for plaque reduction 🫀

Is HIIT safe and effective for people with heart disease?

🧵 Image Exercise is a wonder drug for cardiovascular disease (CVD) prevention and reversal.

One of the biggest risk factors for CVD development is the buildup of plaque in the coronary arteries (the arteries surrounding the heart that provide it with its own blood supply). Image
Dec 23, 2023 14 tweets 6 min read
The best time of day to exercise for health ⏰

Should you workout in the morning or the afternoon to maximize the metabolic benefits?

A 🧵 Image Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. Image
Dec 10, 2023 15 tweets 5 min read
Resistance exercise for cardiovascular health 🫀

The AHA just dropped a new Scientific Statement on the benefits of strength training.

You're going to want to bookmark this.

🧵
Image Epidemiological evidence 🌎

Adults who participate in RT have nearly a 15-17% lower risk for all-cause and CVD mortality vs. adults who report no RT.

The maximum risk reduction occurs at 30-60 minutes/week.

Despite this, only 28% of US adults participants in RT 2 days/week. Image
Dec 3, 2023 21 tweets 6 min read
Endurance exercise and atherosclerosis

Is working out too hard detrimental to heart health?

🧵
Image There’s no better way to improve your chances of aging gracefully and reduce your risk of major noncommunicable diseases than to get adequate levels of physical activity.
Nov 25, 2023 11 tweets 6 min read
Exercise is great for blood glucose control.

Is there a “best” time to exercise to obtain the most benefit?

A 🧵 Image Blood glucose and insulin sensitivity exhibit a diurnal rhythm — glucose tolerance is better in the morning compared to the afternoon and the evening.

Glucose levels are lowest around the midpoint of our sleep. In people with impaired glucose tolerance or type 2 diabetes, the nadir in nighttime glucose is followed by a rise in glucose between 3 and 9 a.m.; this is referred to as the dawn phenomenon and occurs due to the body increasing its glucose production (referred to as endogenous glucose production).
Image
Nov 9, 2023 15 tweets 5 min read
Time-restricted eating vs. calorie counting for weight loss.

Does fasting have unique benefits? Or is it all about "calories in, calories out"?

Check the link in my bio for an in-depth post.

Keep reading for a🧵
Image Fasting has several well-regarded benefits, and though many of them have only been studied in animal models to date, evolutionarily conserved processes that we share with our non-human relatives suggest that these benefits may also apply to us. Image
Nov 4, 2023 15 tweets 6 min read
Strength training vs. endurance training for healthy aging

As we get older, muscle fiber type changes, strength declines, and neuromuscular atrophy occurs.

Are lifelong athletes protected? And what's the best type of exercise to counteract aging?

A thread 🧵
Image Aging is typically accompanied by declines in maximal strength, force-generating capacity, and muscle mass.

This loss of size and strength occurs primarily in type II (“fast-twitch”) muscle fibers, resulting in an increase in the proportion of type I (“slow-twitch”) fibers. Image
Oct 29, 2023 17 tweets 5 min read
Caffeine, genes and exercise performance. ☕️

Caffeine is one of the most well-studied ergogenic aids ever - and also one of the most (legal) effective ones.

Let's talk about how caffeine improves performance and the role of genes.

Thread 🧵
Image Exercise physiologist Dr. David Costill made significant contributions to the study of caffeine and exercise performance. His research played a pivotal role in understanding the effects of caffeine during exercise.
Oct 28, 2023 12 tweets 5 min read
Nose breathing for heart health. 🫀

There are claims that nasal-only breathing is superior to mouth breathing.

How does their physiology differ? And does nose breathing really produce beneficial effects on the body?

Thread. 🧵
Image Nasal breathing warms, humidifies, and filters air; it also leads to greater production of nitric oxide (NO) in our airways, enhancing vasodilation.

In addition, when we breathe through our nose, we use our diaphragm, lowering the metabolic cost of breathing. Image
Jun 15, 2023 17 tweets 5 min read
🧵

If you’re trying to improve your aerobic capacity, what’s the best way to do it?

High intensity intervals? Lactate threshold runs? Long slow endurance training?

Here are the top protocols to optimize VO2 max 👇🏼 Aerobic base building (low- to moderate-intensity training) is an important aspect of all training programs. ⛰️

But if you’re interested in increasing cardiorespiratory fitness (VO2 max), there seems to be a clear winner in terms of which intensity is best.
Feb 1, 2023 6 tweets 2 min read
If you’re trying to practice nasal breathing during endurance/cardio or a strength session, let me introduce you to a tactic I’ve tried once or twice.

It sounds crazy (and intense), buts it’s literally zero cost and incredibly effective.

The “mouthful of water run.” This tactic was apparently practiced by the Apache tribes—who were well-known for their stamina and endurance ability.

Ala the Tarahumara tribes profiled in the book “Born to Run”.
Mar 23, 2022 6 tweets 3 min read
What is the "sweet spot" of aerobic exercise to improve longevity?

In the Copenhagen Heart Study (academic.oup.com/aje/article/17…) male and female joggers lived, on average, 6 years LONGER than non-runners.

But which levels of exercise provided the most benefit? Those running between 1-2.5 hours per week seemed to gain the greatest survival advantage vs. non-runners.

Running >2 hours per week actually erased this survival advantage -- more exercise provided no survival advantage vs. the non-runners.
Mar 1, 2022 11 tweets 3 min read
Yesterday, @foundmyfitness tweeted a study showing a 28% increase in VO2 max and an 18% increase in grip strength after 60 days of Vitamin D supplementation.

Sounds too good to be true, right?

Maybe it is. Let's discuss (thread) 👇
Study: Association of Vitamin D Supplementation in Cardiorespiratory Fitness and Muscle Strength in Adult Twins: A Randomized Controlled Trial journals.humankinetics.com/view/journals/…
Nov 26, 2019 6 tweets 1 min read
Yesterday, I “finished” my third round of physical therapy in the past 2 years.

t’s been a “miserable” 2 years of clawing my way back to running, each time to only get sidelined another injury.

But I’ve learned a few things (thread) 1. Running isn’t everything

It’s a lot of things to me, and always will be. Running is pure, meditative, and honestly one of the largest sources of joy in my life.

But can I live without it? Yes. I’ve had to...
Aug 10, 2018 11 tweets 3 min read
Why we got fat - a nice vox article with charts, to help us see that there is no ONE explanation for the epidemics of diabetes/obesity

vox.com/2016/8/31/1236… #1 - We eat out - a lot (TOO MUCH)

2015 - Americans spent more money eating away from home than they did on groceries. People typically consume 20-40% more calories in restaurants vs. at home