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Banaszynski Lab Profile picture
Banaszynski Lab
@BanaszynskiLab
Jun 3, 2019 • 16 tweets • 5 min read
The first paper from my lab was published last week in Nature Genetics @NatureGenet. The main finding is that phosphorylation on a serine that is unique to H3.3 promotes p300 activity and enhancer acetylation. nature.com/articles/s4158… This work started from an observation that H3.3 KO ESCs generally have less H3K27ac than wild-type ESCs, both globally and at enhancers.