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BowTiedBiotech 🧪🔬🧬 Profile picture
BowTiedBiotech 🧪🔬🧬
@BowTiedBiotech
Daily Biotech Updates: Public & Private Market Updates, Company Building, Financing, Exit Strategies, & Emerging Science Trends | Current: Janitor at Biotech VC
Feb 12 • 11 tweets • 4 min read
1/ THREAD: Where do mRNA vaccines go after injection?

Lipid nanoparticles (LNPs) are the workhorses of mRNA vaccines, but how do they move through the body?

New PET-CT imaging in rhesus macaques gives us answers. 🧵👇 Image 2/ Tracking LNPs in real time 📡

Researchers used radiolabeled LNPs to follow vaccine movement in living primates.

PET-CT imaging at 0, 4, and 24 hours showed LNPs don’t just stay at the injection site—they move fast. Image
Dec 2, 2023 • 12 tweets • 5 min read
1/ 🧠💻AI in Biopharma
Case Study: Roche

We will get more into this in the coming weeks in a Sunday newsletter. Sunday's are where we discuss topics related to emerging biopharma strategy.

But follow this thread for some super cool real life use cases from Roche 🧵👇
Image 2/ This use case caught our eye- using AI to develop clinical biomarkers for development.

That is an excellent idea! Have not seen much of this in action.

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Apr 2, 2023 • 10 tweets • 5 min read
1/ The future of #CANCER THERAPEUTICS is looking brighter than ever with innovative treatments like CAR-T, which involves engineering a patient's immune cells to target and destroy cancer.

A thread highlighting the emerging therapeutic platforms we are most excited about 👇 2/ Another exciting development is the use of IMMUNE CHECKPOINTS, which can help boost the immune response against cancer by blocking proteins that prevent the immune system from attacking cancer cells.