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Cardiac Trials Profile picture
Cardiac Trials
@CardiacTrials
Simplified landmark cardiology trials app 📱 by Justin Sharim MD. Mission: to spread evidence-based medicine worldwide 🌎
Dec 20, 2025 • 7 tweets • 4 min read
2025 PRACTICE-CHANGING CLINICAL TRIALS #recap

~~ a thread 🧵 ~~ 👇 1/ DAPT following ACS revasc by CABG? The landmark CURE trial rendered DAPT as ACS standard of care in 2001. Recent trials challenge this dogma: this trial showed DAPT to hold no benefit over aspirin monotx, and (unsurprisingly) lead to ⬆️ bleeding. TACSI Trial, NEJM 2025 ♥️ Image
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Dec 26, 2022 • 7 tweets • 5 min read
2022 PRACTICE-CHANGING CLINICAL TRIALS #recap

~~ a thread 🧵 ~~ 👇 1/ SGLT2 inhibition initiation in the acute hospital setting? This trial showed significant benefit — REGARDLESS of ejection fraction — safe, and with incrementally added benefit when started early. EMPULSE Trial, Nature Medicine, 2022 ♥️ ImageImage