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Cell Reprogramming in Hematopoiesis and Immunity. @LuWcmm @Lund_Stem @lunduniversity. Tweets by Filipe Pereira (signed FP) and Malavika Nair (for CFP lab).
Sep 5, 2024 23 tweets 7 min read
1/23 We are excited to announce that our most recent study “In vivo dendritic cell reprogramming for cancer immunotherapy” was published in @ScienceMagazine.

Here is a summary of what we discovered!science.org/doi/10.1126/sc… 2/23 By delivering transcription factors PU.1, IRF8 and BATF3 (PIB), we successfully reprogrammed tumor cells in vivo within the immunosuppressive tumor microenvironment (TME) into antigen-presenting conventional dendritic cells type 1 (cDC1s) critical for robust immune responses Image