Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
Connor Payne Profile picture
Connor Payne
@Chemist_Payne
PD-Fellow @HarvardChanSPH. #Chemistry PhD @HarvardCCB. @UVMChemistry alumnus. #NSFGRFP fellow. Tweets my own. He/him.
Dec 10, 2021 • 7 tweets • 4 min read
On @biorxivpreprint we report a direct TR-FRET-based protein quantification strategy (<1 h from lysis➡️read) in unmodified cell lines. If you're into PROTACs, and you hate running Westerns, check it out! Mini-thread: (1/n)
biorxiv.org/content/10.110… Two birds with one stone: using clever biochemistry principles and a single POI-targeting antibody, we can rapidly & quantitatively measure both endogenous target engagement and protein levels in whole cell extracts, here exemplified for BRD4 (2/n)