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Chris Masterjohn Profile picture
Chris Masterjohn
@ChrisMasterjohn
PhD in Nutritional Sciences. Adding nuance to health science, using biochemistry to find your individuality.
30 subscribers
Jul 2 • 65 tweets • 8 min read
Nausea and Vomiting of Pregnancy Is Mitochondrial Dysfunction

The fascinating intersection between pregnancy and mitochondrial dysfunction and what to do about it.

🧵 Image Nausea and vomiting of pregnancy is a hypersensitive reaction to mitochondrial dysfunction in the mother in order to avert greater mitochondrial dysfunction in the more sensitive baby.
Jul 1 • 43 tweets • 5 min read
Introducing Mitome

Determine your "mitochondrial type" with my first-in-kind direct-to-consumer respiratory chain test that generates a personalized protocol. Image I'm excited to launch the first direct-to-consumer mitochondrial respiratory chain analysis and you can order it ​here​:

mito.me
Apr 19 • 8 tweets • 2 min read
The foundational origin myth of the "vaccines don't cause autism" cult is the retraction of the "fraudulent" Wakefield paper.

Just like Stalin erased Trotsky from photos of him and Lenin, they erase from history the larger 1996 Fudenberg paper that was never retracted. Published two years before Wakefield's paper, Fudenberg found that in 15 out of 22 autistics enrolled between 1984 and 1987, onset was within one week of the MMR vaccine. Image
Apr 13 • 35 tweets • 6 min read
Methylene Blue on the Airplane

…or underwater.

🧵 Image I talked to someone last night who said he uses methylene blue under two circumstances:
Apr 7 • 102 tweets • 11 min read
The Worst Longevity Idea Ever Conceived

The last thing you want to do is perpetually inhibit your mTOR.

🧵 Image Rapamycin is a darling of the longevity community.

I find it very hard to read the literature on this molecule without shuddering at the idea of taking it to lengthen lifespan.
Apr 3 • 21 tweets • 3 min read
My Oxalate Protocol

Oxalate causes crystals in the kidney, breasts, and brain, and is a powerful mitochondrial toxin that almost certainly shortens your lifespan and destroys your healthspan.

🧵 Image Do you have autism or have a friend or family member who has autism?

Oxalate levels are three times higher in autistics.
Mar 13 • 44 tweets • 6 min read
Why I Don't Care About Zone 2 Cardio

And what I do instead.

🧵 Image In 2022, inspired by Peter Attia’s interviews with Inigo San Millan, I experimented with measuring my lactate during exercise to calibrate my cardio to zone 2.
Mar 9 • 18 tweets • 2 min read
The Science Behind the Glycine Protocol

This is free for only 24 hours so read it now while you still have the chance!

🧵 Image Signs you need to pay attention to your glycine status to fix a health problem include any of the following: anxiety, poor sleep (lack of deep sleep, waking up in the middle of the night, trouble falling asleep or long sleep latency), poor memory...
Mar 2 • 45 tweets • 10 min read
Vitamins A and D have been a dominant force in infectious diseases throughout history, and their interactive, synergistic importance for optimizing immunity should be your central focus in not getting sick. 🧵 By the way, I haven't gotten a cold since I started creatine last year (currently on 8 grams), and this is despite being maximally unconscious around sick people to the point anyone would think I was crazy. This includes whatever is currently going around.
Feb 21 • 63 tweets • 8 min read
The Glycine-Oxalate Connection Your Doctor Isn't Testing For

Glycine is necessary for a long life, smooth movement, a calm mind, and stable blood sugar, but how would you know if it's too much?

🧵 Image 3 grams of glycine one hour before bed has been shown to reduce daytime sleepiness, help people fall asleep faster, and help people feel more rested and perform better cognitively during the day.
Feb 18 • 53 tweets • 6 min read
Why You Need to Start Juicing Tonight

The Sleep-Anxiety Connection Nobody's Talking About

🧵 Image If you have trouble sleeping, problems with anxiety, or get startled easily, I’ve got a quick solution for you, and it involves some green juice.

There’s about a fifty percent chance your problem is that your glycine levels are low.
Feb 7 • 56 tweets • 10 min read
Now that RFK Jr. has been caught spiking his drink with smurf oil, it's time to talk about methylene blue.

🧵 Two dropper fulls is probably 20 milligrams, assuming 1% solution with 20 drops per dropper. This is a high dose compared to what many in the biohacking community use, but a small dose compared to the ten times higher doses used in some clinical trials.
Jan 29 • 27 tweets • 5 min read
Support RFK Jr. For HHS Secretary

This is a once-in-a-lifetime opportunity to rein in the corporate stranglehold over medicine, health, and food, in the United States.

🧵 Image The RFK Jr. confirmation hearings for HHS Secretary have started today.

As with anything in politics, it’s going to be messy.
Jan 9 • 7 tweets • 2 min read
The Surgeon General is full of shit and can’t read a meta-analysis.

All but four types of cancer have inverse associations with light alcohol intake, no one has any clue what the causality is. There are as many cancers with a “no unsafe intake except zero” distribution as there are with a “only safe intake is zero” distribution.
Jan 7 • 54 tweets • 7 min read
The Biomechanics of Immune Dysfunction

This is the elephant in the autoimmunity and cancer room that EVERYONE IS IGNORING. Image As I covered in my Crohn’s Protocol, and The Science Behind the Crohn’s Protocol, the big elephant in the room in Crohn’s is that biomechanical dysfunction from joint misalignments is probably the missing ingredient in Crohn’s that no one is paying attention to.
Jan 4 • 8 tweets • 3 min read
The Science Behind the Crohn's Protocol

Anyone who has Crohn's or has a first-degree relative with Crohn's needs to understand the science of Crohn's and the extraordinary power of nutrition. Image Crohn’s disease is one of two disorders grouped together as inflammatory bowel disease (IBD), the other being ulcerative colitis. Ulcerative colitis exclusively impacts the colon, whereas Crohn’s can impact any part of the gastrointestinal tract from mouth to anus, though the ileum and proximal colon (that is, the last section of the small intestine and first section of the large intestine) are the most often affected. In ulcerative colitis, inflammation is limited to the mucosa, the mucus-rich superficial layer of the inside of the gut.

In Crohn’s, by contrast, the inflammation is considered “transmural,” meaning that it can be found in every layer of the gut tissue, but it is also characterized by “skip areas” where diseased sections of the gut are interspersed by normal healthy sections.
Jan 4 • 21 tweets • 3 min read
How to Heal From Crohn's Disease

This four-page quick guide is a complete strategy to induce and maintain remission from Crohn's disease using diet and supplements. Image Crohn’s disease impacts one to three percent of the population, and first-degree relatives of people with Crohn’s disease have a ten- to 20-fold risk of developing it in the future.
Nov 23, 2024 • 35 tweets • 4 min read
Sulfur Lies At the Crossroads of Obesity and Diabetes

Is sulfur behind your stubborn fat?

🧵👇 Image Obesity strongly predisposes to type 2 diabetes. This is not because fat storage promotes diabetes. Rather, it is because running out of room to store more fat causes diabetes.
Nov 16, 2024 • 22 tweets • 3 min read
How to Lose Fat Without Losing Muscle

NEVER start with cutting food intake!

🧵👇 Image When you “lose weight,” the health benefits you get are from losing fat.
Nov 4, 2024 • 43 tweets • 6 min read
Kennedy is right to stop the war on raw milk. Raw milk has unique health value destroyed by pasteurization and every American should have the right to drink it.

🧵 👇 Pasteurization primarily destroys the natural, healthy microbiome of the milk and a large portion of the whey protein.
Nov 3, 2024 • 4 tweets • 2 min read
Fluoride is not an essential nutrient.

Fluoride is a toxin that antagonizes iodine, which is essential to thyroid function, and thyroid during development is a major determinant of growth and IQ.

Fluoride makes mineralized tissues acid-resistant. This opposes tooth decay and in bones it causes defects in strength because acid-mediated bone remodeling is essential to making bones match the needs of their environment. Excess fluoride discolors and mottles teeth but bones are more sensitive to negative effects.

Animal experiments showing behavioral abnormalities in response to low levels of fluoride have been around for decades.

One of the early observations in support of fluoride was a low level of tooth decay in Hereford, TX, where there was a high concentration of fluoride in the water.

This was because they had 13 feet of glacial top soil that mineralized the plants with essential nutrients so well that they rejected all the fluoride and left it in the water.

The butterfat of their cattle was so nutritious that after sampling 20,000 butters across the world Weston Price decided to import all of his cream from that one place in TX. He used centrifuged butter oil from it — containing no fluoride — as part of a protocol to HEAL established dentin-infected cavities in his patients.

Teeth do not need fluoride. They never have. There has never been a good case for its essentiality.

There has always been a reasonable concern over its toxicity. Correction: 3 feet of top soil. Image