Christopher Vollmers Profile picture
Associate Professor at UC Santa Cruz. Mostly Genomics
Oct 31, 2021 5 tweets 4 min read
1/n Illumina But With Nanopore! New work from my lab led by all four of my graduate students @waddlingmind, @alexzee111, @MattAtoms, and @dorieD18. Ever had an Illumina library and wanted to sequence it right now but also kinda didn't want a ton of errors?
biorxiv.org/content/10.110… 2/n You can now do that on an ONT MinION. Just convert it with R2C2 first. You'll get accuracy and reads/$ comparable to Illumina iSeq/MiniSeq/MiSeq. We benchmarked this approach on RNA-seq, ChIP-seq, regular and targeted-enriched Tn5 libraries.