🚨 Alert! We are excited to share our new preprint in which we define the roles of individual class I molecules on brain endothelium in the regulation of T cell responses and development of neuropathology in experimental cerebral malaria
biorxiv.org/content/10.110… CD8 T cell engagement of brain vasculature has been implicated in the neuropathology of cerebral malaria. In this work we interrogated human and mouse data during infection and noted upregulation of activation and Ag-presentation molecules or transcripts in brain endothelium