@holmanm Statins block maturation of oligodendrocyte precursor cells and block myelination and repair of white matter fiber bundles throughout the brain. @holmanm This is a disaster for emotional self regulation through the uncinate fasciculus connecting the temporal lobe to the frontal lobe.

Here’s support for my ‘Myelin-Meltdown’ theory of myalgic encephalitis with cranio-cervical instability: “Sphingolipids (are) involved in…inflammation, cellular differentiation, regeneration, aging (&) musculoskeletal cells…The results of this study showed a dysregulation in sphingolipid metabolism, that could be associated with the reported symptoms: fatigue and muscular pain.” ncbi.nlm.nih.gov/pmc/articles/P… During and after neuronal inflammation and damage the sphingolipids are UP in serum levels but DOWN where they are needed for repair of the brain. The loss of elasticity is palpable in the brain and skull.

From Eric Topol: ACTH should increase if cortisol is low, but it didn’t, which tells us the Long Covid individuals have a hypothalamic-pituitary-adrenal axis (HPA) dysfunction. Low cortisol has been noted previously with chronic fatigue syndrome (ME/CFS) but this is the first report to reinforce its potential importance as an underpinning of Long Covid. But the basis for HPA dysfunction is unclear. Is it part of the neuroinflammatory process that can be a sequelae of a Covid infection? It should have been obvious to doctors that know anatomy that spike glycoprotein penetrated and glued shut adrenal fenestrations, hypothalamic fenestrations, and vagal nerve fenestrations at the brainstem.

You bring your PET scan. I'll bring my hands. To stop microglial inflammation and restore brain health minocycline must be distributed into the regions of post-inflammatory contraction. Your PET can't do that. jamanetwork.com/journals/jamap… Do you take a pill to fix a broken leg? What makes you think that minocycline alone will fix the brain? Monthly osteopathic cranial therapy, clemastine for oligodendrocyte myelin regeneration, sphingomyelin to bring/align new neurons, boromycin to chop spike protein polymers.

@Yash25571056 Spike protein is long-lived in the body. It can form sheets around organs and stiffen organ substructure and connective tissue. It affects collagen, hemoglobin, actin, myosin & 24 other important proteins other than the ACE2 protein. @Yash25571056 We have never had meningitis and bilateral temporal lobe inflammation in the brain in children at the same time. Every wave of Omicron penetrates the brain and causes demyelination. The brain glymphatic system is blocked by persistent meningeal thickening.

@DrMaureenHanson @Snipperspace @cstroeckw @Tempi_Stiftung It is not the family line of the virus. It is whether viral protein clogs the lymphatics at the base of the occiput. Clogged occiput increase intracranial heat. Inflamed myelin burns through the lymphatic plug. Then the muscle burn attacks the cervico-cranial ligaments. @DrMaureenHanson @Snipperspace @cstroeckw @Tempi_Stiftung After that ... the brain sags without the support of the cerebellum and the elasticity of the myelinated 'bungee cords' of the cerebellar peduncles.

"Viruses may be phagocytosed to different degrees by ...leukocytes and macrophages. The effect of phagocytosis may be virus inactivation, persistence, or multiplication; consequently, the result may be clearance of virus, transportation to distant sites, or enhanced infection." This is from Chapter 49 of Medical Microbiology 4th edition. Let's start over on the question "How well do white blood cells destroy Spike Protein?"

@loscharlos @ahandvanish Sphingomyelin is the molecule that coordinates regeneration of regions of the brain. Freeze-dried glandular "sphingolin" and "grassfed beed brain" were the only products I could find in 2021. If you want to test something for long-covid that you don't have to wait for ... @loscharlos @ahandvanish I had a mild but annoying vaccination reaction that crossed the blood/csf barrier and implanted in the medial wall of the left lateral ventricle. The inflammation filled the lateral ventricle then dropped down to the third and fourth venticle.

These White Matter Scans are what I asked Peter Marks MD - FDA Director of Vaccines - to study on 20 patients before final approval of MRNA Vaccines. Spike Protein Causes Myelin Meltdown. Red means 'Trouble'. I see frontal lobe and heavy subcortical damage.

Surprise! Spike Protein creates magnetic misfolding of protein in the brain. What do you think spike is trying to do to collagen protein polymer? Feel it 'Fold' and 'Twist' and 'Shrink'. ncbi.nlm.nih.gov/pmc/articles/P… "It Takes A Polymer To Beat a Polymer." Our Collagen can throw Spike Polymer to 'the mat' if we lend a hand. Spike polymer assemblies can be disassembled to restore organ health. But then we must help our body chop the individual spikes - & blow them up in white blood cells.

Robert Naviaux creates a symphony of science with flute sections of references culminating in a horn section of mitochondrial phases orchestrating a newly-named phrase for recovery. It is a masterpiece set against a backdrop of a toxic era. pubmed.ncbi.nlm.nih.gov/37120082/ Like every great synthesis created in the mind of a philosopher-biologist-psychiatrist it misses the hands-on grit of Dr. Andrew Still who brought us back to basics: makes sure the artery, nerve, and vein leading in and out of every organ is not obstructed. Wiggle & Slide.

Surprise! Covid incubates in the mucus and goblet cells of the small intestine indefinitely- and seeds spike and virus to the liver and throughout the body. presse.inserm.fr/en/covid-long-… Try palpating. The right small intestine stays swollen longer. Peristalsis is inhibited by spike binding actin beneath the microvilli. The portal circulation lifts the infection snd spike up to the uppef right liver.

Foolishness to call for retrospective symptom report from children instead of examining children by palpating their hot, swollen lateral ventricles, bulging skulls, and swollen livers during Omicron BA.1. jpeds.com/article/S0022-… The lateral ventricles in 90% of children I examined were swollen from 'horn' shape to cylinders and stayed hot for 8 weeks. From 8 to 12 weeks the walls of the ventricles were thickened as they shrank and twisted. Frontal lobe demyelination followed.

New wave of Covid, likely Omicron XBB.1.16, should give Long-Covid clinics a reason to examine their patients. Palpate LIVER, KIDNEYS & BRAIN to follow how long crucial Organs stay swollen. Sequelae of acute covid infection are determined by the long-lasting effects on specific organs in specific time periods .

Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection | bioRxiv biorxiv.org/content/10.110… Did I predict spike structure mutation changes? Hmmm. Lab research doesn't show the changes in the 'Propeller' region (moving loops in the 'chaotic' regions. And it doesn't consider the hydrodynamics of changing the shape of the 'prow' of the boat. Or oligomer patterns.

Four child patients and one adult this week with swollen, stuck, hot kidneys and cranial meningeal heat all across the top of the head. So I think these may be the pathognomonic signs of some new variant. Kidney swelling has not been an early-onset sign in other waves. Put a hand under the bottom ribs all the way medial to the spinal column. Then push your fingers up toward the head one inch more. The heat will come down into your fingerpads and define the kidney shape. And it won't wiggle much. But try 3 vectors and wait 5 minutes - with… twitter.com/i/web/status/1…

Long COVID: pathophysiological factors and abnormalities of coagulation - ScienceDirect. "Hooray!" But still they missed what we can learn from palpation of patients: "Spike Polymers interfere with Collagen Piezomagnetic Function." sciencedirect.com/science/articl… The endothelium (lining of blood vessels) is connected to the collagen of the basement membrane which surrounds all blood vessels. But there is a vast amount of collagen elsewhere throughout the organ structure and tissues of the body.

@CastAwayOne1 I treat vaccination reactions, vaccine-triggered illness, vaccine-expanded infection, vaccine- depleted immune system, vaccine-brain damage, myelitis, pericarditis, myocarditis. It is treatable once spike-protein polymer is recognized as the unitary 'novel' pathogenic agent. @CastAwayOne1 I recognised the massive scale of biophysical stiffness, heat, and uniform hardness of the frontal bone in the palpatory examination of my first patient in 2020.

Cry a little and drop to one knee to pray: 11 y.o. with hx. of chronic ear infection presents after psychiatric hospitalization for sudden surge in dramatic physical aggression. Classic long-omicron signs on exam: swollen right small intestine & right upper liver. Left temporal lobe entirely flattened from left lateral frontal lobe to anterior left occupit. Hypothalamic and bilateral vagus nerve nuclei brainstem fenestrations hot, tight & stiff. This is a temporal lobe blowout with spike protein polymer in the temporal and frontal bones.

"Since all glucocorticoids are not created equal, conclusions drawn from one glucocorticoid may not be equivalent to that of another glucocorticoid. Therefore, in-depth studies of each synthetic glucocorticoid to evaluate their specific pharmacological properties are warranted." ncbi.nlm.nih.gov/pmc/articles/P…

@a_dabbler @ahandvanish @ShaneyWright Treatment of a blown-out anterior left temporal lobe starts with liquid budesonide. Put a full drop in the left ear. It is an emergency. The ear canal is our closest access to the front of the temporal lobe. @a_dabbler @ahandvanish @ShaneyWright Give the patient 400 mg Vitamin C and 60 mg melatonin to start the repair of the ruptured blood-brain barrier and the torn meninges. The put the nebulizer mask on the patient and give 0.5 to 1.0 mg of budesonide mist. Encourage inhalation through the left nostril.