Multiple sclerosis patients see psychiatrists at triple the normal rate 12 years before symptoms
🧵👇 MS normally strikes out of nowhere - vision loss, mobility problems, sudden relapses.

But scientists wondered: is that dramatic first symptom really the beginning?

Frequent pornography use linked to altered brain connectivity and impaired cognitive performance.

Scientists compared college students who watch hours of porn weekly with light viewers.

Here’s what they found 🧵 Heavy viewers show a tighter sync between reward hubs & impulse-control cortex

Snap choices win, self-restraint loses

A psychopath's brain is strikingly different.

Their total brain volume is ~1.45 % smaller than that of non-psychopathic peers. 🧵👇 The volume loss concentrates in the brain’s impulse-control network.
- Frontal Cortex (Brain's 'impulse assessor')
- Basal Ganglia/Thalamus (The 'brake' itself)

Quality sleep is the foundation of health.

Yet a third of us are chronically underslept.

Here are 10 research-proven methods to transform your nights:
1. Keep a consistent schedule.
Same 30-minute window = 36% less insomnia. 2. Get morning light.

Just 10 minutes of bright sunlight within an hour of waking can shift your body clock by 30 minutes and boost your natural melatonin by 35%.

New study @NatureGenet identifies first genetic risk factor for long COVID.

They compared DNA from 16,000 patients vs 1.9 million controls across 24 countries.

Here are my key takeaways 👇 Key result: FOXP4 gene variant (rs9367106) increases long COVID risk by 60%

Microsoft claims their new AI framework diagnoses 4x better than doctors.

I'm a medical doctor and I actually read the paper. Here's my perspective on why this is both impressive AND misleading ... 🧵 What did they create? Two key innovations:
1. SDBench: A testing environment using 304 real medical mysteries from NEJM where AI starts with just "29yo woman with sore throat" and must decide what to ask/test next

2. MAI-DxO: An AI system that simulates 5 doctors working together as a team

CRISPR just scored its biggest win yet against Huntington's.

The secret? A delivery system called RIDE that sneaks into neurons, makes its edit, then vanishes in 72 hours.

Here's what happened 🧵👇 First - what is Huntington's?

Picture DNA as a sentence. In Huntington's, one word gets repeated too many times: CAG-CAG-CAG-CAG... This repetition builds toxic proteins that kill brain cells.

DeepMind just dropped a 106-page paper unveiling AlphaGenome.

This single model could completely redefine how we discover disease-causing mutations and drug targets.

This is massive. 🧵 The challenge?
>98 % of human variants lie in non-coding DNA which they exert INDIRECT regulatory effects on the proteins your body makes

I'm a doctor & neuroscientist - here's my hot take:

You already know what to do for your health.
Your real problem? Doing it.

So here’s my 10 hacks to create lasting habits:
1. Start tiny: 2 minute walk, 2 minute meditation. Your brain loves easy wins. 2. Link habits together: "After I make coffee, I'll review Spanish flashcards."

Attach new habits to things you already do. Studies show this doubles success rates.

I'm a doctor and neuroscientist.

The development i'm most surprised by: strategically limiting oxygen may be therapeutic.

A new @ScienceTM review showed that low levels of oxygen may be able to treat mitochondrial diseases and enhance stroke recovery.

Let me explain why 👇 In a stunning experiment, mice with a fatal childhood brain disease (Leigh Syndrome) lived 4x longer just by breathing less oxygen.

Instead of dying at 2.5 months, they lived nearly a year - and brain scans showed damage actually reversing.

While everyone was obsessing over CRISPR, a small team just quietly published a paper in Science solving genetic medicine's biggest problem.

They created a system that can fix thousands of different mutations at once. Here's how they did it 🧵 Current gene editing 101: You inherit a disease-causing mutation → CRISPR-Cas9 targets that exact DNA sequence → cleaves both strands → cell repairs it with correct template. Already curing sickle cell. Already reversing genetic blindness. Already changing medicine.