Microsoft claims their new AI framework diagnoses 4x better than doctors.

I'm a medical doctor and I actually read the paper. Here's my perspective on why this is both impressive AND misleading ... 🧵 What did they create? Two key innovations:
1. SDBench: A testing environment using 304 real medical mysteries from NEJM where AI starts with just "29yo woman with sore throat" and must decide what to ask/test next

2. MAI-DxO: An AI system that simulates 5 doctors working together as a team

CRISPR just scored its biggest win yet against Huntington's.

The secret? A delivery system called RIDE that sneaks into neurons, makes its edit, then vanishes in 72 hours.

Here's what happened 🧵👇 First - what is Huntington's?

Picture DNA as a sentence. In Huntington's, one word gets repeated too many times: CAG-CAG-CAG-CAG... This repetition builds toxic proteins that kill brain cells.

DeepMind just dropped a 106-page paper unveiling AlphaGenome.

This single model could completely redefine how we discover disease-causing mutations and drug targets.

This is massive. 🧵 The challenge?
>98 % of human variants lie in non-coding DNA which they exert INDIRECT regulatory effects on the proteins your body makes

I'm a doctor & neuroscientist - here's my hot take:

You already know what to do for your health.
Your real problem? Doing it.

So here’s my 10 hacks to create lasting habits:
1. Start tiny: 2 minute walk, 2 minute meditation. Your brain loves easy wins. 2. Link habits together: "After I make coffee, I'll review Spanish flashcards."

Attach new habits to things you already do. Studies show this doubles success rates.

I'm a doctor and neuroscientist.

The development i'm most surprised by: strategically limiting oxygen may be therapeutic.

A new @ScienceTM review showed that low levels of oxygen may be able to treat mitochondrial diseases and enhance stroke recovery.

Let me explain why 👇 In a stunning experiment, mice with a fatal childhood brain disease (Leigh Syndrome) lived 4x longer just by breathing less oxygen.

Instead of dying at 2.5 months, they lived nearly a year - and brain scans showed damage actually reversing.

While everyone was obsessing over CRISPR, a small team just quietly published a paper in Science solving genetic medicine's biggest problem.

They created a system that can fix thousands of different mutations at once. Here's how they did it 🧵 Current gene editing 101: You inherit a disease-causing mutation → CRISPR-Cas9 targets that exact DNA sequence → cleaves both strands → cell repairs it with correct template. Already curing sickle cell. Already reversing genetic blindness. Already changing medicine.