The comments & viewpoints are my own and are not endorsed or necessarily representative of UH CMC, CWRU, NCCN, FDA, NCI, or NRG. They are my personal opinion.
May 23 • 15 tweets • 7 min read
X-torial: Cleaning up the misinformation about @JoeBiden and #ProstateCancer that I am reading everywhere.
The purpose of this is to provide education from someone who treats and studies PCa for a living, lead the USA @NCCN PCa guidelines, hold leadership in @NRGonc @theNCI @US_FDA and dedicated my career to help men and their families suffering from PCa
@nytimes @WSJ @FoxNews @CNN @NBCNews @Reuters @ASCO @PCFnews @DeptofDefense
2/x PCa is not always an indolent disease. It remains the #2 cause of cancer death in men nearly every year. Men need screening. Kills more men every year than some of the most lethal cancers you can see on this list from the American Cancer Society for 2025.
@AmericanCancer @soulehoward1
Jun 4, 2023 • 9 tweets • 6 min read
#ASCO23 Tweetorial on putting results of PEACE-1 in context. Here we go!
Fallacy #1:
Dr. Ehdaie et al begin their reply by stating it is invalid to compare outcomes from pts treated 20-30 yrs ago.
Yet they cited data on positive post tx bx from data 30-40 years ago with low dose 2D and 3D RT.
@ParikhSimul@SprakerMDPhD Been absent on SDN and twitter mostly lately. Thanks for the good read. Here is my thoughts on COI as I have evolved over time and struggle given I have seen 1st hand when COIs cloud judgement. I also have seen those without expertise make incorrect interpretations.
Here we go...
@ParikhSimul@SprakerMDPhD 1/n I started my career declining all COIs. Was taught from med school they make you biased & pharma/industry were evil. I felt like I was pure & proud to have no COIs. Then I got to know people who worked for industry and those who transitioned from academics to industry...
Jul 5, 2022 • 6 tweets • 3 min read
@aj2279@NicholasZaorsky and myself wrote a quick commentary to @TheLancet for the @NRGonc RTOG 0534/SPPORT trial. Didnt make the cut so figured I would just post here if of interest to anyone.
Their word limit is crazy short.
May 14, 2022 • 16 tweets • 10 min read
1/n Too much noise, I figured it has been awhile since I did a tweetorial. Here you go for SSPORT/RTOG 0534
1st read up on the 1st RCT of SRT +/- hormone therapy (HT), RTOG 9601, and why men getting early SRT at low pre-SRT PSAs should NOT get ADT: jamanetwork.com/journals/jamao…
1/n I write this without knowing where to start, but what I know is I have a voice and that voice may reach people where other voices may not, or at least reinforce the voices of others.
After reading, listening, talking with those effected, here is what I know and what I dont
2/n Staying quiet, respectful, and polite is not enough. I need to actively be anti-racist. I need to actively be willing to relinquish power, and encourage others to as well to accelerate equality in America. Although some of that power was earned, much was also born into
Nov 3, 2019 • 15 tweets • 23 min read
1/
TWEETORIAL of GETUG-16 and hormone therapy with SRT
I have been asked many times to discuss this paper and my views on the topic now that the GETUG-16 was updated. It is a great trial with numerous strengths. So here we go… @MCWardMD@RTendulkarMD@subatomicdoc#PCSM@MCWardMD@RTendulkarMD@subatomicdoc 2/
Overall the trial can be viewed as positive or negative. How is this?
Original primary endpoint: PFS = was met!
Sample size was increased to be powered for OS, which was not met. So the endpoint the trial was actually powered for was not met = negative.
