The international society disseminating neonatal clinical research evidence: #ebneoalerts curate, #ebneoreviews appraise, #ebneopolls survey.
Dec 11, 2023 • 9 tweets • 3 min read
Bill Benitz from @StanfordChild reviews the published trial evidence for preterm PDA closure management
#HotTopicsNeo2023 #neoTwitter #neoEBM #PDA
Published PDA RCTs have been consistent in their findings of no benefit of PDA closure
Dec 7, 2020 • 6 tweets • 6 min read
Next up in "New Approaches to Cooling" Deirdre Murray of @CUH_Cork discussing “Neurodevelopmental Outcomes after Mild HIE.” Read more about Prof. Murray and her work: infantcentre.ie/who-we-are-2/o…
#HotTopicsNeo2020@HotTopicsNeo
Murray begins by defining the population discussed in her lecture: those with encephalopathy 2/2 perinatal asphyxia.
Last in the Rx for BPD trio at #HotTopicsNeo2020: Dr. Reese Clark of @MEDNAX with: "What Drugs are we Using? Practice Variability and Potential Harm." Read more about Dr. Clark's distinguished care: blog.mednax.com/mednax-neonato… @HotTopicsNeo
Reese: Talk to focus on steroid use. To begin, what postnatal steroids are we using? Dexamethasone and hydrocortisone most common systematic exposures, budenoside most common inhaled exposure.
Next up in #HotTopicsNeo2020: Erik Jensen of @ChildrensPhila discussing how the baseline risk of BPD impacts the number needed to treat when considering effective therapies.
@HotTopicsNeo
Presentation builds on recently published report in @JPediatr: drugs to Prevent Bronchopulmonary Dysplasia: Effect of Baseline Risk on the Number Needed to Treat jpeds.com/article/S0022-…
From the last session on periviability at @HotTopicsNeo, let’s get the pulse of the #neoEBM community with a few surveys (thread) #HotTopicsNeo2020
What is the earliest gestational age, assuming dating is correct, where you (or your hospital) routinely offer active postnatal resuscitation if desired by the family
Dec 7, 2020 • 5 tweets • 5 min read
First up in: "Pharmacotherapy for BPD: We Know Less than We Think We Do" at #HotTopicsNeo2020 is Dr. Gerri Baer (@thegerribaer), Team Leader for Neonatology @US_FDA, discussing "Challenges in Studying Drugs for BPD" @HotTopicsNeo#neoEBM
Baer: no (zero, zilch, none!) drugs approved in the USA to prevent or treat BPD.
Highlights various cohorts demonstrating the ongoing high burden of BPD:
Dr. Mikael Norman discuss care of periviable infants in Sweden #HotTopicsNeo2020
Changes in survival in Sweden, with survival at 22 weeks' gestation around 50% and increasing thereafter
Dec 7, 2020 • 8 tweets • 4 min read
Dr. Bührer discusses active care of tiny preterm infants in Germany #HotTopicsNeo2020#neoEBM
Highlights that this is a grey zone, where parental desires should be support
Dec 7, 2020 • 6 tweets • 2 min read
Dr. Joseph Kaempf shares data from a systematic review and meta-analysis on whether neurodevelopment outcomes are changing over time in extremely premature infants #HotTopicsNeo2020#neoEBM
The objective of the review was to evaluate within NICU or within cohort trends in NDI over time
PREMOD2 @NeoAnup's EBNEO Impact Article of the Year 2019 #HotTopicsNeo2020#neoEBM
So when deferred cord clamping is not thought to be feasible, is cord milking a suitable alternative in terms of severe IVH? #HotTopicsNeo2020#neoEBM
Are we paying too much for too little? @VPrasadMDMPH discusses the use of nusinersen for spinal muscular atrophy #HotTopicsNeo2020#neoEBM
Monthly costs for orphan drug prices for rare conditions
Dr. Trevisanuto @UniPadova shares evidence regarding its use for neonatal resuscitation. #HotTopicsNeo2020#neoEBM
Potential advantages of LMA use in neonates
Dec 6, 2020 • 10 tweets • 5 min read
Telemedicine for neonatal resuscitation? @jenfang0908 shares the opportunities #HotTopicsNeo2020#neoEBM
Can technology and telemedicine help close the gap in the mortality disparity for inborn and outborn infants?
Next up is Dr. Satyan Lakshminrusimha talking on systemic hypotension in PPHN. Satyan is a Professor and Pediatrician-in-Chief at UC Davis Children's Hospital, Department of Pediatrics. #HotTopicsNeo2019
A brief talk on the definition of hypotension, cardiac output, pre and afterloads. #HotTopicsNeo2019@HotTopicsNeo