Bicycle Therapeutics $BCYC has just fired a shot-heard-round-the-world, threatening to disrupt a huge technology platform in the biotech industry.

Here's a play-by-play on David vs. Goliath, taking on antibody-drug conjugates!

Thread below🧵 First, a little about Goliath:

Antibody-drug conjugates (ADCs) are antibodies (Ab) that target a specific cancer antigen on one end and are connected to a toxic payload (e.g. chemo) on the other end, acting as a biologic homing missiles. They work. Several are blockbusters.