We're excited to describe our research on how gene products are distributed in skeletal muscle! We began these studies with the goal of identifying distinct mRNA localization patterns in muscle, anticipating that mRNAs encoding sarcomeric genes might be locally translated
at the Z-disk. To our surprise, other mRNAs like Gapdh and Histone 1h1 were also there, and a great deal of nascent translation occurred along the sarcomere.