Eric T Wang Profile picture
Feb 27, 2021 11 tweets 5 min read
We're excited to describe our research on how gene products are distributed in skeletal muscle! We began these studies with the goal of identifying distinct mRNA localization patterns in muscle, anticipating that mRNAs encoding sarcomeric genes might be locally translated at the Z-disk. To our surprise, other mRNAs like Gapdh and Histone 1h1 were also there, and a great deal of nascent translation occurred along the sarcomere. ImageImage