Our paper on neoantigen evolution is out! nature.com/articles/s4158…
A great collaboration with @trevoragraham @marcjwills_ @jhouseham @wchcross @LuisglsZ @ara_anderson @research_junkie @cgatenbee @AndreaSottoriva @cssb_lab @BenjaminWerner_
More in thread: 1/ We set out to study the landscape of tumours and mutations when immune-associated negative selection drives tumour evolution. We asked what happens in a growing population, where tumour eradication and immune escape are both potential paths.