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Jonathan Afilalo Profile picture
Jonathan Afilalo
@FrailtyMD
Clinician scientist. Voracious learner. Director of McGill Geriatric Cardiology Program. Creator of https://t.co/PVflDwZCSD & https://t.co/4IJWOncQte.
Mar 24, 2020 • 5 tweets • 3 min read
ADHF +/- PNA

Acute Decompensated Heart Failure and Pneumonia are an increasingly concerning duo nowadays. How to distinguish one vs. the other vs. both? A mini #tweetorial Image Q: Prevalence of PNA in ADHF?
A: 21% (published range 15-30%)

Retrospective study of 1939 ADHF patients from 🇩🇪
- 21% had concomitant PNA (ICD-10 + CXR infiltrate)
- COPD and CKD were independent predictors
- PNA associated with 2x in-hospital mortality

journals.sagepub.com/doi/full/10.11… Image
Feb 10, 2019 • 9 tweets • 3 min read
#Tweetorial PIONEER-HF Trial: Angiotensin–Neprilysin Inhibition in Acute Decompensated Heart Failure pubmed.com/30415601 ▶️ Double-blind RCT at 129 US hospitals, ITT analysis
Jul 9, 2018 • 11 tweets • 5 min read
Had a chance to take a deep dive into a recent paper on #frailty in #TAVR by @glen_martin1 @mmamas1973 et al so I figured I'd share some thoughts tweetorial-style 🅿️ Patients: 2,624 TAVRs from the population-based UK registry... lucky them - 95 prospectively collected variables on all TAVRs in the land