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Giulia Boezio Profile picture
Giulia Boezio
@Giulsboezio
@EMBO @UKRI/MSCA postdoc @briscoejames @TheCrick 🇬🇧 || PhD @Stainierlab @mpi_hlr🇧🇪|| #devbio #scicomm enthusiast•• She/her 🇮🇹
Sep 30, 2020 • 11 tweets • 6 min read
I'm thrilled to share our story about the cellular crosstalk in the developing heart, regulated by TGF-β from the endothelial cells. Below more details and some beautiful #zebrafish hearts ⬇️. Coincidentally, it was out @elife exactly on #WorldHeartDay! ❤️elifesciences.org/articles/57603 When we mutated tgfbr1/alk5 in zebrafish, we found a very specific dilation of the cardiac outflow tract (OFT), resembling mammal aortic aneurysms...while all the other vessels and the heart looked unaffected. Occasionally, we even found ruptures and holes in the OFT!
Feb 1, 2020 • 4 tweets • 2 min read
This project, started with totally different aims, taught me that in every story there is something more, if you have the curiosity and the patience to look for it.
Intercellular communication regulated by TGFß in the #zebrafish cardiac outflow tract.⬇️ biorxiv.org/content/10.110… Impossible without the help, the discussions and the input of my amazing colleagues! #stainierlab
Thanks especially to @BensimonBrito and all the other coauthors!