Your low libido is not a Viagra deficiency.
Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

By now, there are many types of supplements and medications for erectile dysfunctions with things such as Viagra and Cialis being extremely popular.

These work by blocking PDE5 (or cAMP) and thus increasing cGMP levels.

cGMP is important for many things such as vascular tone, our eyesight, regulating ion channels, gut motility, the regulation of neurotransmitters, vasodilation and gluconeogenesis.

Fatigue? Gut issues such as SIBO? Low libido? Hair loss? Dry skin? High prolactin? Elevated cholesterol levels? Lactose intolerance? Cold intolerance?

Then consider looking into the thyroid.

Thread🧵 The thyroid gland governs our entire metabolism so we can't be very healthy if it's not functioning properly.

After all the thyroid gland directly communicates with the brain, the pituitary, the parathyroid, the pancreas, the liver, the adrenal glands and the intestinal system.

This is why i like to mention lactose intolerance as a possible symptom of thyroid issues since the thyroid facilitates the production of lactase in the intestinal tract.

So the thyroid gland affects way more processes than we could ever imagine.

Men with low testosterone levels have no energy or vitality, can't experience joy, have this undergoing anxiety for no apparent reason and their mental and physical performance are not that great.

So start with these if you are worried about your testosterone levels.

Thread🧵 Here’s a cool little axiom that you can use in order to objectively figure out how important something is:

Look at the life situation of the ones who do not have it.

In the case of androgens, men with issues such as low testosterone levels actually experience a true hell.

But unfortunately, since in this day and age men as young as 20 have testosterone levels of 300ng/dl they do not even realize that waking up tired, having no energy no matter what they try, being unable to have that God-given drive and so on, is not normal.

So even though testosterone is not the hot topic that it used to be (thank God), this does not mean that the low testosterone epidemic is over or that it won’t get worse (because it will).

There is a free and tremendously powerful tool that can improve and support every single aspect of our health called deep sleep.

So here's a thread on how to get deep sleep in case that's a struggle for you🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

Let's start with the "boring" stuff first.

Sleep is controlled by two processes: circadian and homeostatic.

During waking hours, the sleep drive gradually increases until it reaches a critical threshold.

This drive is referred to as homeostatic.

Just as with all health issues, gut issues are becoming more and more common.

So here are 15 things that could help you in your journey towards better gut health and better digestion overall if you're just starting out.

Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

First and foremost, if you are not sure about the state of your gut, here are some potential signs (obvious and not so obvious) that your gut might not be in good condition at the moment include:
-Bloating
-Heartburn
-Constipation
-Skin issues
-Ulcers
-Low energy
-Brain fog
-Gas
-Getting sick very
-Mood issues
-Dandruff
-Overeating
-Lupus
-Low testosterone
-Issues related to bone density and oral health
-Liver issues
-Too many simple carb cravings
-Nutrient deficiencies in things such as B12 (intrinsic factor relationship)

How can these be caused (and of course exacerbated) due to poor gut health, is not that hard to understand.

We have the gut-skin axis, the fact that our gut, makes up 60% of our total immune system and in general the links are well known at this point.
Examples:
…
…



journals.physiology.org/doi/full/10.11…
ncbi.nlm.nih.gov/pmc/articles/P…
pubmed.ncbi.nlm.nih.gov/35866234/
pubmed.ncbi.nlm.nih.gov/31386766/
pubmed.ncbi.nlm.nih.gov/30042740/
pubmed.ncbi.nlm.nih.gov/35625774/

Not paying attention to the health of your liver can negatively affect your gut, skin, sleep, energy levels, hormonal health and a lot more.

So here are 5 quick suggestions🧵 *Standard disclaimer that this does not constitute medical advice*

Let's start with the basics.

The liver is the second-largest organ in your body which is located in the upper right-hand part of your abdominal cavity underneath your diaphragm, right lung and rib.

It is made up of two main lobes which are made up of thousands of tiny lobules and each is made up of numerous hepatocytes.

These line up and between each row there are small blood vessels that diffuse oxygen and nutrients called sinusoids.

What you need to know about minerals in case you are interested in having better athletic performance, gut health, skin health, mood, hormonal health and a lot more.

Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

Minerals are one of the most important topics that need to be discussed since nowadays due to factors such as soil depletion, heavy metal exposure, herbicides, pesticides, antacids, endocrine disruptors and a lot of other things such as even phytic acid, a lot of people have some sort of mineral imbalance which is obviously a problem.

Phytic acid for example, prevents the leaching of nutrients out of certain plants such as grains, legumes, dark leafy green nuts and seeds which need to be sprouted or slow-cooked in animal fats in order for some of the phytic acid to be removed otherwise it will bind (mainly to) calcium and magnesium in the digestive tract and thus entirely prevents their absorption.

Food can often be the ultimate medicine.

In this thread, i will share with you some foods and herbs that can support your heart health🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice.

Of course, having a healthy heart doesn't only boil down to the consumption of these foods.

They can help and surprisingly quite a lot in some cases, but paying attention to your overall nutrition, getting your movement in and avoiding a sedentary lifestyle, getting sunlight, trying to mitigative stress and in general trying to support your heart through your overall lifestyle instead of isolated foods, will help you quite a lot.

Now let's talk about the food.

If you are experiencing histamine intolerance or you have symptoms such as skin issues, dry eyes, headaches and in general things that could be indicating histamine intolerance, start with this.

Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

First of all, what is histamine?

This monoamine affects our gut, sleep-wake cycle, certain hormones, appetite, the function of our pituitary gland and the overall function of our
metabolism.

It also regulates (the hypothalamic histamine) things such as oxytocin, b-endorphin, adrenocorticotropic hormone and prolactin.

And obviously it also affects our immune system since it regulates T cells, B cells and dendritic cells (for example, Th1 cells have a H1-R prevalence and Th1 cytokines are also associated with conditions such as atopic dermatitis).

It is also synthesized from histidine (or L-histidine to be more precise) through L-histidine decarboxylase which is expressed in mast cells, basophilis, parietal cells and the gastric mucosa. So basically histamine is formed through the decarboxylation of L-histidine.

.

Got dandruff?

In this thread, we will talk about some very common causes of dandruff (or things that can be mistaken for such) and what you can consider doing about them🧵 Of course, this will kind of be a holistic approach so take your time while reading it (you can even break it down in 2-3 reads) and remember that nothing in this thread should not be used as a substitute for medical advice.

We are trying to provide some insights, but at the end of the day if you are working with a M.D, he knows your situation better than us.

Now let's talk about the most common causes.

All health issues are affected by the gut.

So if you are struggling with gut issues, here are some things to consider.

Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

Just as with all health issues, gut issues are becoming more and more common and the reasons for this are clear if we understand what’s needed for a mechanism to be supported and what can cause its dysfunction.

So first and foremost, if you are not sure about the state of your gut, here are some potential signs that your gut might not be in a good condition at the moment include:

-Bloating
-Heartburn
-Constipation
-Skin issues
-Ulcers
-Low energy
-Brain fog
-Gas
-Getting sick very
-Mood issues
-Dandruff
-Overeating
-Lupus
-Low testosterone
-Issues related to bone density and oral health
-Liver issues
-Too many simple carb cravings
-Nutrient deficiencies in things such as B12 (intrinsic factor relationship)

I’m going to give you the first steps for your health journey.

Thread🧵 A crucial “preface”.

Number 1: This thread should obviously not be used as a substitute for medical advice.

Number 2: The health journey can seem boring but it’s really not.

The health journey is considered boring just because it got popularized with people who don’t have any other interests.

Over here, we view improving our health as a starting line and not a finish one.

We want to be healthy so we can be productive, be able to think properly and in general live life.

That being said if you’ve been reading my threads for a little while you will 100% be familiar with some of the material inside.

So you can either check out or use this thread as a reminder.

But since it’s becoming kind of clear that people who just started this journey followed me recently, i think that’s a good idea to make a basic thread about them.

Let’s get into it.

How your nutritional habits can negatively affect your testosterone levels.

Thread🧵 Disclaimer number 1: Nothing in this thread should be used as a substitute for medical advice.

Disclaimer number 2: Nutrition is of course crucial for our overall health, but only one of the parts regarding the things that support our health.

Optimal nutrition can only do so much if we do not get proper sleep, struggle with toxin accumulation, don’t train properly and so on.

We need to respect the fact that our bodies are very very complicated machines.

Steroidogenesis is affected by multiple factors and nutrition is only one of them.

The root cause of your overthinking could be hiding in your biology and not your "mind".

Thread🧵 Of course, just as with most problems, the issue of overthinking tends to be multifaceted and thus usually multiple things need to be addressed.

But in the case that you've tried practices such as limiting the amount of artificial stimuli that you expose yourself to, journaling, going for walks and so on, things that are all important and necessary in today’s society, maybe it's time to address the body and specifically the things that will be addressed over here.

Read this if the topic of nutrition seems confusing.
Thread🧵


*Standard disclaimer that nothing in this thread should be used as a substitute for medical advice

Nutrition can seem like a complicated topic if you’re just starting your health journey so this thread hopes to clear some things out.

First of all, have a clue about how many calories you consume but do not treat food as numbers on a screen.

It is extremely common nowadays for someone to think about food as numbers on a screen especially when starting to count his macros.

But food is not numbers on a screen, food is the fuel that provides us with the raw materials that our body needs in order to rebuild itself and its preparation was treated as something completely sacred in multiple cultures.

When you view food as numbers on a screen, you don’t even appreciate it and there’s something completely unnatural with this viewpoint.

Not to mention that you don’t even care about how it was sourced, the hidden effects that can have in your biology and multiple other things.

Calories matter 100% as stated, but they do not show you the full picture and only using a calorie meter to determine the response that your body will have to a food is wrong.

1) Why using Viagra to fix your low libido is idiotic (presented as simply as i can).

There are many types of supplements and medications for erectile dysfunctions with things such as Viagra and Cialis being extremely popular.

These work by blocking PDE5 (or cAMP) and thus increasing cGMP levels.

cGMP is important for many things such as vascular tone, our eyesight, regulating ion channels, gut motility, the regulation of neurotransmitters, vasodilation and gluconeogenesis.

It is derived from GTP (guanosine triphosphate) that is used in many pathways such as the ones in protein synthesis, and gluconeogenesis and its formation happens through the following steps:

Hypoxanthine (a purine derivative) -> PRPP (it’s formed by R5P and as a side note, thiamine, riboflavin, cobalamin and tryptophan depend on it) -> IMP -> GMP (or AMP) which then can be phosphorylated by ATP.

Another side note as well is that G proteins can bind to GTP in order for the alpha subunit to be activated.

Now a GTP molecule is also produced by the citric acid cycle which leads to the generation of one molecule of ATP with the help of NDK (the mitochondrial matrix in general is affected by both GTP and ATP).

So if the function of the citric acid cycle is harmed problems in the process that was just mentioned will happen.
2) When it comes to erections, cGMP is crucial since it regulates the activity of calcium channels and can allow the smooth muscles (corpus cavernosum) to relax which then leads to an increased blood flow.

These increased levels of cGMP and decreased levels of Ca2+ in the CC as a result of this, are a normal byproduct of the parasympathetic stimulation that enhances NO release (one of the reasons why stress kills erections) which leads to the activation of guanylate cyclase.

Also PDE5 targets cGMP that’s generated by NO.

So inhibiting PDE5 enchases the effects of NO which means that if NOs are not functioning properly inhibiting PDE5 won’t do much.

So things that inhibit PDE5 help and prolong an erection (in response to environmental stimuli) by enhancing the vasodilatory effects of cGMP.

Now PDEs = Phosphodiesterase isoenzymes

Isoenzymes basically are variants of the same enzyme that are encoded by homogeneous genes and have different amino acid sequences (this is what changes the electric charge of the enzyme).

Besides the specific form of phosphodiesterase (PDE5) that we care about over here, in the beta cells of the pancreas for example, glucokinase helps control the release of insulin, we also have cytochrome P450 isoenzymes that affect steroidogenesis and overall function of metabolism, then glutathione s-transferase is another isoenzyme that things such as bile acids and bilirubin bind and is thus involved in the metabolism of prostaglandins for example.

The 11 families of PDEs degrade cyclic-GMP and cyclic-AMP to GMP and AMP but also affect general cardiac contractility.

When it comes to PDE5, it can be found in things such as the heart cells or in general vascular, visceral smooth muscle and skeletal muscle, brain, kidneys, lungs and gastrointestinal tissue.

PDE5 matters in our conversation because it is responsible for the hydrolysis of cGMP in the tissues of the corpus cavernosum.

PDE5 and its three isoforms (PDE5A1, PDE5A2, PDE5A3 the first two can be found in the variety of the tissues mentioned but PDE5A3 is expressed only in the ones in vascular smooth muscle cells) degrade cGMP to 5’-GMP which makes an excess not only a problem for our libido but health in general.

Here’s what i would do if i had a problem when it came to my focus in order to not let this dysfunction prevent me from getting what i want but also ruin everything i’ve acquired👇

I got a glimpse the other day of what’s like not to be able to focus on something you want to do.

Not that fun.

And then i remembered that i have in fact also read every book on this topic because i had a problem with it.

But since it’s been so long since the last time i wasn’t able to sit down and focus on something i knew i should do, i almost totally forgot about it.

So if you have an issue regarding your focus, maybe the following rules will help.

But before we dive deep, two disclaimers.

First, nothing in here should be used as a substitute for medical advice.

Second, these rules are effective but not all of them will provide immediate results. The ones that address a bit more complicated causes when it comes to you not being able to focus will take some time but the effects are worth it.

Now let’s get into the rules.

Rule 1: When it's possible do the task that’s the least dopaminergic first thing in the morning.

Now this is tricky since the dopamine hit we get from a certain activity, is also affected by how much we care about it and enjoy it.

The classic examples of these are working out and reading.

If you HATE these two, then you will need a lot of “willpower” and thus it would be a good idea to do them first thing in the morning.

If you like these two, then you can do them whenever is the most convenient.

So basically, do what you hate but have to first thing in the morning when this is possible. Rule 2: Lay low regarding stimulants.

Stimulants, can in fact be beneficial regarding our focus since they make boring activities, less boring (no that’s where 70% of the benefits come from, you don’t need 1000mg of caffeine to do something you like) but here’s the problem.

Our brain is dumb. This means that if you sit down every day to work and consume 600mg of caffeine and 12 mg of nicotine, then it will become impossible to work without them if you do this for an extended period because our brain has linked this activity with MASSIVE dopamine hits.

So since most people do not work a lot on the weekends, at least try not to consume any stimulants on the weekend.

But also, if you want to quit them, this might be the best time since there’s more sun out and you won’t need to rely on stimulants that much. Even coffee consumption drops anywhere from 10-32% depending on the country during the summer.

But besides this, coffee can not fix the fatigue that springs from mitochondrial dysfunction and things such as sleep, quality nutrition, sunlight and so on are more effective than coffee. They just don’t provide an immediate boost and in the era of instant gratification, this leads to their neglect.

Now if you genuinely want to do something about your fatigue and not just mask it with stimulants, this might help.



Rule 3: Go for a walk without any artificial stimuli.

We live in a fast-paced society. But our brains are not meant to be that stimulated for that many hours with things such as emails, notifications, traffic, noise, social media, music etc.

We need to spend some time where we will let our brain and attention simply, rest.

Rule 4: Get some sleep.

This is probably one of the parts that most people will skip, but sleep always was and will always be a cornerstone for securing good levels of health.

We can not work around this fact.

Sleep deprivation causes a lot of serious problems with the most common ones being:
-Depression
-Fatigue
-Immune system dysfunction
-Myocardial Infarct
-Stroke
-Insulin resistance
-Vascular disease
-Hypertension
-Psychosis
-Diabetes
-Mood disorders
-Obesity
-Anxiety
-Neurological damage
-Skin aging
-Dark circles
-Vision problems
-Hypogonadism
-Hair loss
-Skin issues

All of which i assume you want to avoid.

Now, sleep is controlled by two processes: circadian and homeostatic.

During waking hours, the sleep drive gradually increases until it reaches a critical threshold. This drive is referred to as homeostatic.

Circadian rhythm, on the other hand, is a signal generated by the master clock, the suprachiasmatic nucleus (SCN) located in the anterior hypothalamus.

Circadian rhythm, derived from the Latin term “circa diem” which literally means “approximately one day” is the body's internal clock.

This clock is set at slightly over 24 hours. It controls sleep as well as most biological processes, including hormone production, metabolism, core body temperature variations, and cell regeneration among others.

This clock is normally highly synchronized to environmental cues such as the light-dark cycle and eating.

Disturbance of the circadian rhythm and homeostatic drive (circadian misalignment) can lead to various sleep disorders.

So, a lot of people today experience sleep problems and the problem is usually a dysregulated CR (circadian rhythm).

So here's how you can improve a possible circadian rhythm dysregulation.

Step 1: Avoid the main things that dysregulate our CR which mainly are:
-An unhealthy light environment
-Shift work
-Irregular sleep and wake up times
-Stimulants
-Alcohol
-Stress
-Working out too late in the day
-Frequent traveling and changing time zones

Step 2: Try the following:
-Wake up at roughly the same time every day.
-Expose yourself to natural light first thing in the morning.
-Have a healthy breakfast (do not skip this part thinking that's not that big of a deal).
-Do not have caffeine or any other stimulant for the first 90 minutes of the day.
-Do not do any form of intense exercise in the first 90 minutes of the day.
You can go for things such as walk obviously.
-Block the artificial blue light within reason throughout the day.
-Destimulate (at least) twice daily. Once for 30 minutes before bed (you can read a book for example) and once mid day if possible.
-Do not have huge meals late in the day.
-Ground throughout the day if possible.
-Manage your exposure to nnEMFs (especially during sleep)
-Roughly have the same bedtime and preferably before 11 p.m
-Try to avoid snacking unless you’re sensing that your blood glucose is too low.

Rule 5: No degeneracy and if you can’t use a particular social media platform to improve your life, don’t be on it.

In the first case, things such as pron are disastrous not only regarding focus but life in general and people who’ve struggled with it share stories about how their life significantly changed for the better once they quit.

Regarding social media, most people are of course used by them and they don’t use it.

Then if you find no beneficial use in a particular platform just don’t use it.

https://twitter.com/Helios_Movement/status/1763227461997805845

Seven rules for a healthy skin.
Thread🧵 *Standard disclaimer that nothing in this thread should be used as a substitute for medical advice*

Number 1: Eat a healthy diet.

This is the easiest one to address. Every cell in our body is made out of the things we eat and so our skin will be as well.

So, if you ingest garbage, your skin will be made out of garbage. As simple as that.

Now the proper diet past a certain point is based around the individual’s history and current conditions.

So, the following dietary guides are for a person who struggles with skin issues and they should not be mindlessly applied to any other issue as a jack of all trades.

Flu season is not over and if you find yourself getting sick pretty often, it would be a good idea to pay attention to the following.

Thread 🧵 *Obviously nothing in this thread should be used as a substitute for medical advice*.

Suggestion number 1: Provide enough of the following nutrients.

1. Vitamin D from sunlight.
2. Zinc from sources such as quality beef and seafood.
3. Vitamin C from sources such as acerola cherry, camu camu, berries and hibiscus.
4. B vitamins from quality animal products.
Besides vitamin D, B vitamins are also extremely crucial for T-Lymphocyte levels.
5. Vitamin E from sources such as EVOO or red palm oil.
6. Selenium from quality animal products (if you tend to get viruses very often, check the selenium content of your diet if you are getting enough sun).
7. Copper from sources such as quality shellfish, but do not over do it.

Everyone is tired these days but this doesn’t make chronic fatigue something normal.

So here are some common things that could be hiding behind it.

Thread🧵 First of all, you probably know that it takes a LOT in order to make a healthy organisms tired.

Just look at kids.
They are full of energy.

So tackling fatigue in most cases will require a multifaceted approach and this is what this thread proposes (nothing in it should be used as a substitute for medical advice).

Also, even though many of us work a lot, remember that this would not be possible if certain mechanisms such as our nutrition, sleep and so on were not at place.

No one is superhuman in the long run.

This is mentioned since, if you eat and sleep like crap, then no wonder why you work for 8 hours and feel like you just run a full marathon.

So keep in mind that the only ways to be able to work long hours and feel fine are either improving your health or various stimulants and other things that are usually worse.

The case of being overworked for years on end because you work two jobs or 15 hours a day for example won't be mentioned because guess what? These people don't spend time reading these threads.

Are you interested in living longer, having more energy, improved libido, improved sleep quality, better skin and hair health?

Well, then it’s time to dive into bee products.

Thread🧵
We’ve been aware of the almost countless benefits of bee products for thousands of years.

From the Egyptians and Romans all the way to the Babylonians, honey was consumed and utilized for a variety of issues.

But unfortunately, given that in this day and age a lot of focus is being put in synthetic substances since they have larger profit margins, these tools can be neglected.