Hugo Hilton Profile picture
Senior Associate @ThirdRockV. Formerly Maze Tx, @Calico and @Stanford.
Nov 22, 2019 12 tweets 4 min read
#PLOSBiology: Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian ... dx.plos.org/10.1371/journa…
Our article describing the immune system of the long-lived and cancer-resistant naked mole-rat published @PLOSBiology today. A brief(ish) thread 👇 The naked mole-rat is long-lived (~30y!) and doesn't seem to get cancer very often. But almost nothing is known about its immune system. In this study we used single-cell RNA sequencing of the blood and spleen to remedy that. Needless to say, we found some weird stuff....