~ The CCR5 Gene ~

The CCR5 gene encodes a chemokine receptor that plays a critical role in immune cell function, particularly in the recruitment and activation of T-cells and B-cells

Below, I’ll explain how CCR5 influences T-cell and B-cell production, its potential to drive increased production, and the risks associated with chronic overproduction of these cells 1. How CCR5 Impacts T-Cell and B-Cell Production

- Role in Immune Cell Activation and Recruitment:
CCR5 is expressed on T-cells (especially Th1 cells), B-cells, macrophages, and dendritic cells

It binds chemokines (e.g., CCL3, CCL4, CCL5), which guide these cells to sites of infection or inflammation

This signaling enhances the activation and proliferation of T-cells and B-cells by amplifying immune responses

For example, CCR5 signaling can promote T-cell differentiation into effector or memory T-cells and enhance B-cell activation, leading to antibody production

- Stimulation of Proliferation:
CCR5-mediated chemokine signaling can upregulate cytokine production (e.g., IL-2, IFN-γ), which supports T-cell clonal expansion and survival

This indirectly boosts T-cell production in lymphoid organs (e.g., lymph nodes, spleen)

For B-cells, CCR5 signaling enhances their migration to germinal centers, where they undergo proliferation and differentiation into plasma cells for antibody production

This is particularly relevant in response to infections or chronic inflammatory signals

- Microenvironmental Influence:
In lymphoid tissues, CCR5 helps create a microenvironment that supports T-cell and B-cell interactions with antigen-presenting cells (e.g., dendritic cells)

This fosters higher production of activated T- and B-cells during immune responses

*** COVID Accountability Victory: Court Rules in Favor of Healthcare Whistleblower ***

~ An update on US ex rel. Conrad v. Rochester Regional Health System. ~

By: WARNER MENDENHALL
@MendenhallFirm
JUL 17, 2025

• For 21 years, Deborah Conrad served as a dedicated Physician Assistant

• She was fired from Rochester Regional Health for doing her job - reporting adverse events to protect public safety

• A federal court vindicated her actions and opened the door for accountability

• On June 11, 2025, the U.S. District Court for the Western District of New York issued a landmark ruling for my client, Deborah Conrad, in her case against Rochester Regional Health and United Memorial Medical Center

• Judge Sinatra denied the hospital's motion to dismiss the core claims in Deborah's False Claims Act lawsuit, letting her case go to discovery

• Here's what this means:
The Court Found:

•Rochester Regional Health had a material obligation to report serious adverse events to VAERS under their Provider Agreement with the CDC

•The hospital's failure to report while continuing to seek federal reimbursement was potential fraud against the government

•Deborah's detailed allegations were enough to meet the strict legal standards for fraud claims, even without access to internal billing records

•Her retaliation claim can move forward - the court found she was probably fired for trying to expose the hospital's failure to report adverse events

• This decision establishes critical legal precedents:

1VAERS Reporting is Not Optional:

• The court confirmed that adverse event reporting requirements are "material conditions of payment" - not just bureaucratic paperwork

2Hospitals Can Be Held Accountable:

• Healthcare providers who take federal money while failing to meet safety reporting obligations can face False Claims Act liability

3Whistleblowers Are Protected:

• The court recognized that employees who try to ensure proper adverse event reporting are engaging in protected activity

• Deborah's case involved 170 serious adverse events that the hospital allegedly prevented her from reporting

• 160 VAERS reports she successfully submitted on her own initiative

• Specific patient examples of adverse events following vaccination that went unreported

• The court found these allegations painted a picture of systematic non-compliance with federal safety monitoring requirements

• This ruling is significant beyond just Deborah's case

• It establishes that:

1) healthcare providers cannot ignore federal safety reporting requirements while continuing to collect taxpayer money

2) the False Claims Act can be used to hold institutions accountable for COVID-related misconduct

3) whistleblowers who expose these practices have legal protection

• We estimate over 500,000 were killed by the shots, millions lost their jobs for refusing them, and Big Pharma received billions for dangerous and experimental treatments

• This case reveals a legal pathway to begin holding the system accountable

• The case now moves to discovery, where we will seek the hospital's internal “vaccination,” treatment, and billing records to uncover the full scope of unreported adverse events which we believe are in the 1000s in this hospital system alone
covidlawcast.com/p/covid-accoun… • First Amended Complaint: documentcloud.org/documents/2556…

Make Jumping Rope Great Again

oh and thank you God for mens Sweatpants ;)

enjoy this thread ladies and comment which one is your favorite

~<3 nurse Lynz

1~ A THREAD EVERY HUMAN BEING NEEDS TO READ & WILL AFFECT EVERY PERSON ON THIS PLANET REGARDLESS OF VACCINE STATUS ~

~> Amyloidogenic Fibrin Microclotting Following Prenatal mRNA Vaccination Exposure <~

*** HOUSTON, WE HAVE A PROBLEM ***

(@KevinMcCairnPhD)
05.24.25 at 20:59 2~ PREAMBLE: Houston, WE HAVE A PROBLEM!

•Scientific investigations involving emerging & potentially paradigm-shifting findings often walk a difficult line between the need for caution & the imperative to inform

• While early publication of case studies carries inherent risks—such as overinterpretation of individual data points or lack of statistical power—it also provides critical, time-sensitive insights that can drive new lines of inquiry & inform ongoing clinical & public health departments

• This report forms part of a robust, real-time investigation into the proteopathic & vascular consequences of prenatal exposure to mRNA-based SARS-COV-2 “vaccines”

• The intention is not to draw definitive epidemiological conclusions at this stage, but to publicly document the emergence of novel findings as they occur

• This transparent approach is particularly important in areas where existing safety literature has not yet integrated proteomic misfolding or amyloidogenic biomarker screening into its framework

• This investigative format mirrors the best practices seen in real-time pathogen tracking & pharmacovigilance

• In such contexts, timelines & transparency are essential for mitigating long-term risk & prompting refinement of public health frameworks

(@KevinMcCairnPhD)

~NOT SAFE & NOT EFFECTIVE: Full Evidence Dossier Packet~

*Prepared By: James Roguski* (@jamesroguski)

~Chapter 1: Evidence Dossier~
“The article discusses the urgent need for a global moratorium on COVID-19 mRNA vaccines due to their severe adverse events & unresolved safety concerns”

“The vaccines have been linked to a 6-fold increase in deaths, & their mechanism of action & potential harm are detailed in a comprehensive document”

“This free online resource provides EVIDENCE that the mRNA platform is a biological weapon delivery system & its ongoing & expanded use constitutes a grievous crime against humanity”

~ full evidence dossier packet below - use to follow along with this thread ~
(notsafeandnoteffective.com) ~ Chapter 2: A Letter to President Trump (@POTUS) ~

• Full Evidence here:
() open.substack.com/pub/jamesrogus…

🧵(1) ~ EDUCATION ~

💥 💥💥 The C19 mRNA ‘vaccine’ has been PROVEN to cause more Myocarditis cases than the C19 SARS-CoV-2 ‘synthetic virus’ 💥💥💥

TITLE OF ARTICLE
Myocarditis after SARS-CoV-2 infection & C19 vaccination: Epidemiology, outcomes & new perspectives

AUTHOR
Mead et al., International Journal of Cardiac Research & Innovation. Jan-Mar 2025, Vol. 3, Issue 1, pp. 1-43

FULL ARTICLE HERE
(doi.org/10.61577/ijcri…)
🧵(2)

ABSTRACT
Myocarditis, typically manifests as myopericarditis, is among the serious cardiac consequences observed over the course of the COVID-19 pandemic

We performed a comprehensive, evidence-based literature synthesis of findings from clinical trial data reanalyses, post-marketing surveillance, large observational studies & other diverse research sources that help shed light on the phenomenon of myocarditis post SARS-CoV-2 infection versus COVID-19 vaccine-induced myocarditis

Our conclusions refute several claims previously made by public health agencies & professional associations, namely the following:

1• the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) & Omicron infections have caused more cases of myocarditis than the COVID-19 mRNA immunizations

2• mRNA vaccine-induced myocarditis is typically mild, transient & rare, with no long-term sequelae

3• the risk-benefit calculus favors continued use of these products despite evidence of more iatrogenic cases

We address each of these misconceptions by applying a combination of clinical, epidemiological, & immunological perspectives

We URGE governments to remove the COVID-19 mRNA products from the market due to the well-documented risk of myocardial damage, a risk that is strongest for younger males (<40 years old)

KEYWORDS
• myocarditis
• pericarditis
• myopericarditis
• modified mRNA products
• vaccination
• SARS-CoV-2 infections
• cardiovascular disease
• adverse events
• risk-benefit analysis

are we ready for this conversation yet, yall?

mommy didn’t know because they lied to mommy

where are all of my momma bears out there who want to know the truth of what they have done to our children and young adults?

follow along, bc i’ll not only tell you the truth, BUT i’ll SHOW you the truth

ya’ll DESERVE to know the truth, regardless of how uncomfortable it is

~<3 nurse lynz @P_McCulloughMD @Jikkyleaks @jfvaughnmd09 @Fynnderella1 @PierreKory @jathorpmfm @JohnBeaudoinSr @MarbleBenjamin @NicHulscher @McCulloughFund @ChildrensHD @Honest_Medicine @MdBreathe @drpaulmarik1 @DrJackKruse @Kevin_McKernan @KevinMcCairnPhD @molsjames @KLVeritas

follow these accounts for truth too

1 ~ FAKSOVA ET AL: (n=99 million participants)

“COVID-19 Vaccines & adverse events of special interest: A Multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals”

:KEY POINTS:

~Myocarditis rate: (+510% increase after mRNA shot)

~Acute Disseminated Enchephomyelitis: (+278% increase after mRNA shot)

~Cerebral Venous Sinus Thrombosis: (+223% increase after viral vector shot)

~GBS/Guillain-Barre Syndrome: (+149% increase after Viral vector shot)

pubmed.ncbi.nlm.nih.gov/38350768/ 2 ~ RAHELEH ET AL: (n=85 million participants)

“COVID-19 Vaccination & Cardiovascular Events: A Systematic Review & Bayesian Multivariate Meta-Analysis of Preventive Benefits & Risks”

:KEYPOINTS:

~Heart Attacks: (+286% increase after 2ND DOSE)

~Stroke: (+240% increase after 1ST DOSE)

~Coronary Artery Disease: (+244% increase after 2ND DOSE)

~Cardiac Arrhythmia: (+199% increase after 1ST DOSE)

pubmed.ncbi.nlm.nih.gov/40191438/

Yayy! it’s finally Published and peer Reviewed yall!

congratulations to @brucep13 & @dryostradamus and thank you for all you do and continue to do to actually help the injured and not profit off of or abandon us

the first sentence makes my heart smile that it doesnt say the vaccine has saved millions of lives - bc it didnt

in case yall didnt know this is the real work that Yale used to do their Listen Study with

Dr Patterson and Dr Yo’s entire group were censored and silenced in 2021 due to bullying, threats and harassment from ngo funded pharma agents - their preprint was blocked and never saw the light of day

Yale used their work in the listen study and yales preprint confirmed Dr Pattersons work- RFK took over HHS secretary and now the scientific publication world is being investigated for what i mentioned above -

Pattersons paper is now peer reviewed and it echoes my labs to a T (see below)

SO IM CELEBRATING WITH YALL ON THIS ONE - THIS IS HUGE WIN AND MAKES MY HEART SMILE

@MarieAngelaW1 @C19VaxInjured

tandfonline.com/doi/epdf/10.10…
@dryostradamus & @brucep13 im crying tears of joy for yall right now

love yall

~<3 nurse lynz

im on day 1590 now of continuous spike production

—> Layman-Friendly Explanation of: DNA Contamination and Its Impact on the Immune System <—

educational thread put together via @Nicolina0815 <3

• The DNA impurities (linear DNA and plasmids) found by @Kevin_McKernan in mRNA vaccines are like unwanted blueprints that sneak into our cells

• They cause a chain of problems that confuse the immune system by messing up important signals and cells

~> follow the thread below to see how it works step by step <~ 1 —>DNA Contamination Activates STAT3 & IL-6 <—

• The foreign DNA is spotted by immune cells (like dendritic cells or macrophages): it views it As if it’s an invader

• This flips on the STAT3 signal: Which acts like a switch that turns on inflammation

• STAT3 makes cells pump out IL-6: A messenger that stirs up inflammation

~> Why is this a problem <~

• IL-6 is like a fire alarm: A little is fine to wake up the immune system, but too much causes chaos ~> (My IL-6 is 48 & normal range is 1-3)

• The DNA (often wrapped in lipid nanoparticles): Keeps this alarm blaring because it doesn’t break down quickly

Was amyloidogenic prions (aka Mad Cow Disease & Chronic Wasting disease) on your BINGO card?

Vax status at this point doesn’t matter bc this will affect every single person in this planet and once the public grasp this - maybe then once realized we can come together as one to fight this monster we are facing

The blood and plasma is contaminated as well and there are no more Pure bloods im sad to say

STOP THE SHOTS NOW

I’ll post below how we can test your blood via @KevinMcCairnPhD Protocol on sending blood samples for amyloid fibrin clot assessment and RT-quic option as well

https://twitter.com/houselyndseyrn/status/1881748500054204831

Ralph Baric: @Heysenberg40737

Criminal Evidentiary Dossier



SARS-Cov Patent - Baric UNC CHAPEL HILL : methods for producing recombinant virus

SARS-CoV Patent History

NIH funded Barics Research

Fauci-NIH funding of Barics Research Prosecutenow.io


REMDESIVIR funding

NIH funded REMDESIVIR research at UNC CHAPEL HILL (2017-2021)

NIH-WHO Ebola Virus Human Trial in DR Congo: Four experimental therapies

Dr Baric: REMDESIVIR human clinical trial in DR Congo

My best friend looking at me when @TrialsiteN threatens and slanders 2 protected whistleblowers in a SLAPP BACK law state in an article by an independent anonymous journalist labeling us as “Nihilistic Antivaxxers or Deep state trolls” -

& not to mention one of those whistleblowers is also a patient and a disabled, confirmed, documented and diagnosed vaxinjured RN that’s in the study who got retaliated against bc they posted their own lab results and asked where’s the data and who they sold it to

@Jikkyleaks - “they not like us”

#YaleGate x.com/jikkyleaks/sta… x.com/jikkyleaks/sta…

@Jikkyleaks @hmkyale @medrxivpreprint @YaleMed @VirusesImmunity Cowards and criminals block

Answer the question

Where did my data go and who did you sell it too @Jikkyleaks @hmkyale @medrxivpreprint @YaleMed @VirusesImmunity We need answers - bc my labs alone debunked your entire study

https://twitter.com/houselyndseyrn/status/1893081833530892582

#YALEgate

https://twitter.com/jikkyleaks/status/1893561937805574422

x.com/houselyndseyrn… x.com/houselyndseyrn…

The “Lyndsey Smear Campaign” is under way

Block ignore and don’t engage

Im their number one target and they want a reaction

Let them expose theirselves

All posts and space recordings are being collected and handed over to the international human rights lawyers and they can all be charged & prosecuted for the slander individually

These people hate the truth, lie and will do what it takes to silence me

GOD is on my side and the cells don’t lie

That’s all. Carry on <3 @SecKennedy @FBIDirectorKash @Kash_Patel @RobertKennedyJr @PamBondi @PressSec @FLOTUS @realDonaldTrump @POTUS @Bannons_WarRoom @MELANIATRUMP @TrumpWarRoom @TulsiGabbard @x @Safety @FBI @DOGE_HHS @HHSGov @elonmusk @DOGE @cb_doge @C__Herridge @catturd2 @Jikkyleaks @Fynnderella1 @RobManess @winterofsicknes @ColonelTowner @patriot_savvy
@ShannonJoyRadio @ReportAdve30828 @negar_harari
Please see above

So the Yale Listen Study said 709 days per their testing of vaxinjured still having continuous spike production (which I am a participant in this study) and show T cell exhaustion etc

Well it’s actually longer than that:

My first injection was 12/23/2020 and I haven’t stopped producing spike and it’s now 02/21/2025

8 months after my 2 Moderna injections I still had large amounts of spike detected per antigen testing- & I’ve never had Covid( results below)

That’s 1,521 days - of continuous spike protein production with NO OFF SWITCH since my first injection & STILL in my body to date

Let that sink in!

(3 years worth of Cytokine 14 panels & S1 immune subset panels below)

I am a documented, confirmed & diagnoses Adverse reaction to MRNA vaccine ( T50.B95A)

Full take consent form:

*Persistence of S1 Spike Protein in CD16+ Monocytes up to 245 Days in SARS-CoV-2 Negative Post COVID-19 Vaccination Individuals with Post-Acute Sequalae of COVID-19 (PASC)-Like Symptoms*

Via: Bruce K. Patterson, Ram Yogendra, Edgar B. Francisco, Emily Long, Amruta Pise, Eric Osgood, John Bream, Mark Kreimer, Devon Jeffers, Christopher Beaty, Richard Vander Heide, Jose Guevara-Coto, Rodrigo A Mora-Rodríguez

doi: doi.org/10.1101/2024.0…

{this is the preprint they refused to publish unless they took the vaxinjured data out- MY DOCTOR WHO DIAGNOSED & SAVED ME IS AN AUTHOR}

• ABSTRACT •
There have been concerning reports about people experiencing new onset persistent complications (greater than 30 days) following approved SARS-CoV-2 vaccines (BNT162b2 (Pfizer), mRNA-1273 (Moderna), Janssen (Johnson and Johnson), and ChAdOx1 nCoV-19 (AstraZeneca))

We sought to determine the immunologic abnormalities in these patients and to investigate whether the potential etiology was similar to Post-Acute Sequalae of COVID (PASC), or long COVID

We studied 50 individuals who received one of the approved COVID-19 vaccines and who experienced new onset PASC-like symptoms along with 45 individuals post-vaccination without symptoms as controls

We performed multiplex cytokine/chemokine profiling with machine learning as well as SARS-CoV-2 S1 protein detection on CD16+ monocyte subsets using flow cytometry and mass spectrometry. We determined that post-vaccination individuals with PASC- like symptoms had similar symptoms to PASC patients

When analyzing their immune profile, Post-vaccination individuals had statistically significant elevations of sCD40L (p<0.001), CCL5 (p=0.017), IL-6 (p=0.043), and IL-8 (p=0.022)

Machine learning characterized these individuals as PASC using previously developed algorithms

Of the S1 positive post-vaccination patients, we demonstrated by liquid chromatography/ mass spectrometry that these CD16+ cells from post-vaccination patients from all 4 vaccine manufacturers contained S1, S1 mutant and S2 peptide sequences

Post-COVID vaccination individuals with PASC-like symptoms exhibit markers of platelet activation and pro-inflammatory cytokine production, which may be driven by the persistence of SARS-CoV-2 S1 proteins in intermediate and non-classical monocytes

The data from this study also cannot make any inferences on epidemiology and prevalence for persistent post-COVID vaccine symptoms

Thus, further studies and research need to be done to understand the risk factors, likelihood and prevalence of these symptoms

Summary: SARS CoV-2 S1 Protein in CD16+ Monocytes Post-Vaccination

• Footnotes •
Abbreviations: PASC, post-acute sequelae of COVID-19; POVIP, post-vaccination individuals with PASC-like symptoms; NCM, non-classical monocytes; IM, intermediate monocytes; CX3CL1, C-X3-C motif chemokine ligand 1; CX3CR1, C-X3-C motif chemokine receptor 1; IL, interleukin; RANTES, regulation on activation, healthy control T-expressed and secreted; CCR, chemokine receptor; IFN, interferon; TNF, tumor necrosis factor; MIP, macrophage inflammatory protein; PBMCs, peripheral blood mononuclear cells; VEGF, vascular endothelial growth factor; LH, long hauler or PASC

• Paper in collection : COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv connect.medrxiv.org/relate/content…
• INTRODUCTION •
Despite over 13 billion doses of SARS-CoV2 vaccines being administered to individuals worldwide, there have been concerning reports and publications of persistent adverse effects of the COVID-19 vaccines

These reports suggest that new-onset cardiac, vascular and neurological symptoms commenced within minutes and hours after vaccination and subsequently, were persisting for months and years 1–5

Interestingly, many of these persistent post-vaccine symptoms are similar to symptoms associated with post-acute sequelae of COVID (PASC), or long COVID

We recently reported that the S1 protein subunit of SARS-CoV2 was persistent in both nonclassical (CD14- CD16+) and intermediate (CD14+CD16+) monocytes several months and years after acute infection and could be a possible pathophysiological explanation for PASC

Interestingly, the BNT162b2 (Pfizer), mRNA-1273 (Moderna), Janssen (Johnson and Johnson), and ChAdOx1 nCoV-19 (AstraZeneca) vaccines also deliver a synthetic S1 protein subunit directly into muscle cells to elicit an immunological response

Since there were similarities between PASC and persistent post-vaccination symptoms in individuals who never had a history of COVID infection, we sought to study if persistent S1 proteins were also present in CD16+ monocytes of both groups

One of the challenges in studying individuals with persistent post-vaccination symptoms is the lack of approved confirmatory tests to rule out previous infection or exposure to SARS-CoV2

Hence, we used a combination of patient clinical history, negative anti-nucleocapsid antibody testing and T-detect testing as a way to screen these patients

Here, we report on 50 individuals with symptoms >1 month following vaccination (with either Pfizer, Moderna, Johnson and Johnson or AstraZeneca) that resembled the spectrum of symptoms reported in long COVID or PASC7

We used machine learning to analyze the immune profiles in these individuals

Further, we used high parameter, single cell analysis to determine if S1 protein generated by vaccination persisted in immune cells as previously described

• Per FOIA •

• THE DOD CONTRACT WITH PFIZER •

Have a good day!

<3

(1) ~ A MUST READ THREAD/PART 1 of 2 THREADS (1/25)

** Would you Like “Turbo Cancer” with that? **

~The “Turbo Cancer is a myth” MYTH is a low point, even for big pharma cartel and their pseudoscience cronies~

* By: Arkmedic Substack *

• Today’s article is hopefully going to answer the question about whether "Turbo Cancer”

(a) exists
(b) is a consequence, or possible consequence of the imposition of a genetic vaccine platform on the global population

.@Jikkyleaks. (2) ~ “Turbo Cancer is a Myth: Via Wikipedia” ~

• The first thing that needs clearing up is “where did the Turbo Cancer phrase come from?”

• If you’re in the field you might think this is a made up term, but it really exemplifies the idea of a rapidly progressive cancer, that is progressing or spreading much faster than you would be used to

• Most oncologists know how the cancers they treat progress and so can give you an idea of what to expect

• A prostate cancer in an elderly person for instance would normally take years to progress, so getting growing secondaries in a few months would be unusual

• Similarly for a small breast cancer that was surgically removed or treated with radiotherapy which would be expected to be cured with the first line of treatment

• So you would think “Turbo Cancer” would be embedded in the oncologists lexicon from old, but it isn’t

• In fact the first mentions were coming from Twitter/X the end of 2022 and beginning of 2023:
x.com/search?q=%22tu…

• Here is Dr Charles Hoffe talking about it back in January 2023 as a relatively new phenomenon below:

(1) • OCTOBER TERM, 2012 •

— Syllabus —
NOTE: Where it is feasible, a syllabus (headnote) will be released, as is being done in connection with this case, at the time the opinion is issued

The syllabus constitutes no part of the opinion of the Court but has been prepared by the Reporter of Decisions for the convenience of the reader

~ See United States v. Detroit Timber & Lumber Co., 200 U.S. 321, 337 ~
SUPREME COURT OF THE UNITED STATES

• Syllabus •
ASSOCIATION FOR MOLECULAR PATHOLOGY ET AL. U. MYRIAD GENETICS, INC., ET AL.

CERTIORARI TO THE UNITED STATES COURT OF APPEALS FOR
THE FEDERAL CIRCUIT

No. 12-398. Argued April 15, 2013—Decided June 13, 2013

• Each human gene is encoded as deoxyribonucleic acid (DNA), which
takes the shape of a "double helix."

• Each "cross-bar" in that helix
consists of two chemically joined nucleotides

• Sequences of DNA nucleotides contain the information necessary to create strings of amino acids used to build proteins in the body

• The nucleotides that code for amino acids are "exons," & those that do not are "introns."

• Scientists can extract DNA from cells to isolate specific segments for study

• They can also synthetically create exons-only strands of nucleotides known as complementary DNA (cDNA)

• DNA contains only the exons that occur in DNA, omitting the intervening introns

• Respondent Myriad Genetics, Inc. (Myriad), obtained several patents after discovering the precise location & sequence of the BRCA1 & BRCA2 genes (breast & ovarian cancer genes), mutations of which can dramatically increase the risk of breast & ovarian cancer

• This knowledge allowed Myriad to determine the genes' typical nucleotide sequence, which, in turn enabled it to develop medical tests useful for detecting mutations in these genes in a particular patient to assess the patient's cancer risk

• If valid, Myriad's patents would give it the exclusive right to isolate an individual's BRCA1 & BRCA2 genes & would give Myriad the exclusive right to synthetically create BRCA cDNA

• Petitioners filed suit, seeking a declaration that Myriad's patents are invalid under 35 U.S. C. §101

• As relevant here, the District Court granted summary judgment to petitioners, concluding that Myriad's claims were invalid because they covered products of nature

• The Federal Circuit initially reversed but on remand in light of Mayo Collaborative Services v. Prometheus Laboratories, Inc., 566 U.S. — the Circuit found both isolated DNA & cDNA patent eligible (2) Cite as: 569 U.S. _ - (2013)

• Syllabus •

(c) DNA is not a "product of nature," so it is patent eligible under §101

• cDNA does not present the same obstacles to patentability as naturally occurring, isolated DNA segments

• Its creation results in an exons only molecule, which is not naturally occurring

• Its order of the exons may be dictated by nature, but the lab technician unquestionably creates something new when introns are removed from a DNA sequence to make cDNA Pp 16-17

(d) This case, it is important to note, does not involve method
claims, patents on new applications of knowledge about the BRCA1 & BRCA2 genes or the patentability of DNA in which the order of the naturally occurring nucleotides has been altered Pp. 17-18 689 F 3d 1303, affirmed in part & reversed in part

• THOMAS, J., delivered the opinion of the Court, in which ROBERTS, C. J., & KENNEDY, GINSBURG, BREYER, ALITO, SOTOMAYOR, & KAGAN, JJ., joined & in which SCALIA, J., joined in part

• SCALIA, J., filed an opinion concurring in part & concurring in the judgment