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Marvin Hsiao Profile picture
Marvin Hsiao
@HsiaoMarvin
🇹🇼🇿🇦Clinical virologist @nhls_sa, A/prof @UCTHealthSci, clueless dad, and lifelong gamer. Aspire to be useful.
Apr 1, 2022 • 5 tweets • 1 min read
In post-4th wave 🇿🇦 interpreting surveillance data is really challenging. In addition to the decoupling of death and cases, we also have decoupling of wastewater viral load and symptomatic cases. In the case of recent peak in wastewater, our cases had been relatively static 1/n As level of prior immunity increases proportion of asymptomatic and mildly symptomatic individual became high. Although these people can still infect others, they have little reason to seek testing and thus not reflected in our case data. 2/n
Jan 15, 2022 • 8 tweets • 5 min read
Our other Western Cape paper of omicron clinical severity pre-print is now out on Medrxiv. medrxiv.org/content/10.110… In this study, we used a PCR proxy marker similar to SGTF in Taqpath assay (approached used in Wolter et al.) to assess risk for hospitalisation among some public sector cases in Western Cape. As the Taqpath assay is rarely used here, we used a different approach. 2/
Dec 30, 2021 • 13 tweets • 2 min read
Casual observation around people I know during 4th wave: re-infection>first infection. This bucks the trend from previous waves. What does this mean? 🧵 1/ Let's get the obvious out of the way: A lot of people had been infected in previous waves. So eventually the trend of re-infection vs first time has to change. I was just surprised it is so soon. 2/
Dec 28, 2021 • 4 tweets • 1 min read
Our short pre-print on Saliva swabs are the preferred sample for Omicron detection medrxiv.org/content/10.110… Compared to Delta where saliva samples had substantially higher Cts, there is no difference between Cts of omicron saliva samples and nasal swab. Image
Dec 6, 2021 • 19 tweets • 6 min read
I tweeted this yesterday literally hangry and waiting for my takeaway food. Time for a more considered thread on discrimination, failures, empathy and way forward. 1/n First let's just get this out of the way. I nearly threw my phone when I saw this. Everyone needs to call out this kind of racist, discriminatory BS for what it really is. No one here thinks it's clever or funny. 2/n
Nov 25, 2021 • 10 tweets • 3 min read
It’s been an intense and frantic week. I am exhausted but can’t sleep so might as well tweet about my thoughts on B.1.1.925 1/n First the incredible duo @Tuliodna @rjlessells gave a really good media briefing. If you have not watched it it is worth your time. 2/n
Sep 11, 2021 • 9 tweets • 4 min read
So there is a point to this seemingly flippant poll. As a country, we have spent at least R8.5 billion in (essentially unbudgeted health expenditure) in Covid testing. How much more money do we have to pay the shareholders of these big first world diagnostic test companies. 2/n