We enjoyed the first one so much, we thought we'd go again. Our second #WorldEBHCDay #Tweetorial we want to showcase is the infrequent times when you may need to upgrade the certainty you have in your evidence when following the #GRADE approach @JBIEBHC @WorldEBHCDay (1/8) Evidence from observational studies and non-randomised experimental studies is (under most-circumstances) initially classified as low. However, there are rare occasions when these studies may provide higher than low certainty in the evidence #Tweetorial #WorldEBHCDay (2/8)

For #WorldEBHCDay we wanted to share our first #Tweetorial about the 5 determinants to consider when downgrading the certainty that we have in our evidence from RCTs when following the #GRADE approach @JBIEBHC @WorldEBHCDay (1/8) Certainty in the evidence starts as high when following the #GRADE approach. However it may be necessary to downgrade the certainty in this evidence. We do this by assessing the following 5 determinants Guidance: shorturl.at/qxB68 #Tweetorial #WorldEBHCDay (2/8)