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Jasmine Sukumar MD Profile picture
Jasmine Sukumar MD
@JasmineSukumar
Breast Medical Oncologist @MDAndersonNews. Alum of @UTSWInternalMed, @OSUCCC_James #bcsm, views are my own.
Sep 21, 2022 • 19 tweets • 126 min read
@TumorBoardTues 1/17 #TumorBoardTuesday #bcsm

CASE: 55 yo post-menopausal 👩🏽
🚫comorbidities
HR+/HER2- MBC
🦴metastases, on letrozole+palbociclib 2 yrs
🩻Scans: progression in liver
🔬Liver biopsy: ER 90% PR 90% HER2- (IHC 1+)
Tissue NGS➡️ESR1 & PIK3CA mutation

🤨What 2L tx do you recommend? @TumorBoardTues 2/17 #TumorBoardTuesday #BCSM #OncTwitter

🤨 What is the prevalence of PIK3CA activating mutations in metastatic HR+/HER2- breast cancer?

@Dr_RShatsky @PTarantinoMD @hoperugo @NicoleKuderer @StoverLab @CarmenCalfa @sardesai_sagar @stolaney1 @OncoAlert