1/ After ~5y of experiments/analysis, our peer-reviewed manuscript testing the 'insulin-cancer' hypothesis is online. Primarily work of talented PhD student @annizubc co-supervised by @JanelKopp and myself. Funded - @SRC_CRS @CCSResearch BC Pancreas Centre cell.com/cell-metabolis… 2/ The paper is really quite straightforward. Reducing endogenous insulin production, even slightly (first panel), leads to a significant reduction in the development of pancreatic cancer (next 2 panels - dark purple is normal pancreatic acinar tissue, light is PanIN lesions).