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Mar 28 • 15 tweets • 5 min read
A major new paper reframes aging as a systems failure of epigenetic information. Not wear and tear but a software problem. This is what the Information Theory of Aging predicts and, if correct, means aging is reversible.
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This image of the Waddington landscape shows cell identity, where the top is no identity and the valleys are specific cell identities. An fertilized egg goes from of the mountain and the cells spread out. Cells move from one valley to another during aging...