And now...with apologies to immunology collaborators & #StrepA science legends like @nikkijmoreland @victornizet@markdavies... /1
Here’s a clinician’s view:
- Human infection models are powerful tools
- Humans survive exposure to #StrepA because of dynamic, proportional, and well-timed innate & adaptive responses on our surfaces (mucosa, skin) and inside our bodies (‘systemic’) /2
Oct 16, 2021 • 6 tweets • 3 min read
So...still fighting over the false choice of Phase 3 vs challenge trials? Even in a pandemic & in countries hardly trying to limit spread, the narrow pathway to vaccines for emergency use was a tightrope & key safety signals were missed. @hic_vac@1daysooner /1
Development of new vaccines requires someone to be infected somewhere. /2 mja.com.au/journal/2020/n…
