Juha Huiskonen Profile picture
Director of Institute of Biotechnology @BIOTECH_UH, Professor of Structural Biology @helsinkiuni, Visiting Honorary Research Fellow @UniofOxford
Apr 21, 2022 8 tweets 6 min read
1/ How do proteins take their shape in the cell? Insights from our article with @JackJKelly @TheYueLab @UniofOxford @v_paavilainen @HiLIFE_Helsinki @LHapponen @lunduniversity @structbiolbxl @imperialcollege @pfizer nature.com/articles/s4159… #OpenAccess 🧵👇 2/ #AlphaFold can predict the folded protein shape, but not the complicated folding process itself. Often cells use protein complexes called chaperonins to help other proteins to fold. Here we purified a chaperonin called TRiC from cultured human cells.