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Juha Huiskonen
@JuhaHuiskonen
Director of Institute of Biotechnology @BIOTECH_UH, Professor of Structural Biology @helsinkiuni, Visiting Honorary Research Fellow @UniofOxford
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Apr 21, 2022
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8 tweets
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6 min read
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How do proteins take their shape in the cell? Insights from our article with
@JackJKelly
@TheYueLab
@UniofOxford
@v_paavilainen
@HiLIFE_Helsinki
@LHapponen
@lunduniversity
@structbiolbxl
@imperialcollege
@pfizer
nature.com/articles/s4159…
#OpenAccess
🧵👇
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#AlphaFold
can predict the folded protein shape, but not the complicated folding process itself. Often cells use protein complexes called chaperonins to help other proteins to fold. Here we purified a chaperonin called TRiC from cultured human cells.