Kashif Pirzada, MD Profile picture
Emergency Physician, fighter of misfortune and disease; Co-Chair of @CanCovSoc; Love history/politics/coding/tech/AI. #fella 🇨🇦/acc
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Sep 17 4 tweets 3 min read
Noticing a lot of your relatives are just not the same, health wise? Relatives dying after surgeries that were relatively low risk a few years ago? Today, this report from insurance giant @SwissRe puts numbers on the ongoing excess death toll attributable to Covid-19.

From the report:

"Fluctuations in excess mortality tend to be short-term, reflecting developments such as a large-scale medical breakthrough or the negative impact of a large epidemic. However, as society absorbs these events, excess mortality should revert to the baseline.

With COVID-19 this has not been the case and all-cause excess mortality is still above the pre-pandemic baseline. In 2021, excess mortality spiked to 23% above the 2019 baseline in the US, and 11% in the UK. As Swiss Re Institute's report estimates, in 2023, it remained significantly elevated in the range of 3–7% for the US, and 5–8% for the UK.

If the underlying drivers of current excess mortality continue, Swiss Re Institute's analysis estimates that excess mortality may remain as high as 3% for the US and 2.5% for the UK by 2033."

What does the percentage increase in deaths mean in real numbers? Roughly 3 million people die in the US every year of various causes (cancer, heart disease, accidents, etc). The 3-7% increase in 2023 represents a 3-7% increase in that 3m number, so roughly 90-210k more deaths. This places Covid-19 solidly among the top five killers in the US, with heart disease (700k), cancer (600k), accidents (200k) and strokes (150k), and it continues to stay there 3 years after mass vaccinations, and countless waves and variants since.

While not the killer of millions and the destroyer of health systems it was in 2020-2021, it is a leading cause of death that we must continue to respect, and take active measures to prevent in especially the elderly and vulnerable. It continues to be a leading cause of disability in the form of Long Covid.Image Here is a link to the report from Swiss Re:
swissre.com/press-release/…
Aug 10 4 tweets 5 min read
Probably the most important article you'll read all year, by @omeraziz12 in the @globeandmail
Canada is in serious trouble, and Aziz hits the nail on the head on the causes:

- Deep incompetence by politicians, who resort to PR management over making decisions. Parliament is deeply dysfunctional, with Question Period a joke, and committee hearings a farce. Trudeau but also the provincial premiers have much to answer for. Many of our leaders come from legacy wealthy backgrounds and have absolutely no idea how difficult they've made life for Canadians.

"What I realized soon thereafter was that this country was witnessing a systemic political failure, a complete inability of politicians to get change done in ways that manifested at the dinner table. An extreme form of PR and image-management had begun to take over delivering on policy in concrete ways − and the entire country was noticing. Nor was this an accident, the unfortunate consequence of polarization or inequality, but the deliberate result of multiple policy failures − as well as failures of will."

"Normally, in a democracy, social ills can be addressed by public officials. But Canada’s own political institutions have been riven by corruption and personal ambition. And now also potentially by foreign influence. Each controversy and scandal leads people away from crucial time and policy attention that could have been spent on fixing the country’s major issues. At the parliamentary level, most members of Parliament are so frightened of speaking for themselves that they are rendered powerless. This defies the very essence of the British parliamentary system, upon which Canada’s system is based, which empowers MPs to speak on behalf of their constituents and represent their true voice in the people’s chamber."

- Inattention to rising crime, especially rampant car thefts, a revolving door criminal justice system, neglect of the opioid crisis. We have the laxest justice system in the Western world. Causing someone's death will get you a 6 month sentence in one prominent example. America had mass incarceration, we have mass leniency.

"At some point, one would think that the deaths of so many innocent and vulnerable people would elicit outrage − yet life goes on as normal. Each life is precious, and when violent criminals get off easy, or without punishment at all, they learn the terrible lesson that this country does not take its own laws seriously, so why should they? When the law loses its power to deter crime, either because of prosecutors not moving forward with cases, or because of a general laissez-faire attitude toward violent crime happening in other neighbourhoods, it is the marginalized who are harmed most."

- Rising housing costs that has made nearly everyone, including me, to paraphrase A Bittersweet Symphony, a slave to massive mortgages until they die, or they are perennial renters.

"For many Canadians, the cost of living has become unaffordable. The average price of a house in the GTA is $1.1-million, and Metro Vancouver is around the same. There are certainly cheaper places to live, but the average cost of a rental in Canada has reached record highs − more than $2,100 a month. According to one major study, Canada needs to build an additional 3.5 million homes by the end of the decade and is currently only building around 200,000 a year."

- Violation of the social contract on immigration.
"In Canada, the social contract for years allowed more immigration to grow the economy, but this came with stringent criteria for who should be admitted. Today, there are more than 900,000 international students in Canada, a 170-per-cent increase over the past decade. Some of these students have been scammed by for-profit colleges. Others have been affiliated with fake schools, using their student visas as loopholes in the immigration system. The social system was unprepared for such an influx, though certain institutions benefited: colleges and universities got more fees; politicians touted rising immigration numbers; the landlord class got an endless supply of perpetual renters. Without any housing available, this has left the country unprepared to deal with multiple, overlapping economic and social crises."

Aziz asks What is the Canadian dream?
"It was a promise − less individualistic and gun-friendly than the American version, but no less ambitious. To me, the dream promised that every person here could have a decent shot at life, one that was better than that of their parents. There was emphasis on community and a strong focus on order and good government. The compact included the payment of higher taxes, and in exchange, the existence of world-class social institutions delivering for ordinary people. The immigration system worked because the same contract existed with immigrants − that they would work hard, play by the rules, become part of Canadian society through legal means, and in return, would become citizens of a highly functioning democracy where a good life was, if not guaranteed, then within reach.

The dream was based on fairness, on merit, on policies that worked. It promised breathable air and the bountiful resources of the second-largest country on Earth. It promised the principle of equality of opportunity, promised safety and peace and responsibility. It promised leaders who put the national and long-term interests of the country above their own partisan needs. The dream now feels like it’s on life support."

AmenImage Link to the article here:
theglobeandmail.com/opinion/articl…
Mar 6 8 tweets 5 min read
Wanted to share with you something near and dear to my heart.
Today my colleagues and I are proud to launch the Canadian Covid Society. @CanCovSoc

Covid-19 is thankfully not the threat it once was, but there are still significant issues with having a new disease roughly 4x as bad as Flu (and much more contagious) floating around, which also disables a lot of people as well.

In Canada it was the 3rd leading cause of death 2020, 2021 and 2022. We have the Canadian Cancer Society, and Heart and Stroke foundation for the 1st and 2nd causes, it's time we have one for the 3rd leading cause of death.

It is perfectly natural to not want to deal with this issue anymore. But that's part of the problem isn't it?
Many of us have a visceral aversion to discussing it, perhaps a natural reaction to memories of the most traumatizing days of the pandemic. But the fact remains that it's still out there, that it will continue to cause strain on our health systems, disable people, and shorten life for many of us.

We need a national body that will keep advocating for things like updated vaccines and therapies, as well as common-sense fixes that prevent the spread of disease, like cleaner indoor air (which could have been very useful stopping this nasty measles outbreak we're having).

We need a national strategy to support and improve access to care for Long Covid sufferers, many of whom are simply unable to access any care for a devastatingly disabling condition. 2 out of the 3 Long Covid advocates we approached for our launch event were not able to attend due to illness, which should tell you something! There's no way to predict who will get it, when they'll get it, and there is no cure, yet.

We are organizing a virtual press conference for 1pm (ET) today, Wednesday March 6, 2024. A video stream will begin on Youtube, and this url will forward you there: . Journalists who wish to ask questions please send me a DM and I will send you instructions to join.

Our website is up at

You'll hear more from us as we grow the range of activities offered by the Society. We would love to share resources and help like-minded groups start national societies in their own countries. Would love to see and collaborate with an American Covid Society, a British Covid Society etc.

It is time that we create a permanent effort to fight this disease, and not have these efforts subject to political whims or a societal wish to indulge in denial.covidsociety.com
covidsociety.caImage
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Nov 28, 2023 6 tweets 2 min read
Life expectancy drops for a third year in a row

C19 is the third leading cause of death, behind heart disease and cancer, ahead of accidents/trauma.

Mortality overall is up 13% across all age groups compared to 2019, and increasing every year

This should be a huge scandal! Image We are being robbed of precious life years, for no good reason except to maintain an unsustainable status quo. We are losing time with our loved ones, the economy is losing out on workers in their prime years, and there must be a better way.

Media article:
Statscan source:
and
Jun 13, 2023 5 tweets 3 min read
So much truth in this one graphic.
True story, on a recent shift, I had to run and help a patient who had collapsed on our waiting room floor, short of breath. Hypoxemic. The family was diligent, and tested before coming, and lo-and-behold, they were positive. With some help, got… twitter.com/i/web/status/1… Image I asked ChatGPT to summarize my feelings in verse, and it did an astonishing job:

In sorrow do I witness suffering's reign,
The public's decline, inflicted by this bane,
The young struck by blood clots, strokes untold,
Life's flame grows dimmer, as the years unfold.
Alas,… twitter.com/i/web/status/1…
Jun 7, 2023 6 tweets 2 min read
Today wore an N95 mask outside for the first time ever, and found it really helpful for throat irritation and that annoying choking feeling. Doesn't help for eye irritation though. Would highly recommend. If you've upgraded your home, workplace or school with enhanced ventilation and filtration to fight airborne illnesses, you're in luck: staying indoors will protect you. If not, you can jerry-rig some filters using commonly available parts:
Apr 3, 2023 4 tweets 2 min read
Had the chance to speak to Katie Dangerfield of @globalnews about Covid-19 boosters and the lack of clarity and guidelines from our advisory bodies.

I'll explain some of my reasoning why I think regular (every 6-12m) boosters are a good idea for all age groups:

1) It's always… twitter.com/i/web/status/1… The article on Global News:
globalnews.ca/news/9592598/c…
Mar 31, 2023 7 tweets 4 min read
The unprovoked death of an innocent 16 year old boy in Toronto's subway system needs to lead to radical changes to the way in which we handle criminal behaviour, and address the chronic neglect of the most vulnerable in our society.

I will go over some solutions here.

I served… twitter.com/i/web/status/1… The homeless population roughly breaks into 4 groups, which often overlap with each other. We often lump it all together, but each individual requires targeted supports depending on what factor is keeping them homeless.
Poverty is the 'easiest' to fix, just build more housing… twitter.com/i/web/status/1…
Mar 29, 2023 4 tweets 2 min read
These open letters from the AI community remind me of our frantic efforts in early 2020 to get the public and policy makers to take SARS2 seriously.
We need to slow down and study the ramifications of the new intelligent life we are potentially creating. There could be enormous… twitter.com/i/web/status/1… Training a large language model requires $100 million or so of GPUs and servers. Inference (where you ask a question and get output) maybe takes a $100k server. The big GPU clusters are known, only two companies make the right chips, and only a few chip fabs can make them, none… twitter.com/i/web/status/1…
Mar 26, 2023 7 tweets 4 min read
Some thoughts after a recent family vacation to Southern California
- Was really amazed to see the quality of indoor ventilation in almost every building we went to. Almost never saw a reading above 600, even when moderately crowded. Probably easy to do in a state where the… twitter.com/i/web/status/1… Picture of Balboa Park, San Diego This was in Little Italy in downtown San Diego, where open windows and doors is the default setting.
Mar 4, 2023 7 tweets 3 min read
Up until the early 2000s, it was normal to go to a restaurant or nightclub and get your lungs and clothes saturated with cigarette smoke.
Health effects were well known, but nothing was done. It was considered too difficult, too inconvenient.
Remind you of another health threat? It took years, but it was worker health and safety laws that finally ended it.
Now, we know cumulative Covid infections are bad for you, just like smoking. More and more studies are verifying what was suspected.
Mar 1, 2023 9 tweets 3 min read
Believe it or not, people used to fight against sanitation, and against clean water free of feces and cholera, saying it was their right to get sick... that people even died from a 'good washing'
Remind you of anyone?
H/T: @fluids_guru Crazy you say? These words were actually published in the The Times of London in 1854:
snopes.com/fact-check/lon…
Feb 28, 2023 10 tweets 4 min read
Canadians are divided on the subject of private sector involvement in our public single-payer health system. I go over some of the reasons why today with @kateygoalie on @ctvnews
ctvnews.ca/video?clipId=2… These poll results are unsurprising, our health system has been under-performing even before the pandemic; access to specialists, imaging tests, mental health resources, hospital beds was very poor to begin with. ctvnews.ca/canada/here-s-…
Feb 27, 2023 7 tweets 3 min read
How to solve access problems in our health system? Will the new funding deal between the federal and provincial governments do the trick? Will it address creeping privatization in our system? @CTVNews
ctvnews.ca/video?clipId=2… Actual new money works out to about 1-2% more funding per year for each province, not a ton of money. Ontario will get $8.4B over 10 years, and spends $75B a year currently.
canada.ca/en/health-cana… Image
Feb 22, 2023 12 tweets 4 min read
Editorial chastising the 1/3 of Americans trying to avoid infection. In the same breath, acknowledges that the elderly are being mowed down in huge numbers, but still blames the careful for holding back a return to a 'fully functional society'
time.com/6251077/covid-… The sheer chutzpah in blaming the vulnerable for trying to save their own lives.
Also, how can you give up on controlling any transmission when tools like ventilation upgrades have barely been operationalized on a large scale? Image
Feb 13, 2023 5 tweets 2 min read
Seeing some right-wing voices berating the vulnerable for being very vocal about how marginalized they've become.
Immune compromise is not that rare, it's roughly 2.7% of the US population (9 million people). Vaccines often don't work well for them. jamanetwork.com/journals/jama/… I would suggest that, if the plaintive cries of the vulnerable are becoming too bothersome for you, that you look at yourself in the mirror. Try to find some empathy; it is just a stroke of luck (and that itself is fickle) that you're not out there joining them.
Feb 12, 2023 4 tweets 2 min read
Japan (with Canada at 2nd place) has the lowest covid death rate in the G7… not with mandates, but with a public that understands deeply how to protect themselves.
I see it in my patients everyday, many use boosters, rapid tests and avoid social activities/work when sick. Avoiding crowded, poorly ventilated indoor spaces during waves is not a new concept in Japan, and has been part of public education since the beginning. They didn’t have to mandate much, the public simply did what they felt was best for themselves and their community.
Jan 31, 2023 4 tweets 2 min read
Kiddo was exposed to Covid in class last week; so far so good. Combo of good ventilation in the school, masks, and most kids in class being vaccinated seems to do the trick. 🤞 our luck holds up. Image For rapid testing, this is a good strategy suggested by the FDA, swab every 48h x 3 if negative initially.
Jan 25, 2023 8 tweets 4 min read
Recently @apsmunro posted an opinion piece explaining why he thinks kids don't get immunodeficiency post-Covid. He went so far as to declare contrary views misinformation. Problem is, one key paper he cites has a fairly glaring error.
The paper he cites did see a reduction in naive T-cells, and a return to normal levels 100 days post infection. Problem is, they didn't check for CD95 receptors which tell the difference between naive T cells, and T memory stem cells (Tscm), the next step.
frontiersin.org/articles/10.33…
Jan 24, 2023 4 tweets 2 min read
What we have in our hospitals now is a pandemic of those above 70, and those with medical comorbidities. Often it contributes to increased frailty, weakness, and worsens existing conditions. As told to @CTVNews
ctvnews.ca/video?clipId=2… If you're younger, you may think this is not a problem for you, but the collateral damage will be felt in terms of:
1) Continuously overwhelmed health systems
2) Increased Long Covid in younger groups
I explain more here:
Jan 22, 2023 7 tweets 3 min read
Had the chance to speak to @CTVNews tonight about lagging booster uptake in those above 65, Long Covid and overall system capacity.
ctvnews.ca/health/coronav… While it's good to see stress on the system decrease in recent weeks, the patients that I've admitted to hospital recently for Covid are generally older, above 70, or have medical issues (transplant patients, diabetes, heart disease, autoimmune conditions). Image