Akshay Khandelwal MD Profile picture
@HenryFordNews Assoc Div Head #Cardiology. Past Pres @MichiganACC. Past Chair @accintouch BOG. #CHIP #RadialFirst, #STEMI care sys. Tweets not advice
8 Jul 18
1/10 #STEMI from ruptured plaque, less plaque erosion. @BraunwaldEugene pic demonstrates LDL oxidized, glycated➡️cytokines release express adhesion molecules➡️monocytes roll, diapedesis➡️ingest LDL, become foam cell➡️SMC migrate, proliferate➡️some apoptosis➡️plaque
2/10 Why #STEMI on #ECG
1. Diastolic current of injury: current away from relatively depolarized injury➡️TQ depression➡️normalized on ECG➡️ST elevation
2. Systolic current of injury: current towards injury due to early repol➡️ST elevation
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