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Khodosevich Lab Profile picture
Khodosevich Lab
@KhodosevichLab
Neuroscience lab @UCPH_BRIC. We study neurodevelopmental disorders, such as schizophrenia, autism and epilepsy. Opinions do not reflect that of UCPH.
Oct 7, 2020 • 11 tweets • 7 min read
It’s comics time again! Glad to see our manuscript out in @NatureComms where we describe neuronal subtypes affected in temporal lobe #epilepsy and reveal a neuronal subtype-specific molecular phenotype.

nature.com/articles/s4146…

Here's a brief explanation of our findings 1/10 Image We used the surgically excised temporal lobe (TL) cortex from 9 individuals with epilepsy and compared against 10 non-epileptic controls. MRI of the TL showed epilepsy-associated abnormalities.
We processed >110,000 cells from these samples for #snRNAseq 2/10 Image