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Sam Klempner Profile picture
Sam Klempner
@KlempnerSam
GI medical oncologist focusing on stomach and esophageal cancer research at Massachusetts General Hospital, Harvard Medical School
Dec 7, 2022 • 21 tweets • 112 min read
@TumorBoardTues 1/15 #TumorBoardTuesday #GastricCancer #OncTwitter
Here goes

🎬Starting out with an overall poll Q

When a new advanced GC/GEJ patient presents to your clinic, your institution reflexively tests for which of the following? @TumorBoardTues 2/15 #TumorBoardTuesday

68y/o with poorly diff gastric cardia adeno, diffuse LAD, +peritoneal mets.

🧬Biomarkers HER2-, PD-L1-, MSS
🧪Pre-screened for trials & FGFR2b-, Claudin18.2+
🔦Enrolls in frontline SPOTLIGHT trial.

❓What is Claudin18.2?
❓What is SPOTLIGHT?
Oct 27, 2021 • 15 tweets • 104 min read
@MPishvaian @TumorBoardTues @SalemGIOncDoc @YJanjigianMD @DocCatenacci @rachnatshroff @gabe_a_brooks @sonbol_bassam @JoeChaoMD @JohnEbbenMDPhD 2/13 #TumorBoardTuesday

Starts on FLOT. C2 c/b😴, neutropenia, LFT ⬆️.
Unplanned CT with🙅🏼‍♂️👎response, hard to separate mass from liver capsule (not metastatic).

MDC feels risk of R1 resection, but resectable. MMR testing, complete PMS2 & MLH1 loss @MPishvaian @TumorBoardTues @SalemGIOncDoc @YJanjigianMD @DocCatenacci @rachnatshroff @gabe_a_brooks @sonbol_bassam @JoeChaoMD @JohnEbbenMDPhD @LFerri123 @MarkarSheraz @doctorC369