Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
The Knoblich Lab Profile picture
The Knoblich Lab
@Knoblich_lab
Research group @IMBA_Vienna and the @viennabiocenter.
Oct 30, 2020 • 11 tweets • 6 min read
1/11: Interested in genetic screening in #organoids? Check out #CRISPRLICHT 💡, our method for loss-of-function screening in cerebral organoids 🧠 out now in @ScienceMagazine. By @christopher_esk and @DLindenhofer. Short thread.
science.sciencemag.org/content/early/… 2/11: Screening in organoids is difficult because just like animal tissue - but unlike 2D cells - cerebral organoid tissue grows unequally, masking potential loss of function effects.
Sep 10, 2020 • 12 tweets • 5 min read
1/12 Check our latest work led by our Postdoc @fbonnay_vienna where we describe a fundamental role of mitochondrial fusion and oxidative metabolism for tumor cell immortalization, in the larval brain of #Drosophila melanogaster. sciencedirect.com/science/articl… 2/12 Our tumor model of choice is derived from asymmetrically dividing neural stem cells (NSCs) called type II Neuroblasts, deficient for the tumor suppressor gene brain tumor or brat. brat-deficient type II Neuroblasts give rise to big and lethal brain tumors.